Seriola dumerili (greater amberjack): 111233166 Help Entry 111233166         CDS       T05606                                  Name (RefSeq) obscurin-like   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism sdu  Seriola dumerili (greater amberjack) Pathway sdu04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:sdu00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     111233166  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:sdu01001]     111233166   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:sdu04131]     111233166 Enzymes [BR:sdu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      111233166 Protein kinases [BR:sdu01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    111233166 Membrane trafficking [BR:sdu04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     111233166 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase PK_Tyr_Ser-Thr Ig_5 Ig_4 Izumo-Ig SOS1_NGEF_PH C1-set Ig_CD22 RhoGEF C2-set_2 Ig_6 V-set_CD47 ABC1 Kdo fn3 Kinase-like IQ_SEC7_PH IQ PH APH RHG20_PH DUF7283 Lep_receptor_Ig Motif Other DBs NCBI-GeneID:  111233166 NCBI-ProteinID:  XP_022616679 LinkDB All DBs Position Unknown AA seq 5487 aa AA seqDB search MGDNKPGGIIAAAKNRLQVVRGLEDVEVSECESCTFEVTLNLAYIEGVWTRDGMQLKSKP NCRISMHGKKHSLILKRVALGDAGQFSFQANGIQTAGRLSVRARDIHIMKELEDVDTMER QPVTFLCEVNQVDVDGRWYRDDCRIRPGDNIKIRHQGKTHTLLFRSVRPEHAGEIRFTAE RVSSYATLTVQELPVQIVRPLKVKIAMYHHRGLLECQVSRPNAQVRWYKNRKELLPSTKY QVISQDVYRQLTIDNVCSSDEDTYTCDAGDDKTSCQLLVEEQAISIVRGMSAVEVMEPEP ALFHVETSLKSGRPPKWTLNGEVLEPCAAVNIDREGTLHSLCLTSTESSMSGPVLFVAGK SRSTAQLTVKERPLQVLHHLDDVEAKENSSVTLSCQFAPSPRVVRWFKGRTALKTSNKYS MKREGKRAGLTIHGLTAMDSGQYRCMAGGSQSTAHVKVEARTLKLVKHLEPVEIEEDGVA TFSCELNYVVANVEWLLNNVRLYSNAINRIQHMGTMHSFIIKKLRPQESRVTFKAGLLSE TTTLRVKERPAVFLRSLEDAVGEEQGEVCLQCEISKEMVTPVWRKDGMVLTADDKHEILQ FGKSMALIVHSLSKDDAGQYTCDLGTSHSKAKVTVHDLHITIVQRIKTTSVLEGESCTFE CLLSHDLDDEPLWSINGQVVAADNRVQVINNGRKYKMTIKDALLTDAGDVVFTINDLSCR TMLFVKEKPMHIFRDLLNVKAVPGEDAELSCEITKPEATIHWLKNGHLIRKSPKYEMSVE KNLARLVIKNTTIRDSGEYCCEAEGVASRAKLEIRELQHTFARELRETRAEEKGKVTLEC ETRRPAKRVKWLKGMMDLRSGRKYVIRQKGVVLSLTITCLEKSDTDVYTCDVGTMQSRAQ LTVQGQKVLILDELEDVECLEGDTVTFRCRICPSDYIGVRWYLDETLLYTNELNEIQMVP GGYHTLTFKQLARKDTGTISFSAGDKRSYASLLVRERRPTIIKALEDCEAIEGGGLVLSC VTSKPCHILWYKDGCLMWSSSRYFASRSGCEARLTIREVCNSDAGVYECSAGSVTTRAVV TVKAIPAEFTQPLKTVEAKEGETVTLTCEYSLPGVQFHWRKGFESIRPGDKYMMKQRKTI NSLTIKGVKPEDSGEYTCQCRDHRTTASIKIHAIPISFIQQLKNMQAEEGNNVILRCELS KPGIPVEWRKGDELLKNGVKYQIRKWETTLELLIWKPVPQDTLPVTFKQKLRNVQIEEGN TATLRCELSKPGHTVEWRKRGDELIRNGEKYHIRQRDLLIELRIFDVTPEDSNIYTCICG NIETTATLTVNALPITFKQKLKNLQVEEGHNITLYCEISKPGVPVEWRLSGDLLENGEKY QIKQRASALELTIRDTVPEDSGVYTCVCREQKTKATVKVIAVPATFKVSLKSQEAEEGNS