Seriola dumerili (greater amberjack): 111219247 Help Entry 111219247         CDS       T05606                                  Symbol ubr4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism sdu  Seriola dumerili (greater amberjack) Brite KEGG Orthology (KO) [BR:sdu00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:sdu04121]     111219247 (ubr4) Enzymes [BR:sdu01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      111219247 (ubr4) Ubiquitin system [BR:sdu04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     111219247 (ubr4) SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4_TPR UBR4_Ub UBR4 zf-UBR_1 zf-UBR DUF7637 Motif Other DBs NCBI-GeneID:  111219247 NCBI-ProteinID:  XP_022597588 LinkDB All DBs Position Unknown AA seq 5156 aa AA seqDB search MASSGGDGEHEWTAAVRPLLSASYTAFETKELPQLIGSIINSESDILHHDKQYEPFYSSF VALSAHYITTVCGQIPRNQLLSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLC TGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELPSAVNPELRQKEVQMNFFNQL TSVFNPDLTTILASPSAAQMQAESDCDDQTTDQAVQAKMKNAFVSQNVSSLQELGGSEKL LRVCLNLPYFLRYINRFQDAVSANSFFIMPATVADATAVRNGFHSLVIDVTMALDTLSLP VLEPLTPGRLLDMTVLALSCLYAGVSVATCMAILQVGSGLQLRSASTGTKEEDYENDAAT IVQKCLEIYEMIGQAISNSRRAGGEHYQNFQLLGAWCLLNSLYLILNLSPTALADKGKEK DPLAALRVRDIAARTKDGAGSPKLGPGKGHQGFGVLSVILANHAIKLLTSLFQDLQVEAL HRGWASDGPPAELNIMAQSTSIQRVQRLIDSVPLTNLLFTLLSTSYKKACVLQRQRKGSV SSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGLWFEETISPTKDKVAPPPPPPPPP LETSPRLKSPSKQNPSENGNILAGRKDPELFLSLASSILNFITTSMLKSRNNFIRNYLSV SLTEQHMATLASIIKDVDKDVKGSSDEVFSLALYHFNHTLVTSDLPSPALQSTLLQQLGV APFSEGPWPLYIHPQSLSVLSRLLLIWQHKASVQGEPDVPECMKVWERFLGTLKQHTIQG SVHGEDDLNVEHLQLLLLLFHNLSERGRRSVLTLVTQAITEVAQSRDSQLKAVPLNLARL LLVFDYLLRHYSKAPLYLFEQVQYNLLTPPSSGPSSVQEGGKRSSLPLYYGFKEVEENWA KHCSADSNVQPKFYCVLSPEASEDDISRLDSKVFPKLFNGAVKYDELYAWLISLLAAGSQ FDTARRQENKPITPMEACSLQYYFLVLWRILGVLPPSKAYMEQLKTGCSDPSESDILHTL RWSSRLRVSTYVNWIKEHLVKQGMKTDQAASLVEMTSAKCSTVKYDVELAEEYIARQIST FSCVDPNVILPLNQLPSLQAIYTLDAVISKVQVSLDDHLSKVAIEADTHKSSEITKNLLP ATLQLTDVYTAFTRSYLLMNIPEEGENKLTDAKLQGYAAVLSIGSTRCKANMLGHSIMQN LPSAVQTICETWNSIHTNEFPNIGSWRNAFANDTIPSESYISAIQAAHLGTLSCQSLPLV SSLKHILLSLVRLTGDLIVTEELNPSQVVRTLLPLLLESSTESVAEISSTSLERILGPSE SDAFLARIYERLVTGCYNIIANHSDPNSGLDESVLEECLQYLEKQLESSQVRKAMEEFFS FSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLCLCGSLAQLACVEPS RLQSWLTRMTATPPKDSEQLEIVQENRQLLQLLTTHIVRDNSQVGEGVCTVLLSTLIPMA TDMLSNGDGTGFPELMVIMATLASAGQGAGHLQLHRAAIDWLTRCKKYLTQKNVVEKVST NVSQGKHASMLECSCHIISYLADVMNALRQSSGQGTSAMLMEGEEKAMEVDSDWVEELAV EEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTVCAKVCHKDH EISYAKYGSFFCDCGAKEDGSCQALVKRSPSSGMGSTLKESSAFQSELRMPESAIRHQNA SPSDKGKVTICDGKSGDEDRPKKSSVCKSIEGCQEELLAQVMGSSTAAVILEMLMFLMEA IQTNFQQASAVGSSSRAQQALNELHNQDKNVEMTDQLMVPTLGSQEGAFENVRMNYSGDQ GQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSTLLKQADSSKRKLT LTRLASAPVPFTVLSLTGNPCNEDYLAVCGLKDCHVLTFSSTGSVSDHLVLHPQLATGNF IIKAIWLPGSQTELAIITADFVKIYDLSVDALSPMYYFLLPSSKIRDATFLFNEEGKNII VIMSSAGYMYTQIMDESSSAQHGPFYVTNVLEINHEDLKDSNGQVAGGGVSVYYSHVLQM LFFSYSQGKSFAATVSRSTTDVQRLFPINIKGSNGGSSKMSPALCQWSEVMNHPGLVCCV QQTTGIPLVIMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTASNEQQRTTMILLCEDGSLR IYMANVDNTSYWLQPSLQPSCGISIMKPVRKRKAAATTTRTSSQVTFPVDFFEHNQQLTE VEFGGNDLLQVYNGQQIKHRLNSTGMYVANTKPGGFTVEAVNNNSSMVMTGMRVQVGTQA IERAPSYVEVFGRTMQINLTRARWFDFPFTREEALQADKKLSIFIGASVDPAGVTMLDSI KIYGKTKEQFGWPEDPPEDFSSASVNNVCSPNLNQGNGASDGDIATPTTTSGTVLERLVV SSLEALESCFAVGSSNEKEKNKAAALELATLLLSMPTPAGVQQQTKGLLASLHTSRTAYH NHKDQSLLSNAVQCLNSCTREGRELDPDVFQRLVITARSIAIMRPNNLVHFTETKSLHQD PEMTEDGQKHLDGESCNFITQLMNNFWKLHALKPKNAFLAPACLPGLTHVEATVNALVDI IHAYCTCELDYINVASKIYMQMLLCPDTAVSFACKQALIRVLRPRNKRRHVTLPSPPRSN TPMGDKDDDDDDDADDKMQSSVLTGGEEGRQESQEQSEVDHGDFEMVSESMVLETAENVN NGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGL SGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPAEHGGSVGSESGGSAID SVAGEHSVSGRSSAYGDTAVEGHPAGPGSVSSSTGAISTTTAQQEGEGSEGEGETEGDIH TSNRLHMVRLMLLERLLQHLSQLHNVGGVQAIPYMQVILMLTSDLDGEDEKDKGALDDLL AQLIAELGMHKKDVSKKNERSSINEVHLVIMRLLSVFMSRTKSGSKASSESSSLISNATA TALLSLGAIDYCLHVLKSLLEFWKSQQGEEEPVTTSQLLRPHTASSPPDMSPFFLRQYVK GHAADVFEAYSQLLTEMVLRLPYQIKKIADTNPRIPPPVFDHSWFYYLSEYLMIQQTPFV RRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRSIKKLLEEQGIFLRAGVVTATSGSALQY DTLISLMEHLKACAEIATQRTINWQKFCMKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCA LCGSKVLASSSSSSFSGGGSSSSGQTGASQSSQSKSSSKKSKKEDKEKDKEGDGVGSQED QLCMGLVSQLNKFADKETLIQFLRCFLLESNSSAVRWQAHCLALHIYRNSNKSQQELLLE LTWAIWPELPAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRAQNHILTNHPN SNIYNTLSGLVEFDGFYLESDPCLVCNNPEVPFSNIKLSSIKVDTRYTTTQQVVKLIGSH TISKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKI DLPLPIVASNLMIEFSDFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRS INYDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVTNINTLLDKADRV YHQLMGHRPQLESLLSKVNEAAPEKPQDDTGAGSGLGTSSANVNRYIQQLAQEYSGDCKT SFDELSKIIQKVLASRKELLEYDLQQREAATKSSRSSSSHQPTFTASQYRALSVLGCGHT SSTKCYGCASAVTGHCITLLRALATNPALRQILVLQGLIRELFEYNLRRGTAAMREEVRQ LVCLLTRDHPEATQQMNDLIIAKVSAALKGHWANPDLVSNLQYEMLLLTDSISKEGGCWE LRLRCALSLFLMSVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDAATESLTTVRP YSNEIHAQAQLWLKKDPKASYEAWKKCLPARYQETVSKPQGKAELRKQYLLEKYAWKWKQ FMRSRKGEGLFPRLLKLSHNNWLRQVLFTPATQAARQAACTIVEALTTIPSRKQQVLDLL TSYLDELSVAGECAVEYLGLYQKLIKPTHWKVYLAARGVLPYIGNLITKEIANLLALEEA TLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDE TQDMLLEMLEDMTTGTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEV TEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGM ELLVNNKIISLDLSVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIESLDSTTDEE EDDEEVYKMAGVMAQCGGLECMLNRLSGIKDFKQGRHLLTVLLKLFSYCVKVKINRQQLV KPEMNTLNVMLGTLNLALVAEQESKDSGGASIAEQVLSIMEIILDEANAEISEDKGNLLL TGDKDQLIMLLDQINTPFVRSNPSVLQGLLRIIPYLSFGELEKMRILVERFKPCCSFDKY DEEHSADDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQSALDYMKKHIPNAKNLDA DVWKKFLSRPALPFILRLLRGLATQHPPTQVLIGTDSITNLHKLEQVSSDEGIGTLAENL LEALREHSDVNLKIEAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTSLLKQM EELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEDFENKPRKQQGYSTVSHFNIVH YDCHLAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECT GQREPTYQLNIHDTKLLFLRFATEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRAT SREEKNLQSFQEQPCEKWMESSYEVEGPHYFTILAMHIMPPERWRSSRIYFLRRLLVTAH ARKVSGVCTNKLTDKAPKEYAVYRSPLLFWGLVDLVYDMFRKVPTSNTEGGWSFSLAEYV RHNDMPIYEASERVLRAFQDELMPAESLSEFFDVVGLLSEIADPDLFLQDLLNSLP NT seq 15471 nt NT seq  +upstreamnt  +downstreamnt atggcgtcgagcggaggagatggggaacacgaatggacagcggcagtgcggccgctttta tcggcttcatacaccgcttttgaaacgaaagagctacctcagcttattgggtctataatc aacagtgaatcagacattcttcaccatgacaaacagtatgagcctttctactcatcattt gtggcactctctgcacattacatcaccacagtatgtggacaaataccaagaaatcagttg ctgtcagttgctgcagcgtgcaaagtgttgattgagttctcattgctgcgcttggagaac ccagatgaggcatgtgcagtatcacagaaacacctgattcttctaataaaaggactttgc actggctgcagcagactagatcgcacagaaatcattactttcactgctatgatgaagtct gccaagttgcctcaaaccgtcaagaccctttcagatgtggaagatcagaaggagttgccc agtgctgtgaacccagagcttcgacaaaaagaagtacaaatgaacttctttaatcaactg acttcagtttttaaccctgaccttaccaccatcttggcctccccatcagcagcacaaatg caggctgagagtgattgcgatgaccaaaccacagatcaagctgttcaggccaaaatgaaa aatgcctttgtctctcagaatgtgtcaagcttacaggaacttggtgggtctgagaagttg cttcgagtgtgcctcaacctgccctactttctacgctacatcaaccgtttccaagatgct gtatcagccaactctttctttatcatgcctgccacagtggctgatgccactgctgttcgc aatggatttcattcactggtgatagatgtaaccatggctttggacacactttccctgcct gtactggagcccttgacaccagggagattactggatatgaccgtgctggctttgagctgt ctctatgctggtgtgagtgtggccacttgcatggccattctgcaggtaggaagcggcttg cagcttcgatctgcctccactgggactaaagaggaggactatgaaaatgacgcagcaaca attgtccagaaatgtctggagatctatgaaatgattggacaagccatcagcaactcccgc agagctggaggagagcattatcagaacttccagctgcttggagcctggtgccttttgaac agcctgtacctgattcttaacctgagtccgactgccctggcggataaagggaaagaaaag gatcctctggctgccctgcgtgtccgggatattgctgctcgcaccaaggatggcgcagga tcgcctaagcttggtcctggcaaaggacaccaaggatttggagttctgtctgttatcctg gcaaatcatgccatcaaacttttgacttcacttttccaggatctgcaagttgaggctctc caccggggttgggcgagtgatgggccaccagctgagctcaacatcatggcacagagcact tccatccagagggtccaaaggctcatcgactctgtgcccctgaccaatctactcttcacc cttctctccacttcctacaaaaaggcttgtgttctccaacggcagaggaagggttcagtc agcagtgatgccagtgcttctacagattcaaacacctactacgaggatgatttcagcagt acagaggaggatagcagtcaagatgatgacagtgaacccatcttggggctttggtttgaa gagacaatttcacccaccaaagacaaagtagctcccccaccaccacctccaccccctccc ctggagacatctcccagactgaagagccccagcaagcagaatccgagtgagaatggcaac