Streptomyces drozdowiczii: NEH16_12085
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Entry
NEH16_12085 CDS
T09042
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
sdrz
Streptomyces drozdowiczii
Pathway
sdrz00230
Purine metabolism
sdrz00670
One carbon pool by folate
sdrz01100
Metabolic pathways
sdrz01110
Biosynthesis of secondary metabolites
Module
sdrz_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sdrz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NEH16_12085 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
NEH16_12085 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
sdrz04147
]
NEH16_12085 (purH)
Enzymes [BR:
sdrz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
NEH16_12085 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
NEH16_12085 (purH)
Exosome [BR:
sdrz04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
NEH16_12085 (purH)
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SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
UZK54774
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Position
complement(2716760..2718313)
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AA seq
517 aa
AA seq
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MSENKPIRRALVSVYDKTGLEDLARGLHEAGVELVSTGSTAGKIAAAGVPVTKVEELTGF
PECLDGRVKTLHPRVHAGILADLRLDAHREQLAELGVEPFDLVVVNLYPFKETVASGASD
DECVEQIDIGGPSMVRAAAKNHPSVAVVTSPERYADVLAAVKAGGFDLTARKRLAAEAFQ
HTAAYDVAVAGWFADDYAAADDSGFPDFFGTTYERQDVLRYGENPHQPAALYTSGTGGLA
GAEQLHGKAMSYNNYTDTDAARRAAYDHDEPCVAIIKHANPCGIAIADDVATAHRNAHDC
DPLSAFGGVIAVNRPVTVAMAEQVAEIFTEVIVAPAYEDGAVEVLARKKNIRVLRAPEAP
SAEVEVKQIDGGALLQVTDRLQAEGDDPANWTLATGDALSADELKELAFAWKACRAVKSN
AILLAKDGASVGVGMGQVNRVDSAKLAVERAGEERATGSYAASDAFFPFPDGLEILTAAG
VKAVVQPGGSVRDELVVEAAKKAGVTMYFTGTRHFFH
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atgtcggagaataagcccatccgccgcgccctggtcagcgtctacgacaagacgggcctc
gaagacctcgcccgcggcctgcacgaggcgggtgtcgagctggtctccaccggctccacc
gccggaaagatcgccgccgccggtgtcccggtcaccaaggtcgaggagctgaccggcttc
cccgagtgcctcgacggccgcgtcaagacgctgcacccccgcgtccacgccggcatcctc
gccgacctgcgcctcgacgcgcaccgcgagcagctggccgagctgggcgtcgagccgttc
gacctggtggtcgtcaacctgtacccgttcaaggagaccgtcgcctccggcgcgtccgac
gacgagtgcgtcgagcagatcgacatcggcggcccgtcgatggtgcgcgccgccgccaag
aaccacccgtccgtggccgtcgtcaccagcccggagcgttacgccgacgtgctcgccgcg
gtgaaggcgggcggcttcgacctgaccgcccgcaagcggctcgccgccgaggcgttccag
cacactgccgcgtacgacgtggccgtcgccggctggttcgccgacgactacgccgccgcc
gacgactcgggcttcccggacttcttcggtacgacgtacgagcgccaggacgtcctgcgc
tacggcgagaacccgcaccagcccgccgccctctacacctcgggcaccggcggcctggcc
ggcgccgagcagctgcacggcaaggcgatgtcgtacaacaactacacggacaccgacgcc
gcccggcgcgccgcgtacgaccacgacgagccgtgcgtcgcgatcatcaagcacgccaac
ccctgcggcatcgcgatcgccgacgatgtcgccacggcacaccgcaacgcgcacgactgc
gacccgctctccgcgttcggcggcgtcatcgccgtcaaccgccccgtgaccgtcgccatg
gccgagcaggtcgcggagatcttcaccgaggtcatcgtcgccccggcgtacgaggacggc
gcggtcgaggtcctggcccgcaagaagaacatccgcgtgctgcgcgcccccgaggccccg
tccgccgaggtcgaggtcaagcagatcgacggcggcgcgctgctccaggtcaccgaccgc
ctccaggccgagggcgacgacccggccaactggacgctcgccacgggcgacgcgctctcc
gccgacgagctgaaggaactcgccttcgcgtggaaggcgtgccgggcggtcaagtccaac
gccatcctgctcgccaaggacggcgcctcggtcggcgtcggcatgggccaggtcaaccgg
gtcgactccgcgaagctggccgtcgagcgcgcgggcgaggagcgggccaccggttcctac
gccgcgtccgacgccttcttccccttcccggacgggctggagatcctgaccgccgccggc
gtcaaggccgtggtccagccgggcggttcggtccgcgacgagctggtggtcgaggccgcg
aagaaggccggcgtgacgatgtacttcacgggcacccggcacttcttccactga
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