VTLRCELSKKGVPLQWQREGQELSEELSQGKYQMKVEGKTALMTILSVQPEDAGKYSCIT GDEKTTAEIKVKPLPVTFKREIQRLVAREGESGVFCCELSKPAAPVEWRKGRVILKPGEK YEMKQEGRLTKLVINNLEESDAGKYTCKTKDSQSTAELTVQALPPSFKLPLVNQEVMEGN SVVLRCELTKPAPSVEWRRGGELLKNGDRYQMRKKDLQVEMKIVDLSLDDTGDYTCICGE ERTTARIMVNERPIKFLQELKNIQVQEGNVVSLCCELSKPDTPVQWKKGDNVLTGGEKYQ MKQNGSTLELLIRKSQPEDSGTYSCVSIPVTFKQKLKNQEAVEEGSVTLRCELSKPGVPV EWRRDAQLLIEGEKYQMKQEGRVAEMLIKNLTLTDTAEYCCFAGTVVTSADIKVRELPVT FKQEVETLEVKEGESGVFCCELSKPGAPVDWRKGRVILKPGYKYEMKQEGRLTKLIINNV EESDAGKYTCKTKDSQSTAELSVKAPPITFKTKLRNLQVEEENSLTLSCELSKPGLSVEW RKGEELLKNNFKYQIKNRNSVMELTVKNAQLEDSGVYSCIYGDAKTAANVTITSIPLTFK MGLKNQEAPEGGIVTLRCELSRAGVPVQWWKSEDQLYHGGRYQMMLRGKVAEMHIKNIQP EDVGEYSCVFGGQRTVAEVNVRAAAGVFFEKELENQVVMEGKPVLLSCEVTSANVPVTWK KDNIVVEEGGRCILKKKGPTHSLEIKKLLLEDAGEYCCSTRGKKTTAKLTVRERVRIVTE LQDITVTAGEDAAFVCELSHSDVSEGVWWLGSSPLQRNEMNQMMCQGRQHRLVLTMTTPE ETGTVAFVIGDERTSACLLVVPKPKELPPFFQEELQNTEVEEGGLASLYCELSKLGVPIQ WKKNRLPLRASRKYEMKQDGCLLQLHIKELKLEDSGSYTCQAGSAETTATVTVKELPPYF KKQLRRMEAEEGGSASLSCELSKPGVSVQWKKNRLPLRESRKYEMKQDGCFLQLDIKELK PEDSGCYTCQSGGAETTATVTVKELPPFFKEELQNVKEEEGGSVSLCCEVSKPGLSVQWK KNKLPLRPSRKYEMKQDACLLQLHIKELKPEDSGSYTCQAGSAETTATVTVKVQWKKNRL QLRASRKYEMQQDGCFLQLHIKELKPEDSGSYTCQSGTAETTATVTVKELAPFFHKELQN VEAEEGGAASLHCELSKPGVSVHWRKNKLPLRANKKYEMKQDGCFFQLYIRELKPEDSGS YTCQVGSAETTASVTVKELPPFFKKDLQSMDAEEGGSAPLCCEVSKPGLSVQWKKNRLLL RASRKYEMKQDGCFIQLHIKELNPEDSGCYTCQAGSAETTATVTVKELIPFFKKELKNVE AEEGEAASLSCELSKPGVSVQWKKNKLPLRANRKYEIKQDGCLHQLHIKELKSEDSGSYT CQVGSAETFAMVAVKALQSAPPNTEPPTILPRVKGAVSKTTPSPESEEPGLPEAKPVPPE PKKRSHRKASITNSEKDEEPVLHLKQSVLKENNKDQKGTQPVKPMEKDFDVVQNITQLES EGYKKADNSVRLLEQDDRIDRKVKEPGRSMETENEVFLEKQQGRNLEEMVKADLKVSQSE RVLGDTVAEQQRLKQAGKPSEKTSEIQEKVKHPGTLLRKNKIDISIEDEPQMQEAAVKIQ AAFKGYKTRKDMRPVFKEVFKNQSADLHGTITLVCVVEGKPSTVRWLKNGQQITNDQRCR TETTEKGVCTLVIKNLTTSDGGIYTCEVVNKFGVTSYNGNVTVVQPQQAAPTAQKPVHPP LAAITPLQLAPPRPEVQAKTQTLNLPQTQAQIPTSATDAANYVESVSVSLWEAYNLTELT AQMTLEERRRSSLIAASSRAHEGRMRTPSPKHHRAHTPLASTVSGSESEGEEDSRETFEM YVARADCSPNSGNKNSFILKEGQFVEVLDSVHPDRWLVRTKPTKTNPARQGWVCPAYLEK KRKETFPQMRAPQEDLDGIGSTGEEYRRAMSQLIQGLIDGEEEFVKEMKMFTSHQLNYLD SSCHVPINILNQREIIFRNIKDIVFLHERCVLPGLRGCATDDDVAMHLIKHTEDFEKYLH YMVGQAQAEACVTDKATQQYFKELAESGKPDAPVMDVLTFLQRPVERIQTYQALLKEFIK NKAKGGQSCCLLEDAFSTVSCLPWRSDNLHQVSLIENYPAPLTALGEPVRQGVFTVWEES PEIKTASRGHQRQVFLFKECIVLCKLKRDTRMNSDTYTFKNKMKLNDVEIKETVGGDEKS WGLWHEHRGSMRRYTLQGRSTLVKLPWLKDLKELQQRSSLPTNSPPVFESLLSDCTTKIG QTIKLTCKVTGSPKPVVSWLKDGLPLEDDPRHIITADRSGTCSVILDNLTAEDSGQYTCY ATSSMGTAGTLAKVVVQAPPRFVSRLESACLIEGEDIQFSCSTLSTPLPRIRWLKDGREL TDQQKYSILNDARSGILCLTVICATAADIGQYECELTLHSYEHKMVMCWAGAPFAPMQEW ACTHVLLMCLALVDADSEGWSTAFVKKWLQTDFSPTSIAKVLFPPGHPEQAECSTEETAP