attttagctggccgtaaagacccagagctgtttctcagtttagcctccagcattctgaac ttcatcaccacctcaatgctcaagtccaggaacaacttcatccgcaactacctgagcgtg tctctcacagagcagcacatggctacacttgccagtatcatcaaagatgtggacaaagat gtcaaaggctcctcagatgaagtgttttctttagctctgtatcatttcaaccacaccttg gtgacatcagatcttccatcccccgccttgcagagcacccttcttcagcagttaggtgtt gcgcccttttcagagggtccctggcctctgtacattcatccacagtcgttatcagtcctc tccagacttctcctcatatggcagcacaaagccagtgtgcaaggagaaccagatgtgcct gaatgtatgaaagtctgggaaaggtttttgggaacgttgaagcaacacactatccagggt tctgttcatggagaggacgaccttaatgtggagcacctccagctgctgctgctccttttc cacaatctgtcagagcgtgggcgacggtcagtcctcaccctggtcacccaggccatcact gaagtggcacagagcagagactcccagctgaaggctgtgcccctcaacctggcccgcctg ttgctggtgtttgactacctcctgcgccactactccaaggctcccctgtacctttttgaa caggtgcagtataacctcctcaccccaccctcctctgggccaagttctgtccaggaaggt ggcaaacgcagcagtctccctctttactatggattcaaagaggtggaggagaactgggct aaacattgttcagcagattcaaatgttcaacccaaattctactgcgttctgtcccctgag gcgtctgaagatgatatcagcagactagacagcaaggtttttccaaagttgttcaatgga gcagtgaaatacgatgaattgtatgcgtggctcatctcactcctggcagcaggttctcag tttgacacagcaagaagacaggagaacaagccgatcactcctatggaggcctgctccctt cagtactacttcctagtactgtggaggatcctgggtgttttacctccctcgaaagcctac atggagcagctgaagactggctgcagcgatcccagcgagagtgacatcctgcacacactg cggtggtcctcacgtctccgggtatctacctacgtaaattggatcaaggaacacttggtg aagcagggaatgaaaacagaccaagcagcctcactagttgagatgacatctgctaagtgc agtactgttaaatacgatgtggagctagcagaggagtatattgcaagacagatttccacc ttctcctgtgtagacccaaatgttattcttccacttaatcagttaccctctctacaagcc atctatacactggatgcagtcatctctaaagtgcaggtttccttagatgaccatctatcc aaggttgccattgaggcagacacccacaaatcttctgagatcacaaagaacctgctgcca gccacactacagctcactgatgtttacacggccttcacaaggtcttacctactaatgaac atcccagaggaaggagagaacaagctgacagatgccaagctccagggttacgccgcagtt ctgtctattggctccactcgctgcaaggccaacatgctcggtcatagtatcatgcagaac ttaccatcggctgtccagacaatatgtgagacttggaacagcatccacaccaatgaattt cctaacattggctcatggcgaaatgccttcgccaatgataccattccatcagagagctac atcagtgccatccaagcagctcacctgggcacactgagttgtcagtccttgcctctggtc tcttctcttaaacacatcttactctcgctggttcgcctcactggcgacctcattgtcaca gaggagcttaatccttctcaggttgtgcgcaccctgctgccgctcctcctggagagcagc acagagagtgtggctgagattagcagcacctcactggagcgcatccttggcccatcagag tcagacgcctttctagctcgcatctacgagcgtttggtgactggatgttacaacatcatt gccaatcattcagaccccaacagtggtttggatgagtctgtccttgaggaatgccttcag taccttgaaaaacagcttgaaagcagtcaagtccgcaaggccatggaagagttcttttca ttcagtggtgagctcgtccagattatgatggcaacagccaatgaaaacctgtcagccaag ttctgcaacagggtgctgaagttcttcaccaagcttttccagctcacggagaagagccca aaccccagcctgttgtgcctgtgtggctctctggcccaactggcctgtgtggagccctct cgactgcagtcctggctgacacgcatgacagccacaccaccaaaggattcagaacagctg gaaatagtgcaggaaaaccgacagcttctgcagctgctgaccactcatattgtgcgtgac aacagccaggtgggtgaaggagtttgcactgtcctcctcagcacactcattcccatggca acagacatgctgtccaatggggacggaacaggctttcctgagctcatggtcatcatggcc acacttgccagcgccggacagggggccggccacctgcagctgcacagagcagctatcgac