Streptococcus dentalis: SM121_08500
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Entry
SM121_08500 CDS
T10629
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sden Streptococcus dentalis
Pathway
sden00300
Lysine biosynthesis
sden00550
Peptidoglycan biosynthesis
sden01100
Metabolic pathways
sden01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sden00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SM121_08500 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SM121_08500 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SM121_08500 (murF)
Enzymes [BR:
sden01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SM121_08500 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Cellulase
Motif
Other DBs
NCBI-ProteinID:
WPS53740
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Position
complement(1743199..1744569)
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AA seq
456 aa
AA seq
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MNLTLHEVAHLVHAKNDISQFEDVALVKPEFDSRLIGPGDLFVPLKGARDGHDFIETAFE
NGAVATFSEKVVEGHPYILVEDVLSAFQTLAAAYLQKTKVDVFAVTGSNGKTTTKDMLAQ
LLSTTYLTYKTQGNYNNEIGLPYTVLHMPEGTDKLVLEMGQDHLGDIHLLSELAHPKAAI
VTLIGEAHLEFFKDRSEIAKGKLQIADGMPEGGLLVVPADPIVDAYLPENQTVVRFGPDE
EIFITELIERKDSLTFRANFLEEAIDLPVTGKYNATNAMIAAYVALKEGVSEAAIRDSFE
TLQLTRNRTEWKKAGNGADILSDVYNANPTAMRLILETFSTIPANPNGRKLAVLADMKEL
GEQSIDLHNQMILSLSPDVLDTVIFYGQDITGLAQLASQMFPLGHVYYFKKTAEEDQFED
MVKQVKESLKEQDQILIKGSNSMNLAKLVEELENGK
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgaatctcacattacatgaagttgctcatctagtacatgcaaaaaatgatatcagccaa
tttgaagatgtggctctcgtcaagccggaatttgacagccgtttgattgggcctggagac
ctgtttgttcccttaaagggagcgcgtgatggtcatgactttattgagactgcttttgaa
aacggagccgtagccactttttcagagaaagtggtagaaggccacccttatattttggtg
gaagatgtattgagtgcttttcaaacacttgctgcagcctatcttcaaaagacaaaagta
gatgtttttgcggtgacagggtcaaatggtaaaaccaccacaaaagatatgttggcacag
cttttgtccaccacctacctgacctataaaacacaaggaaactataataacgaaattggt
cttccttatacggttttgcatatgccagaagggacggacaaactcgtccttgaaatgggg
caagaccatctaggagatatccatctcttgtcagaactggcgcatccaaaagctgctatt
gtcaccttgattggggaagcccatttggaattcttcaaagatcgaagtgagatcgcaaaa
ggaaaactccagattgcggacgggatgccagaaggtggccttctggtagttccagctgat
ccgatcgtcgatgcctaccttcctgaaaatcaaacagtcgtccgctttggtccagacgag
gagatttttattaccgagttaatcgagcgaaaggatagcttaactttccgagcgaatttc
ttagaagaagcgatcgatcttccagtaacaggaaaatacaatgcgaccaatgccatgatt
gcagcttatgttgccttaaaagaaggagtgagcgaagctgcgattcgtgatagtttcgaa
accctgcaattgacacgcaaccggacagaatggaagaaggcgggtaatggggcggatatc
ctatccgatgtctacaatgccaatccaacggcaatgcgcctaatcttagaaaccttctct
accattcctgctaatccaaatggtcgaaaattagccgtcctggcagatatgaaagaacta
ggggagcaatctattgatctgcacaaccaaatgattctcagcctctcgccagatgtcttg
gatacggttattttctacggccaagacattacgggattggcccaattagcgagtcagatg
ttcccactcggacatgtctattatttcaagaagacagctgaggaagaccagtttgaggac
atggtcaaacaagtcaaggaaagcttgaaagagcaagaccaaatccttatcaagggaagc
aattccatgaatctagccaaattagtagaggaattggagaatggtaagtaa
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