AATSMDQVVQQPLYYLEEEEEEIYISEPMQEITDAPPSIQVPTEDLCVEPGQPATFTAII TGRPTPKIQWYKDEEELAANENVEIVQLGARCSVTIVCSEGEDSGIYTCLAYNDSGHASC QAQLTVEEGPLECQEREVELGKRRKLFSVYDVHEEIGRGTFGVVKRVVHRRTGEVFSAKF LPLRSSTRTRAFQERDLLSRLAHPRVACLLDFFCTRRTLVLITEICCSHGLLDHLLLRGS VSEREVQSYIQQILEGVGHIHSMNILHLDIKPDNILMVYPPRDEIKICDFGFCQEIDASR HQYSMFGTPEFVAPEIVHQEPVTVATDIWAVGVIAYLCLVCRCPFVGETDRATLLRVGEG TLNWDAPDVTYRSPEAQNFLHLVLQPDPEMRPSAFECLSHEWFQDKHTGEDTDEINMRSL KVFISKMKWQRSLTCIGSVLTLRPVPELLDAPLRETAVTVPRELQEHSSTSLSSGSSSEY DEADALDFFRHYSPTEEEEEETEEDYDPLMERAQIPEPFAKLHQDGEEEEEVTLGEEEDG EMVGRTSVLERSMSRQSVALSKDSSQSLYLSDWDEGSGSDGGRIPRGSVIRSTFYSTSHQ LSPMSARHMSLRDKFQAKKQERGRKPLRRSFSGRLNEPLIEYVEDETETNRGQRRGSIQP TMQKSCSFDSGVGLIHGNVPPHRRSRSLDEYSRRSPSSPKRTMPGEEEGSQSLKEDFTDD EVAGRNLLAIPGPRRPARRRGSITPVHATRTLGGTTVPTDFLAGDRTGTRLIQDQTESDT FAGSQGSLAESSILEHGGSESSSRIGSCEELSHGHLRGRYRSGESEGYDDQGEPLISSSP CSFQEVKPRGSFPQAPPRNRTRSNPNLSANSRGQQGPLLMPSPSPSLSSLQAPERPPRAR DKKEGYGLQRHASAPALEARPPTGKSPKLGLLKIFRRQSWTGHSYSQLEDTELGPTLGEI MTPDTPTMSLRKKMRASASSLTKLFSRSKEDVSKGGPIVKGSPPIPPERERSAGLESPKK KTSKILPSFKIPAFKKTKDLPVRPNKPEVLQLDGGRVLLVWKPIQSSDPLTYCVQFCSDG GAWTVLSDNVTDSCYVVKDLVRGASYVFRVGCITKTGAGPFSDASAPVVMATHPEETHIS LTLTETLGSKVTGSEQQTTQRNYSFLSEINRGRFSVITLCRDVETSKVFAAKITPYQAEQ RQLVLREYQLLKRLHHPHLVQLHTAYLTSYYLVLVEELCPGKELLYSLAARDLYAETHVA ELLVQILSAVDYLHSRRVIHLDLKSDNMLVDDGNHLKIVDFGSAQSYTPGQPLNIEHIQG LSESKVYIVLPKAPEILEGQGVGPETDVWAIGVLSFIMLSADSPFHAELSWEQDRNIKKG KIQFGRCYPGLSEGALNFMKTSLNNKSWGRPTAAECLQNPWLRAPRAPHKARQSKVCFST DKLKAYLNQKEEKRDLVHTKLQGPFFQ NT seq 16464 nt NT seq  +upstreamnt  +downstreamnt atgggagacaacaaacctggaggaataatagcggcagcaaagaaccggctgcaggtggtg aggggtctggaggatgtggaggtgtccgagtgtgagagctgcacctttgaggtgaccctg aacttggcctacatcgagggtgtgtggaccagggatgggatgcagctcaagtctaagccc aactgtcgcatcagcatgcatgggaagaaacactccctcatattgaagagggtggctcta ggtgacgctggccagttctcttttcaggctaatggcattcagaccgcaggtcgactcagt gtgagagctagggacatccatataatgaaggagctggaggatgtagacacaatggagcgg caacctgtgaccttcctgtgtgaggtcaaccaggtggatgtggatggtcggtggtacaga gatgactgcaggatccgacctggggacaacatcaagatcagacaccagggtaaaactcac accctgctcttcaggtcagtcaggccagagcatgctggagagatcagattcactgcagag cgtgtctcatcctatgcaactctcacagtacaagagctcccagtccaaattgtgcgtcct ctgaaggtcaagatagccatgtatcaccaccggggtctactggagtgccaggtgtcacgg cctaatgcacaggtcaggtggtacaagaacaggaaggagctcctgcctagtacgaagtac caagtcatcagccaagatgtctacaggcagctgaccatcgataatgtctgctcctcagat gaggacacctacacctgtgatgcaggagatgacaaaacctcatgtcagctcctggtagag gagcaggctatcagcatagtgcgggggatgagcgcagtggaggtgatggagccagagccg gcattgttccacgtggagaccagcttgaagtcagggaggcctccgaagtggaccctgaac ggtgaggtgctggagccatgcgcagcggtgaacatcgacagggagggcaccctccacagt ctctgtctcacctccactgaaagctcaatgtccggccctgtgctctttgtagctggaaag