tggctgaccagatgcaaaaagtatttaacacagaagaatgtcgtggaaaaagtgagcaca aacgtatcccaaggaaagcatgcaagcatgctagaatgctcctgccacatcatctcctat ctggctgatgtaatgaatgccttgcggcaaagcagtggacaaggcacctcagcaatgctg atggagggagaagagaaggccatggaagtggactcagactgggtggaggaacttgcagta gaggaggaagattcccaggcagaggactctgatgaagactccctttgcaacaaactctgc accttcaccattactcagaaggagttcatgaaccagcactggtaccactgtcatacctgt aagatggtcgatggggtaggtgtgtgcacagtgtgcgccaaggtctgtcacaaagaccat gagatctcctatgccaaatatggctctttcttctgtgactgcggtgccaaagaggatggc agctgccaggccttggtcaaacgcagccccagcagtggcatgggctccactctcaaagag tcttctgcgttccagagtgaactgcgtatgcctgagagtgctatccgccaccagaatgcc tcaccctctgacaagggcaaggtcacaatctgtgatggcaaatctggagacgaggacaga cctaagaagagcagtgtgtgcaagagcattgagggctgccaagaagagttgctagcacaa gtgatgggatcatccactgcagcagtaatactggagatgctcatgtttctcatggaagcc atccagaccaacttccagcaggcatcagcagtgggaagcagcagccgggctcagcaagcc ctcaatgaactgcacaatcaggacaaaaatgtagagatgacagaccagttaatggtgccc acacttggctctcaggaaggagcttttgagaatgttaggatgaactatagtggtgaccag ggacaaactatacgccagctcatcagtgcacatgtcctgcgccgtgttgccatgtgtgtc ttgtcctcaccccatggccgccgccagcaccttgcagtcagccatgaaaagggaaagata acagttctccagctatccactctcctgaagcaagctgactcgagcaagaggaagctaaca ctgactcgcctggcttcagccccagtccctttcactgtcctcagtctcacaggaaaccct tgtaatgaagactacctggctgtgtgcggcctcaaggactgccatgtactaactttcagc agcacagggtctgtgtcagaccatctggtgttgcacccacaactggctacaggcaacttt atcatcaaagctatctggttacctggctcgcagactgaacttgccatcatcactgctgac tttgtcaagatatatgacttatcagtggatgccctgagtccaatgtactacttcctgctg ccaagttccaagatccgtgatgctacattccttttcaatgaagaggggaagaacattatt gtcatcatgtcttcagcaggttacatgtacacccagatcatggacgaatctagcagtgcc caacacggccctttctatgtgacaaatgttttggagataaaccacgaagacttgaaggat agcaatgggcaggtagccggcggtggtgtgtcggtctattactcccatgtgcttcagatg cttttcttcagctacagccagggaaagtcctttgctgccacagtgagccgtagcaccacc gacgtgcagaggctcttccccatcaacatcaaaggctctaatggcggtagcagtaagatg tcacctgctctgtgccagtggtctgaggtcatgaaccacccaggcctggtgtgctgtgtg cagcagacgacaggcataccactggtcatcatggtcaaacctgacaccttcctcatccaa gagattaaaactctgccagccaaagctaagattcaagatatggtagccatccgacacact gccagtaatgagcaacagcgcactaccatgattcttctctgtgaagatgggagcctgcgg atctacatggccaatgtggataacacctcctactggctccagccctcactgcagcccagc tgtggtatcagtatcatgaagccggtccgcaagcgcaaagcggctgctaccaccacccga acctccagtcaggtgacatttccagtggacttctttgaacacaaccagcagctgacagag gtggagtttgggggcaatgacttgctgcaggtctacaatggacagcagatcaaacacagg ctcaattccactgggatgtatgtggccaacacaaagcctgggggatttacggtggaagca gtcaacaacaacagttcgatggttatgacaggcatgcgggtgcaggtgggcactcaggcc attgagagggctccttcctacgtggaggtgtttggccgaaccatgcagataaacctgaca agagcccgttggtttgacttccccttcaccagagaggaggccctgcaggctgacaagaag ctgtctatctttattggagcatctgttgacccggctggagtcaccatgcttgattcaatc aagatctacggtaaaaccaaggagcagtttggctggcctgaggatccaccagaagacttc tcctctgcctcggtcaacaatgtctgcagtcccaacctcaaccagggcaatggtgcctct