Streptococcus dysgalactiae subsp. equisimilis ATCC 12394: SDE12394_07615
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Entry
SDE12394_07615 CDS
T02017
Name
(GenBank) putative D-ala-D-ala adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sdg
Streptococcus dysgalactiae subsp. equisimilis ATCC 12394
Pathway
sdg00300
Lysine biosynthesis
sdg00550
Peptidoglycan biosynthesis
sdg01100
Metabolic pathways
sdg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sdg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SDE12394_07615
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SDE12394_07615
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SDE12394_07615
Enzymes [BR:
sdg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SDE12394_07615
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADX24969
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All DBs
Position
complement(1485606..1486973)
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AA seq
455 aa
AA seq
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MKLTLHEVAKIVDAQNNISDLDDVPLNQIEFDSRKITEGDLFLPLKGERDGHDFIDLAFE
NGAVATFSEKELPGKPHLLVNDCLKAFQTLAQYYIDKMRVDVIAVTGSNGKTSTKDMISA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPEDTEKIVLEMGQDHMGDIHLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMDSNGILIAPGDSIIDPYLPENQMVIRFGDYQ
ELNVTDIREEKDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVADEDIIEALE
SVQLTANRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKKIAVLADMKEL
GPDSVALHSQLIKQLSPDRIDQLVFYGDDIQELAQLAHEFYPEGHVQFFQKNQQEDQFED
MGRQVQQLLAPSDQILLKGSNSMGLAKLVNHLVEN
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaactaaccttacatgaagtggctaaaattgttgatgcccaaaataatatatctgat
ctggacgacgtccctctgaatcagattgagtttgatagccgtaagattacagaaggagat
ctttttttaccccttaaaggcgagagagatggacatgattttattgatttagctttcgaa
aatggagcagttgctactttctcagaaaaagaattgccaggtaaaccccatcttcttgtt
aacgattgcctaaaagcttttcaaacgttagcccagtattacatcgataagatgcgcgtg
gatgtgatagccgtgacaggttcaaatgggaaaacctctaccaaagatatgatcagcgca
gtcctatcaacaacctataaaacttataaaacgcagggaaattacaataatgagatcgga
ttaccctacaccgttctccacatgcctgaagataccgaaaaaattgttcttgagatggga
caagaccacatgggagatattcatcttctctctgaaattgcaagaccccgtattgctgtt
ttaactctggtaggcgaagcccatttagaatattttgggtcacgtgacaagattgctcaa
gggaaaatgcaaattgttgatggaatggattcaaatggcattttaattgccccaggtgat
tcgattatcgatccttatcttccagaaaaccagatggtcattcgatttggcgactaccaa
gaattgaatgttactgatattcgagaagaaaaagatagcttaacgtttacaacaaatgtg
ttagcaacacctgtgtccctacctctaccaggaaaatacaacgcgaccaatgctatggta
gcagcctatgttggcaaattgttggcagtagcagatgaggatattatcgaggcgttagag
tctgttcaactcactgctaatcgtacagaatggaaaaaagctgctaatggtgctgacatc
ttatcagatgtttacaatgccaatccgacagccatgcgcctgattttagaaacctttgct
aacatagcaaagaaccccggtggaaaaaagattgcagtgctagctgacatgaaagaatta
ggaccagattctgttgccctacattcgcagttaatcaaacaattgtcacctgatcgcatt
gaccaacttgttttttatggtgatgatattcaagagttagcccaattagcacatgagttt
tatcctgaaggacatgttcagttcttccaaaaaaatcagcaagaagatcagtttgaagac
atgggaagacaggtgcaacaattacttgctccctctgaccaaattcttttaaaagggagt
aactcaatggggctggctaaattggtcaatcatttagttgaaaattaa
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