agtcgctccaccgctcagctcactgtgaaagagcgacctcttcaggttcttcaccacttg gatgatgtggaggcgaaggagaacagctctgtgactctgagctgtcagtttgccccttct cccagggtggtgcggtggtttaaaggtcgaactgctctgaagacttcgaacaagtacagc atgaagagagaggggaaacgagcagggctgaccattcatggcttgacagcgatggattca gggcagtaccgctgcatggctggaggttcacagagcacagcacatgttaaggtagaagca cgaacacttaagttggtcaaacaccttgagccggtggaaattgaggaagatggagtcgcc actttctcatgtgagcttaactatgtggtcgccaacgtggagtggcttctcaacaatgtc cgcctctattccaacgccatcaacaggatccagcacatgggcacaatgcacagcttcata atcaagaagctgcggccacaggagagcagggtcaccttcaaagcaggccttctctctgag actacaaccttaagggtcaaagagcgcccagcagtgttcctgaggtctctggaggatgca gtaggcgaagagcaaggggaggtctgcctgcagtgtgaaatttccaaagagatggtcacc cctgtttggagaaaggatggtatggtcctgacagctgatgataaacatgaaatactccag tttgggaagtccatggcgctgattgtccattcactgagcaaggatgatgctggacagtac acctgtgacctgggcaccagccattctaaggctaaagttacagtacatgatttacacatc acaattgttcaacgtataaagacaacctcagttctggagggtgaaagctgcacctttgag tgtctcctctctcacgatctcgatgatgagcctctctggtcgatcaatggccaggtggtg gccgctgacaaccgtgtccaggttatcaacaatggccgcaagtataagatgaccatcaaa gatgccttacttactgacgctggagacgtggtcttcacaattaacgacctcagctgtagg accatgctttttgtaaaagagaaaccgatgcacatcttcagggacctgctgaacgtcaag gcagtgccaggcgaggacgctgagctgagctgtgaaatcaccaaaccagaggccaccatc cattggctgaaaaatggccatctaatcagaaagagccctaaatatgagatgagtgtggag aagaacttggcgcggttggtgatcaagaataccaccattagagactctggggagtactgc tgtgaggccgaaggtgttgcctctcgtgccaagctggagatcagagaactccagcacaca tttgcaagggagctgagggagacacgagcagaggaaaagggtaaagtgaccctggagtgt gagaccagacggccagccaagcgtgtgaaatggctgaaaggaatgatggacctgaggtct ggtaggaagtacgtcatcaggcagaagggtgtggtgctgtccctgaccatcacctgcctg gagaagtcagacacggatgtttacacatgtgatgtcggtaccatgcagagccgagcacag ctgactgtgcagggccagaaggtattgatcctggatgaactagaggatgttgagtgtcta gaaggtgacacggtcacattcagatgtcgaatctgtcccagtgactacatcggggtcagg tggtacctggatgagactctgctgtacaccaatgagctcaatgagattcagatggtaccc ggaggctaccacaccctcacgtttaagcagcttgcccgcaaagacactggcaccatttca ttttcagcaggggacaaaagatcgtacgcttcactactggttagagagaggcgccccacc atcattaaagcactggaagactgtgaggctattgaaggaggtggtttggttttgtcctgt gtgacctccaagccatgtcacatcctctggtacaaagatggctgcctgatgtggagctcc tccagatattttgccagtcgttccggctgtgaggctcgactaacgatccgggaggtctgc aacagtgatgctggggtgtacgagtgcagcgctggatctgttacaactagggctgttgta actgtcaaagccatcccagcagagttcactcagcctctgaaaactgtggaggccaaagag ggagagactgtaaccctgacctgtgagtactctttgcctggggtccagttccactggagg aaaggtttcgagagtatcaggcctggagacaagtacatgatgaaacagaggaagacaatc aactctctaaccatcaaaggcgtgaagccggaggactcaggagaatatacctgtcagtgc cgagatcaccgcacaacagcaagcatcaaaatacatgctattcctatttcattcatacaa caactgaagaacatgcaagcagaggagggcaacaatgtcatattgcgctgtgagctgtcc aaacctggaataccagtcgaatggaggaaaggagatgagctgctgaagaatggggtcaag