gatggagacatagccacccccactaccactagtggcactgtgctggagaggttggtggtc agttcccttgaggctttggaaagctgctttgcagtaggttcctccaatgaaaaggagaag aataaggctgcagcgctggagttggccactctactcctctccatgccgacccctgcaggt gtgcagcagcagaccaagggacttcttgctagcctgcacaccagtcgtaccgcctaccac aatcacaaggaccagtccttgttgagtaacgcagtgcagtgcctaaatagctgcactcgt gaggggagggagcttgaccctgatgtcttccagaggcttgtgatcactgcccgctccatt gcaatcatgagacccaacaacttggtgcatttcacagaaacaaagtcactacaccaagat cctgaaatgacagaagatgggcaaaaacatctagatggcgaaagctgtaacttcatcaca cagctgatgaataacttctggaagcttcatgccctcaaaccaaagaacgcatttcttgca cctgcttgcctgccgggcctaactcatgtggaagcaacagtaaatgccttggtggacatc atccatgcatactgcacatgtgaactggattacatcaatgtagcctccaaaatctacatg cagatgttactatgccctgacacagctgtgagttttgcttgtaagcaggctctaatcaga gtgcttagaccaagaaacaaacggcgacatgtgacccttccgtctcccccacgctctaac acaccaatgggagacaaggatgatgatgatgatgatgatgcagatgataaaatgcagtca tcagtgctgactggaggagaagagggtagacaggagagtcaggagcagagtgaagtggac catggtgactttgagatggtgtctgaatccatggtcctggagacggcagagaatgtcaac aatggaaatccatctcccctcgaggctctgctggctggagccgaaggcttcccgcccatg ctggacatccctcctgatgcagatgatgaaactatggtagagctggccatcgctctcagc cttcagcaggatcaacaaggcagtagcagcagtgcccttggccttcagagccttggcctg tctggccaagccccaagctcctcttcactggatgctggtaccctttcggacaccactgca tcagccccagcgtcagatgatgagggcagtacagctgctacagatggctccacgctgcgg acctccccagctgagcatggaggcagtgttggctcagagagtggaggttctgcaatcgac tctgtagcaggggagcacagtgtgtcgggacgcagcagtgcatatggggacacagcagtg gagggccaccctgcaggtccaggcagtgtgagttcaagcactggagccatcagtaccacc acagcacagcaggaaggtgaaggctcagagggagaaggagagactgagggagacatccat acaagcaacaggctgcacatggttcgtcttatgctcctggagcgtttgcttcagcacctt tctcagctccacaatgtgggtggagtccaagccatcccttacatgcaggttatactcatg ttgacctctgacctggatggcgaggatgaaaaagataagggcgccttggatgacctgctt gcacagctcattgccgagcttggcatgcacaaaaaggacgtgtccaagaagaacgagcgt agctccatcaatgaagttcacctggttatcatgagactgctcagcgtctttatgtctcga accaagtctggctctaaagcttcttctgagtcatcatccctgatttccaatgccacagca actgccttgcttagcctgggtgccattgactactgtctccatgtgctcaagtcgctcctg gagttttggaagagccaacagggtgaagaggagcctgtgaccaccagccagctcctccgc ccacacacagcctcctctcctccagacatgagccctttcttcctacgccaatatgtcaag gggcatgctgctgatgtgtttgaagcctactctcagctcttgactgaaatggtcctgcgg ctgccatatcagatcaagaagattgctgacaccaaccctcgtatcccacctcctgtcttt gaccattcttggttctactatctgtctgaatatctgatgatacaacagactccgtttgtc aggaggcaagtgagaaagctattgttgttcatctgcggctccaaagaaaaatatcgtcag ctgcgggatctgcacactcttgactctcatgtgcgcagcatcaagaagcttctggaggag cagggcatcttcctccgggccggtgtggtcacagccacgtcaggttcagctctacagtat gacacactcatcagtctgatggaacatctgaaggcttgtgctgaaattgccactcagagg acaatcaactggcagaagttctgcatgaaagatgactctgtgttgtacttcctgctccag gtcagctttcttgtagatgagggcgtttccccagtactgctgcaactgctctcctgtgcc ctgtgtggcagtaaggtgctggccagctcctcctcttcatcattctcaggaggaggctcc agtagttctggacagacaggagcttctcagtcttctcagagcaagtcctccagtaaaaag agcaaaaaagaggacaaggagaaagacaaagaaggtgatggagttggcagccaggaggat