Streptomyces drozdowiczii: NEH16_23690
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Entry
NEH16_23690 CDS
T09042
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sdrz
Streptomyces drozdowiczii
Pathway
sdrz00300
Lysine biosynthesis
sdrz00550
Peptidoglycan biosynthesis
sdrz01100
Metabolic pathways
sdrz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sdrz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NEH16_23690
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NEH16_23690
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NEH16_23690
Enzymes [BR:
sdrz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NEH16_23690
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
E1-E2_ATPase
PGM1_C_vert_fung
Motif
Other DBs
NCBI-ProteinID:
UZK56683
UniProt:
A0ABY6PWZ7
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All DBs
Position
5216989..5218395
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AA seq
468 aa
AA seq
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MIALSLAEIAEIVGGQTHDIPDPAVTVSGPVVIDSRKVTPGSLFVAFAGERADGHDYAER
AVEAGAALVLATRPVGVPAIVVDDVVAALGALSRAVVGRLGATVVALTGSAGKTSTKDLI
AQLLERKGPTVYPEGNLNNEIGLPLTALRATDETKHLVLEMGARYIGDIRYLTGLVPPRI
GLVLNVGSAHIGEFGGKEQIAQAKGEMVESLPEDGIAVLNADDPLVRAMSSRTKARVVLF
GEGADADVRGEDVHLTDDGRPAFRLRTPTGCSEVTMRLYGEHHVSNALAAAAVAHELGLS
ADEIAEGLSEAGSLSRWRMEVTERPDGVTFVNDAYNANPESMKAALRALVAMGKGRRTWA
VLGLMAELGDASLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEESVHVS
DAQAAVDLLRRELRPGDVVLVKASRSVGLEQVVTALLENATEGEVAGR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctttccctcgccgagatcgccgaaatcgtcggcgggcagacgcacgacata
ccggatccggcagtaaccgtcagcggaccggtcgtcatcgactcccgcaaggtgaccccc
ggcagcctcttcgtcgccttcgccggcgaacgggccgacggccacgactacgccgagcgc
gccgtcgaggcgggcgcggccctcgtcctggccacccggcccgtcggcgtgcccgcgatc
gtcgtggacgacgtcgtggccgccctcggggcgctctcccgcgccgtcgtcggccgcctc
ggcgccaccgtcgtggccctcaccggctccgcgggcaagacctccaccaaggacctcatc
gcgcaactcctggagcgcaaggggcccaccgtctacccggagggcaacctcaacaacgag
atcggcctgccgctcaccgcgctgcgcgccaccgacgagaccaagcacctggtcctcgaa
atgggcgcccgctacatcggggacatccgctacctcaccggactcgtcccgccgcgcatc
ggcctcgtgctcaacgtcggcagcgcgcacatcggcgagttcggcggcaaggagcagatc
gcccaggccaagggcgagatggtcgagtcgctccccgaggacggcatcgccgtgctcaac
gccgacgaccctctcgtacgcgccatgtcctcccgtaccaaggcccgcgtcgtcctcttc
ggagagggcgcggatgcggacgtacggggtgaagacgtgcacctcaccgacgacggacgc
cccgcgttccgcctccgaacacccaccgggtgcagcgaggtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcctgtcc
gcagacgagatcgccgaagggctctccgaggcgggctccctctcccgctggcgtatggag
gtcaccgagcgtccggacggcgtgacgttcgtcaatgacgcctacaacgccaaccccgaa
tccatgaaggcagcgctccgcgcgctggtcgccatggggaaggggcgtcgtacgtgggcg
gtgctcggcctcatggccgagctgggcgacgcctcgctcgccgagcacgacgcggtcgga
cggctcgccgtccgactcaacgtcagcaagctcgtcgcggtcgggggcagagaagcctcc
tggctgcaactgggcgcatacaacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggctgccgtcgacctgttgcgcagggaactgcgcccgggagacgtggtgctg
gtgaaggcgtcccggtcggtcggcctcgagcaggtcgtcacagcactgctggagaacgcg
accgagggcgaggtcgcgggccgatga
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