taccagataaggaaatgggaaaccacattggagcttctgatatggaagcctgtgcctcag gacaccctcccggtcactttcaagcagaagctgaggaatgtgcagatcgaggagggcaac acagcgactttacgctgtgagctgtctaaacctggtcatactgtggagtggaggaagagg ggggatgaactcatcaggaatggagagaaatatcacattcggcagagagacttgctgatt gaattgaggatctttgatgtgacacctgaggacagcaatatctacacatgcatctgtgga aatatagagaccactgcaactctgactgtgaatgctcttcccatcaccttcaagcaaaag ctgaagaacctccaagtcgaggaaggacacaacatcacattgtattgtgagatctctaag cctggagtcccagtggagtggaggctctcaggagatcttctggagaacggagagaagtac cagattaagcagagggcctctgctctggagttgactatcagagatactgtgcctgaagac agtggtgtatacacctgtgtgtgtagagagcagaagacaaaggccactgttaaagttatt gcggttcctgccacatttaaagtgagcctgaagagccaggaggccgaagaagggaacagt gtgacgttacgctgtgagttgtcaaagaagggagtcccattgcagtggcagagagagggc caggagctctctgaggagctatctcaaggaaagtatcagatgaaagtagaaggaaagaca gctctgatgaccatcctcagtgtccaaccagaagatgcagggaagtacagctgcatcaca ggagatgagaaaaccacagctgaaatcaaagtgaaaccacttcctgtgacattcaaacga gagatccaacgcctggtggcgagggaaggggagagtggagttttctgctgtgagctctcc aaacctgcagctccagtggagtggaggaaaggcagagtcatcctgaagcctggagagaaa tatgagatgaagcaggagggacgtctcactaaactggtcatcaacaacttggaggagagc gatgctgggaaatacacctgcaagactaaagacagccaatcaactgctgaactcaccgta caagctttaccgccaagtttcaagctgccgctagttaaccaggaggtgatggaggggaac agtgtggttctgcgctgtgagctcaccaaacctgccccatcggtggagtggaggagagga ggtgagctgctgaagaatggagacaggtaccagatgaggaagaaggacctccaggtggag atgaagattgtggacctcagtctggatgacactggagattatacctgtatatgtggagaa gagaggacaacagctaggatcatggtgaatgaacggcccatcaaattccttcaagaactg aaaaatattcaggtgcaggagggcaatgtggtgagtctctgctgtgagctctccaaacct gacactcccgtgcagtggaagaaaggagacaatgtgttgaccggcggagagaaataccag atgaagcagaacggctccacactggagctcctcatcaggaaaagccagcctgaggacagt ggcacatacagctgtgtttcgatcccggtgaccttcaagcagaagctgaagaaccaggaa gctgtggaggagggcagtgtgacgctgcgctgtgagctttctaagccaggagtcccagtg gagtggaggagagatgctcaacttctgatagagggagaaaaatatcagatgaagcaagag ggcagggtggccgagatgctgattaaaaatttaactctcacagacactgcagagtactgt tgttttgctggcactgttgtgacctcagctgacatcaaagtaagagagctccctgtaaca tttaaacaagaggttgagactttggaagtgaaggaaggggagagtggagttttctgctgt gagctctccaaacctggagctccagtggactggaggaaaggcagagtcatcctcaaacct ggatacaaatatgagatgaaacaagagggacgtctcacaaaactgatcatcaacaatgtg gaggagagcgatgctgggaaatacacctgcaagaccaaagacagccaatcaactgctgag ctcagcgtcaaggctcctcccatcacgttcaagacgaagttaaggaacctgcaggtggag gaggagaacagcctgacattgagctgtgagttatctaagcctggcctttctgtggagtgg aggaaaggagaagagcttctgaagaataatttcaagtaccagattaaaaaccgaaacagt gtcatggagctgaccgtcaaaaacgcacagctggaggacagtggtgtctacagctgtatc tatggtgatgccaagaccgcagccaacgtcaccattacatctattcccctcacctttaaa atgggtctgaagaaccaggaggcccctgaaggaggcatcgtgacccttcgctgtgaactg tccagggccggggtgcctgtgcagtggtggaagtcagaggaccagctctatcatggaggg