cagctgtgtatgggtctggtcagtcagctgaacaagtttgcagacaaagagacactcatc cagttcttacgctgcttcctgctggagtcaaactcatctgctgtgcgctggcaagcccac tgcctggcacttcatatctacaggaactccaataagtctcagcaggagctactgctggaa ctaacttgggccatctggcctgagctccctgcatatggccgcaaagctgcccagtttgtc gacctgcttggatacttctccctcaagactcctcagacagagaaaaagctgaaggagtat tctcagaaagctgtggaaattctgagagcacagaaccatatcctgacgaatcaccccaac tccaacatctacaacactctgtcaggtttagtggagtttgatgggttttacctggaaagt gacccctgcttggtatgcaacaatccagaagttcccttctcgaatataaaactgtcatct atcaaagtcgacacacgctacaccaccacacagcaggttgtcaagctaattggcagccac accatcagcaaagtcacagtgaagatcggtgacctcaaacgcacaaaaatggtccgcacc atcaatctctactacaacaaccggactgtacaggctatcgtggagctgaaaaacaagcct gcacgttggcacaaagccaagaaagttcagctgacccctggacaaacggaggtgaagatc gaccttcccttacccattgttgcatccaacctgatgattgagttctctgatttctatgag aactaccaggcatccactgagaccctgcaatgtcctcgctgcagtgcctctgtgccggcc aaccctggggtgtgtggcaactgcggtgagaatgtgtatcagtgccacaagtgcaggtct atcaactacgatgaaaaagaccccttcctgtgcaatgcctgtggtttctgcaaatatgcc cgatttgacttcatgctttatgctaaaccatgttgtgctgtggatcccattgagaatgag gaagacaggaaaaaggctgtgaccaacatcaacaccctgctggacaaagctgacagggtc taccaccagctgatgggacaccgaccccagttagaaagcctcctgtctaaagtcaatgag gcagcaccagaaaaaccacaggatgacactggggcaggttcaggacttggaacatcctct gctaatgtgaaccggtacattcagcagctggctcaagagtacagcggagactgcaagaca tcatttgacgaactctccaagattatccagaaagtgcttgcatctcgtaaagagctcctg gagtatgatctgcagcagagagaggctgctaccaagtcgtcccgaagcagtagcagccat cagcccactttcaccgccagtcagtaccgtgccctctctgtgctgggctgcggccacacc tcctccaccaaatgctatggctgtgcctcagctgtcacaggtcactgtatcacactgctc cgtgcactggccactaacccagccctccggcagatcctggtcctccagggactcatccgg gagctgtttgagtataacttgcgacgtggtacagcagccatgagggaagaagtgcgccag ctggtctgtctcctcaccagagatcatccagaagccactcagcagatgaatgacctcatc atcgctaaggtgtcagctgcccttaaaggtcactgggccaatcctgacctggttagcaat ctgcagtatgagatgctgctgctgacagactcaatttcaaaagagggaggatgctgggag ttgcggttgcgttgtgctctcagtctgttcctcatgtcggtgaatataaagacgcctgtc gtggtggagaacatcactctaatgtgtctgagaatcctgcagaagctgatcaagccccct gctcccaccagcaagaagaacaaggatgctgctactgagtccctgaccacagtcaggccc tacagtaatgaaattcatgcccaggcccaactctggctcaagaaggatcccaaagcatcc tatgaggcttggaaaaagtgtctcccagcaagataccaggagactgtgtcgaagcctcag gggaaggcagagttgcggaagcagtacctgctggagaagtatgcgtggaagtggaagcag ttcatgaggtccagaaaaggtgaaggccttttccctcgcctgctcaaactgagtcacaac aactggctgcgacaggtccttttcacacctgccactcaggcagccagacaggcagcctgc actattgtggaggccctaacaacaatccccagtcgcaagcaacaggtcctggatctgctc accagttatcttgatgagctgagtgtggctggagagtgtgcagtggagtatctgggtctg taccagaagctgatcaagccaacacactggaaggtttacctggctgctcgtggagtcttg ccctacattggtaacctgatcaccaaggaaatagccaacctgctggctctggaggaggct acactgagcacagacttgcagcaaggctatgccctcaagagcttgactggattgctctct tcttttgtggaggtggagtccattaagcggcatttcaaaagtaggttggtcggcacagtg ctcaacggttatctgtgtctgaggaagctggtggtgcagcgtaccaaactcatcgatgag