Streptomyces drozdowiczii: NEH16_21390
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Entry
NEH16_21390 CDS
T09042
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sdrz
Streptomyces drozdowiczii
Pathway
sdrz00790
Folate biosynthesis
sdrz01100
Metabolic pathways
sdrz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sdrz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NEH16_21390
Enzymes [BR:
sdrz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NEH16_21390
6.3.2.17 tetrahydrofolate synthase
NEH16_21390
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
UZK56305
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Position
4711915..4713435
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AA seq
506 aa
AA seq
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MSEPRPDRPDASDPDDTFAEIVDEATQRDPDLAVIEAGSRTLRAASGPPRAEELPARPAD
PEVDKALRAVEQELAGRWGETKLEPSVTRIAALMDVLGEPQRAYPSIHITGTNGKTSTAR
MIEALLGAFDLRTGRYTSPHVQSITERISLDGAPVDPERFISTYEDVKPYVEMVDAQQPY
RLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDASVAVVTPISLDHTDRLGN
TPGEIATEKSGIIKQGATVILAQQPVDAAQVMLKKAVEVDATVAREGMEFGVVSREIAVG
GQLLTLRGLGGEYDNIFLPLYGAHQAHNAVVALCAVEAFFGVGAEQPGALDADIVRAAFA
SVISPGRLEVVRSSPTVVLDAAHNPAGARATAEGLSEAFGFSRLIGVVGASGDKDVRGLL
EAFEPIFAEVVVTQNSTERAMDADALAAVAVEVFGHDRVQVEPRLDDALEAAITLAEEED
EYAGAGVLVTGSVITVGEARLLLGRR
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
gtgagtgagccccgccccgaccggcccgacgcgtccgaccccgacgacaccttcgcggag
atcgtggacgaagcgacccagcgcgaccccgacctggcggtgatcgaggccggcagccgc
acgctgcgcgccgcctccgggccgccccgcgccgaggagctgcccgcccgccccgccgac
cccgaggtcgacaaggcgctgcgcgcggtggagcaggagctcgcgggccgctggggcgag
accaagctggagccgtccgtcacgcggatcgccgccctgatggacgtgctcggcgagccg
cagcgcgcgtacccctcgatccacatcaccggcaccaacggcaagacgagcaccgcccgc
atgatcgaggccctgctcggcgccttcgacctgcgcaccgggcgctacacctcgccgcac
gtccagtcgatcaccgagcggatcagcctggacggcgccccggtggacccggagcggttc
atctccacgtacgaggacgtcaagccgtacgtcgagatggtcgacgcccagcagccctac
cggctctccttcttcgaggtgctgaccggcatggcgtacgcggccttcgccgacgcgccc
gtcgacgtcgccgtggtcgaggtcggcatgggcggcacctgggacgcgaccaacgtgatc
gacgcctcggtcgccgtcgtcacccccatctcgctggaccacaccgaccgcctgggcaac
acgccgggcgagatcgcgaccgagaagtccgggatcatcaagcagggcgccacggtcatc
ctggcccagcagcccgtcgacgccgcccaggtcatgctgaagaaggccgtcgaggtcgac
gccaccgtggcccgcgagggcatggagttcggcgtggtctcccgggagatcgcggtcggc
ggccagctgctgaccctgcgcggcctcggcggcgagtacgacaacatcttccttccgctg
tacggcgcccaccaggcgcacaacgcggtggtggcgctctgcgccgtcgaggcgttcttc
ggcgtcggcgccgagcagcccggcgcgctggacgccgacatcgtgcgcgccgcgttcgcc
tcggttatctcgcccggccgcctcgaagtcgtccgctccagcccgaccgtcgtcctggac
gccgcgcacaacccggcgggcgcccgcgccacggccgagggcctgtccgaggcgttcggc
ttctcccggctgatcggggtggtcggcgccagcggcgacaaggacgtgcgggggctcctg
gaagccttcgagccgatcttcgccgaggtcgtcgtcacccagaactccaccgagcgcgcc
atggacgccgacgccctcgcggccgtcgccgtcgaggtcttcggccacgaccgggtgcag
gtcgaaccccggctcgacgacgcgctggaggcggcgatcaccctcgccgaggaagaggac
gagtacgcgggcgccggtgtcctggtgaccggttccgtgatcacggtcggcgaggcccgg
ctgctcctgggaaggcgctga
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