aggtatcagatgatgctgagagggaaggtagcagagatgcacatcaaaaacatccagcca gaggatgttggagagtacagctgtgtctttggagggcagaggacagtggctgaagtgaac gtgagagcggcagcaggtgtgttctttgagaaggaactggagaaccaagtggtaatggag gggaaacctgtgctgctgtcttgtgaagttaccagtgctaatgtccctgttacttggaag aaggacaacattgtggtagaagaaggaggacggtgcattttaaagaaaaaaggccccacg cactctctggagatcaagaaattacttctggaggatgctggagagtactgctgtagcacc agaggcaagaagaccactgccaagctgactgtgagggagcgcgtgcggattgttacagag ctgcaagacataacggtgacggcgggagaggacgcggcgtttgtgtgtgagctgagccac tcggacgtgagtgaaggtgtctggtggctcggttccagcccactgcaaaggaacgagatg aaccagatgatgtgccagggtcgccagcaccgactggtcctcaccatgacaacacctgag gagacgggcaccgtggcatttgtgattggggatgagaggacctctgcatgtctgctagtg gtccctaagcccaaagagctccctccattcttccaggaagaattgcagaatacggaagtt gaggagggaggtttggcctctctgtactgtgagctgtctaaacttggagtgccaattcaa tggaagaagaacagactgccgctaagagccagcaggaaatatgagatgaagcaggacggc tgcctcctccagctgcacatcaaggagctcaaacttgaggacagtggcagctacacatgt caagcaggaagtgcagagaccactgcaactgtgacagtgaaagagctccctccatacttc aagaaacaattaagacgcatggaggctgaggagggaggttcagcctccctctcttgtgag ctgtctaaacctggagtatcagtgcagtggaagaagaacagactgccactcagagaaagc aggaagtatgagatgaagcaggacggctgcttccttcagctcgacatcaaggagctcaaa cctgaggacagtggctgttacacatgtcagtcaggaggtgcagagaccactgcaactgtg acagtgaaagagctcccaccatttttcaaagaggaactgcagaatgtgaaggaagaagag ggaggttcagtttccctgtgctgtgaggtgtccaaacctgggctgtcagtgcaatggaag aagaataagctgcctctaagacccagcaggaaatatgagatgaagcaggatgcctgcctc ctccagctgcacatcaaggagctcaaacctgaggacagtggcagctacacatgtcaagca ggaagtgcagagaccactgcaactgtgacagtgaaagtgcaatggaagaagaacagactg caactgagagccagcaggaagtatgagatgcagcaggacggctgcttcctccagctccac atcaaggagctcaaacctgaggacagtggcagctacacatgtcagtcaggaactgcagag accactgcaacggtgacagtgaaagagcttgctccattcttccacaaggaattgcaaaat gtggaggctgaggagggaggtgcagcctccctgcactgtgagctgtctaagccaggagtg tcggttcactggaggaagaacaagctgccactgagagccaacaagaagtatgaaatgaaa caagatggctgcttcttccagctctacatcagggagcttaaacctgaggacagtgggagc tacacatgtcaagtaggaagtgcagagaccactgcatctgtgacagtgaaagagctcccc ccattcttcaagaaggacttacaaagtatggacgctgaggagggaggatcagctcccctg tgctgtgaggtgtctaaacctgggctgtcagtgcaatggaagaagaacagactgttactg agagccagcaggaagtatgagatgaaacaagatggctgcttcatccagctacacattaag gagctcaatcctgaggacagtggctgctacacatgtcaagcaggaagtgcagagaccact gcaactgtgacagtgaaagagctcattccattcttcaagaaagaactaaaaaatgtggag gctgaggagggagaggcagcctccctgtcctgtgagctgtctaagcctggagtgtcagtg caatggaagaagaataagcttccactgagagcaaacaggaagtatgagataaaacaagat ggctgcctccaccagctgcacatcaaggagctcaaatctgaggatagtggcagctacaca tgtcaagtaggaagtgcagagacctttgcaatggtggcagtgaaagcactacaatctgct ccaccaaacacagagcctcccacaatattacctcgggtaaagggtgctgtctctaaaaca actcctagtcccgagagtgaggagcctggcctcccagaggccaaacctgttcctccagag