actcaggacatgctgctggagatgctcgaggacatgacgacaggtactgagtctgaaacc aaagccttcatggcagtgtgcatagagactgcaaaacggtacaacctggatgattacagg acacctgtgttcatttttgagagactgtgcagcattatctatcctgaggagaacgaggtg acagagttctttgtgaccctggaaaaggatcctcagcaggaagacttcctgcagggccgc atgccaggaaacccctacagcagcaacgagcctggcatcggccctctgatgagggacatc aagaacaaaatctgccaggactgtgacctggtggcgcttcttgaagacgacagtggcatg gagcttctggtcaacaacaaaatcatcagcttggatctgtcagtggctgaggtctacaag aaggtgtggtgcccgacaaatgagggtgagccaatgagaatcatctatcgaatgagaggt ctgctgggagatgccactgaggagttcatagagtcactggactcaaccacagatgaggag gaggatgatgaggaggtgtacaagatggcaggagtcatggcacagtgtggcgggctggag tgtatgctcaaccggctgtctggaatcaaagatttcaaacaaggaagacatctgctcact gttttactgaagttgttcagttactgtgtgaaggtgaagatcaacaggcagcagctggtc aaaccagaaatgaacacactcaacgtcatgctgggaactctgaacctggctttagtggca gagcaggagagtaaagacagtggtggagcctctatagcggaacaagttctgagcatcatg gagatcattcttgatgaagccaatgcagagatttcagaggacaagggtaacctgctgctg acaggagacaaagatcagctgatcatgttgttggaccagatcaacaccccgtttgtgcgc tccaaccccagtgtgctgcagggtctgctgcgcatcatcccatacttatcctttggtgaa ctggagaagatgaggatcttggtggaacgcttcaaaccatgttgcagctttgacaagtat gacgaggagcacagtgcagatgacaaagtgtttttggattgcttctgtaaaattgctgct ggtatcaaaaataacagcaacggccatcagctgaaagatcttattctccaaaagggaatc acacagagtgcactggactacatgaagaaacatatcccaaatgccaaaaatctggatgca gatgtctggaagaagttcctctccagaccagctctaccctttattctcagattgcttcgt ggtttggcgacccagcacccccccacacaggtgctgataggcacagactcaataaccaac ttgcacaagctggagcaggtatccagtgacgaaggcatcggcactctggcagagaacctt ctggaggccctgagggagcacagtgacgtcaacctgaagattgaagcagcgcgcagggag accagagctgagaagaagcgaatggctatggccatgaggcagaaggccctgggaacactg ggcatgacgaccaatgagaagggtcaggtggtgactaagacctcactgttgaagcaaatg gaggagttgatagaggagccgggcttgacctgctgtatctgtagagaaggttacaagttc cagccaaccaaagtcctgggtatctacactttcacaaagcgtgtggccttggaggacttt gaaaacaagcctcgcaagcagcagggctacagcactgtgtcgcactttaacatagtccac tatgactgccatctggcagctgtcaggctggcccgggggcgagaggagtgggagagtgct gctctccagaatgccaacaccaagtgcaatgggctgcttcctgtgtggggaccacatgtc ccagaatcagcctttgctacatgcttagcaagacacaacacatatctgcaggagtgcaca ggccagcgggagcccacctaccaactaaacatccacgacaccaaactgctgttcctccgc ttcgccaccgaacagtcgttcagcgtggacacgggaggaggaggccgagagagcaacatc cacctcatcccctacatcatccacactgtgctctacgtcctcaacactacaagggctacg tctcgggaggagaagaacctgcagagtttccaggagcagccgtgtgagaaatggatggag agctcatatgaggttgaaggaccgcactatttcaccatcttggccatgcacatcatgccg cctgaacgctggaggagttcacgtatatacttcctacgtagactcctggtcaccgcacat gcccgcaaggtctcgggcgtttgcaccaacaaacttacagacaaagcaccaaaggaatat gcagtgtatcgctctcctcttctcttctggggcctggtggatctcgtctatgacatgttc aggaaagtacccaccagcaacactgaggggggctggtccttctcgctggcagaatatgtc cgtcacaacgacatgcccatctatgaggcctcagagcgcgtgctcagggccttccaggat gagctcatgcctgccgagtccttgtcagagttctttgatgttgtaggtcttctctctgaa atcgcagacccagacctcttcctgcaggatttgttgaactctttgccgtga

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