Streptococcus dysgalactiae subsp. equisimilis GGS_124: SDEG_1462
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Entry
SDEG_1462 CDS
T00932
Symbol
murF
Name
(GenBank) putative D-Ala-D-Ala adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sds
Streptococcus dysgalactiae subsp. equisimilis GGS_124
Pathway
sds00300
Lysine biosynthesis
sds00550
Peptidoglycan biosynthesis
sds01100
Metabolic pathways
sds01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sds00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SDEG_1462 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SDEG_1462 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SDEG_1462 (murF)
Enzymes [BR:
sds01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SDEG_1462 (murF)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAH81957
LinkDB
All DBs
Position
1:complement(1416606..1417973)
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AA seq
455 aa
AA seq
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MKLTLHEVAKIVDAQNNVSDLDDVPLNQIEFDSRKITEGDLFLPLKGERDGHDFIDLAFE
NGAVATFSEKELPGKPHLLVNDCLKAFQTLAQYYIDKMRVDVIAVTGSNGKTSTKDMISA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPEDTEKIVLEMGQDHMGDIHLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMDSNGILIAPGDSIIDPYLPENQMVIRFGDYQ
ELNVTDIREEKDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVADEDIIEALE
SVQLTANRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKKIAVLADMKEL
GPDSVALHSQLIKQLSPDRIDQLVFYGDDIQELAQLAHEFYPEGHVQFFQKNQQEDQFED
MGRQVQQLLAPSDQILLKGSNSMGLAKLVNHLVEN
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaactaaccttacatgaagtggctaaaattgttgatgcccaaaataatgtatctgat
ctggacgacgtccctctgaatcagattgagtttgatagccgtaagattacagaaggagat
ctttttttaccccttaaaggcgagagagatggacatgattttattgatttagctttcgaa
aatggagcagttgctactttctcagaaaaagaattgccaggtaaaccccatcttcttgtt
aacgattgcctaaaagcttttcaaacgttagcccagtattacatcgataagatgcgcgtg
gatgtgatagctgtgacaggttcaaatgggaaaacctctaccaaagatatgatcagcgca
gtcctatcaacaacctataaaacttataaaacgcagggaaattacaataatgagatcgga
ttaccctacaccgttctccacatgcctgaagataccgaaaaaattgttcttgagatggga
caagaccacatgggagatattcatcttctctctgaaattgcaagaccccgtattgctgtt
ttaactctggtaggcgaagcccatttagaatattttgggtcacgtgacaagattgctcaa
gggaaaatgcaaattgttgatggaatggattcaaatggcattttaattgccccaggtgat
tcgattatcgatccttatcttccagaaaaccagatggtcattcgatttggcgactaccaa
gaattgaatgttactgatattcgagaagaaaaagatagcttaacgtttacaacaaatgtg
ttagcaacacctgtgtccctacctctaccaggaaaatacaacgcgaccaatgctatggta
gcagcctatgttggcaaattgttggcagtagcagatgaggatattatcgaggcgttagag
tctgttcaactcactgctaatcgtacagaatggaaaaaagctgctaatggtgctgacatc
ttatcagatgtttacaatgccaatccgacagccatgcgcctgattttagaaacctttgct
aacatagcaaagaaccccggtggaaaaaagattgcagtgctagctgacatgaaagaatta
ggaccagattctgttgccctacattcgcagttaatcaaacaattgtcacctgatcgcatt
gaccaacttgttttttatggtgatgatattcaagagttagcccaattagcacatgagttt
tatcctgaaggacatgttcagttcttccaaaaaaatcagcaagaagatcagtttgaagac
atgggaagacaggtgcaacaattacttgctccctctgaccaaattcttttaaaagggagt
aactcaatggggctggctaaattggtcaatcatttagttgaaaattaa
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