Streptomyces drozdowiczii: NEH16_16135
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Entry
NEH16_16135 CDS
T09042
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sdrz
Streptomyces drozdowiczii
Pathway
sdrz00280
Valine, leucine and isoleucine degradation
sdrz00640
Propanoate metabolism
sdrz00785
Lipoic acid metabolism
sdrz01100
Metabolic pathways
sdrz01110
Biosynthesis of secondary metabolites
sdrz01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sdrz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
NEH16_16135 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
NEH16_16135 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
NEH16_16135 (pdhA)
Enzymes [BR:
sdrz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
NEH16_16135 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
NPLP1_N
XFP_N
Motif
Other DBs
NCBI-ProteinID:
UZK55448
UniProt:
A0ABY6PTB8
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All DBs
Position
3556581..3557744
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AA seq
387 aa
AA seq
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MTVQELPGAAAYRPTPPPAWKPLTDPAPLLPDPEPYRVLGTDAVADADPELLRRLYAELV
RGRRYNAQATALTKQGRLAVYPSSTGQEACEIAAALVLEERDWLFPSYRDTLAAVARGLD
PVEALTLLRGDRHTGYDPRAHRIAPLCTPLATQLPHAVGLAHAARLKGDDVVALAMVGDG
GTSEGDFHEALNFAAVWKAPVVFLVQNNGFAISVPLAKQTAAPSLAHKAVGYGMPGRLVD
GNDAAAVHQVLSEAVARARSGGGPTLVEAVTYRMDAHTNADDATRYRGDSEVEAWRDHDP
VQLLERELTGRGLLDDEGVEEARAAAERMAAALRERMNADPVLDPMDLFTHVYAEQTAQL
REQAARLSQELAAENDQHGTEDGGAGR
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
atgacggtccaagagctgcccggcgcggccgcctaccggcccacgccgcccccggcctgg
aagccgctgaccgatcccgcgccgctgctcccggacccggagccgtaccgggtcctcggt
acggacgcggtggccgacgccgaccccgagctgctgcggcggctctacgcggagctggtg
cgcggacggcggtacaacgcccaggcgacggccctgacgaagcagggcaggctggcggtc
tacccgtcgagcaccggccaggaggcgtgcgagatcgcggccgccctggtcctggaggag
cgggactggctcttccccagttaccgcgacacgctcgcggcggtggcccggggcctcgac
ccggtcgaggcgctgacgctgctgcggggcgaccggcacaccggctacgacccgcgcgcg
caccgcatcgccccgctctgcaccccgctcgccacccagttgccgcacgccgtgggcctg
gcccacgcggcgcggctgaagggcgacgacgtggtcgcgctggcgatggtcggcgacggc
ggcaccagcgagggcgatttccacgaggcgctgaacttcgcggcggtctggaaggcgccg
gtggtcttcctcgtgcagaacaacggcttcgccatctccgtaccgctggccaagcagacg
gcagcgccgtccctggcccacaaggccgtggggtacggcatgcccggccggctggtcgac
gggaacgacgcggcggcggtgcaccaggtgctctccgaggcggtcgcccgggccaggagc
ggtggcggtccgacgctggtcgaggcggtcacgtaccgcatggacgcccatacgaacgcc
gacgacgccacccgctatcgcggcgacagcgaggtcgaggcgtggcgggaccacgacccc
gtccagctcctggagcgcgagctgaccgggcgcggcctgctggacgacgagggggtggaa
gaggcacgggcggccgccgagcggatggcggcggcgctgcgggagcggatgaacgcggac
ccggtgctcgacccgatggacctcttcacccatgtgtacgcggagcagacggcgcagttg
cgggagcaggcggcccggctgagccaggagctggccgccgagaacgaccagcacggcacg
gaagacgggggagcagggcgatga
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