cccaaaaagagatctcataggaaagcatctattacaaattcagaaaaagatgaggagcca gtattgcacctaaagcagtctgtgctgaaggaaaataataaagaccaaaaaggaacccaa cctgtaaagcctatggagaaagactttgatgttgtacagaacataacacaactggagagt gagggctacaagaaagccgataactcagtgagattactagagcaggatgacaggattgac aggaaggtcaaagagccagggaggtctatggaaacagaaaatgaagttttcctggagaag caacaaggaaggaatttggaggaaatggttaaagctgaccttaaagtaagtcaatcagag agggttctgggtgacactgtggctgaacaacagagattaaaacaagcaggaaagccctca gagaaaacaagtgaaattcaggagaaggtgaaacatcctgggacgcttctgcggaagaac aagattgacatcagcattgaggatgaaccacaaatgcaagaggcagcagtcaagatccag gctgcctttaaaggctacaaaacccgcaaagacatgcgacctgtctttaaagaggttttt aagaaccagagtgcagatcttcatggtacaattactctagtgtgtgttgtagaaggaaaa cccagcacagtgcgctggctgaaaaacggccaacaaatcactaatgaccagcgctgccgt actgagactacagagaagggcgtgtgcacactggtgatcaaaaaccttaccaccagtgac ggtggaatctatacctgtgaggtggtgaataagtttggtgtgacctcctacaatggaaac gtaacggtagtacagcctcagcaggctgctccgacagcccagaagcctgtgcacccaccc cttgcagccataactcctctgcaacttgccccaccaaggcctgaggtccaggccaaaaca cagactctgaatcttcctcagactcaagcacagatacccacttcagctacagatgctgca aactatgtagaaagtgtgagtgtctctctgtgggaggcctacaacctgacggagctgact gcacagatgactctggaagagaggagacgatcatcactcattgctgccagctccagagct catgaaggcagaatgaggacaccatctccaaagcaccatcgtgcccacacacccttagca agtacggtatctggatcagagtcagagggggaagaggatagcagagagacatttgaaatg tatgtggctcgagctgactgcagtcctaacagtggaaataagaacagtttcatcctgaag gagggccagtttgtagaggtcctggattctgttcatcctgacagatggctggtgaggacc aaacccaccaaaaccaaccctgctcgacagggatgggtgtgtccagcctacctggaaaag aagagaaaggaaaccttcccacaaatgagagcacctcaagaggatcttgatggaataggg tctacaggagaagaatatcggagagctatgagccaactgatccaaggcctgattgacgga gaggaggagtttgtaaaggagatgaagatgttcacctctcaccagctaaattatctggac tctagttgccacgtccccattaacatcctcaaccagagagagatcattttcaggaatatc aaggacattgtctttctgcatgagaggtgcgtccttcctggtctgagaggctgtgccaca gacgatgatgtggccatgcatctgatcaagcacactgaggactttgaaaagtatcttcac tacatggtgggacaagctcaagctgaagcctgcgtcaccgacaaggctacccagcaatat ttcaaagagttagcagaatctggtaagcctgacgcacctgtcatggatgtccttaccttc ctccagcgaccagtggagaggattcaaacctaccaggctttactcaaggagtttatcaag aacaaagccaaaggtggtcagagctgctgtctgttagaggatgccttctctacggtgtcc tgtctgccctggaggtctgacaacctgcatcaagtgtccctcatcgagaactacccagct cctctaactgccctgggcgagcctgtgcgacagggagtcttcacagtgtgggaggaatct ccagaaattaagacggcctctagagggcatcagagacaagtctttctcttcaaggaatgt atcgtactgtgtaaactgaaaagggacactcgcatgaacagtgacacctacaccttcaag aacaaaatgaagctgaatgatgtggaaataaaggagactgtgggtggagatgaaaagtct tgggggttgtggcatgagcacaggggctcaatgcgtaggtacacactgcagggccgctcc acgctggttaaactgccctggctcaaagacctgaaggagctccagcaacgctccagtctg cccactaacagcccaccagtgtttgagtcactgttgtctgactgcacaacaaagataggg cagacaattaaactgacatgcaaggtcacaggatcacccaaaccagtggtcagctggctc aaagatggccttcctctggaggatgacccccgtcacatcatcacagcggaccggtctgga acctgcagtgtcatcctggacaatctcactgcagaggactctggacagtatacatgttac gctaccagctccatgggcactgctggtactctggctaaggttgtggtgcaggctccaccc agatttgtgagtcggctggagagtgcttgtctaatagaaggagaggacatccagttctct tgttccacactcagtactcctttaccacgaatcaggtggttgaaagatggcagagagttg actgaccagcaaaaatactcgatcctgaatgatgctcggagtggaatcttgtgtctgacg gtcatctgcgcaacagcggcagatattggacagtatgagtgtgagctaactcttcactcc tacgaacacaagatggtcatgtgctgggcgggtgctccctttgcgcccatgcaggagtgg gcatgcacccatgtcctgttgatgtgtttggctttggtagatgcagactcagagggctgg tccactgcctttgtgaagaaatggttacagactgatttcagccccacctctattgccaag gtgcttttccctcctggacaccctgaacaagcagagtgtagcactgaggagacagctcct gctgccacatccatggatcaggtggttcagcagccgctgtattacctggaggaagaggag gaggagatttacatctcagaaccaatgcaggaaattacagatgctccaccctccatccag gtacccactgaggacctgtgtgtagagcccggccaaccagctacatttacagccatcatc acaggacgaccgactcctaagatacagtggtacaaggatgaagaagagcttgcagccaat gagaatgtggagatagtacagcttggtgcccgctgctcagtgaccatagtgtgctccgag ggtgaggacagcggcatatacacctgcttagcctacaatgactccggccatgcctcatgc caggctcagctcacggtggaggaaggcccactggagtgtcaggagagagaggtggagctg gggaagagaaggaagttattctctgtctatgatgttcatgaggaaattggaaggggaacg tttggggtagtgaagcgtgtcgtccacagaaggacaggtgaagtcttttctgccaagttc cttcctctgcggagcagcactcggacgagggccttccaggagagagacttactctcccgt ctggctcatcccagagtggcctgtctgctggacttcttttgcaccagacgcactctggtg ctgatcacagaaatctgctgctctcatggacttctggatcatttattactcagaggatcc gtctcagagagagaggttcagtcatacatccagcaaatccttgaaggtgttggtcacatt cacagcatgaacatcttgcatctggacattaaaccggataatatcctaatggtgtatcca cccagagatgagataaagatctgtgacttcggcttttgccaagaaatagacgcatccaga caccagtacagcatgtttggtacaccagagttcgttgcacccgagattgttcaccaagaa ccagtcactgttgccactgatatttgggctgtgggtgttatagcctatctatgtctggtg tgtcgatgtccttttgtgggcgagacggaccgggcaacactgctgagagtgggggagggg accctgaactgggacgcccctgatgtcacatacaggagtcctgaggcacagaactttctc cacctggtccttcagccagatccagagatgcgaccgtctgcctttgagtgcttgagccat gaatggttccaggacaaacatacaggagaagatactgatgaaatcaacatgagaagtttg aaagtctttatctcaaaaatgaaatggcagcgttcgttgacttgcattgggtcagttctc acattgaggcctgtccctgagctgctggacgctcctctcagagagactgctgtgacggtg cctcgtgagctccaggaacacagcagcacctctctgagcagtggctcatcatctgagtat gatgaagctgacgctttggactttttccggcactacagtccgactgaggaggaggaggag gaaacagaggaggattatgatcctttaatggagagagcacagatccccgagccttttgcc aaactccaccaagatggagaggaagaggaggaagtgacattaggggaggaagaggatggg gagatggtaggaaggacgagtgtattagagcggagtatgagcaggcagtcagttgcgttg agcaaagacagcagtcaatctctctacctctctgactgggatgagggttcaggaagtgac ggaggtcgtatccctcggggcagcgtcatccgaagcactttctacagcacctctcatcag ctttcacccatgtctgccagacacatgtcattacgggacaaattccaggccaaaaaacag gagagaggtcgcaaaccactgaggaggagcttttcaggacgcctcaatgaacctcttatt gaatatgtggaggatgagacagaaactaatcgaggccaaagacggggatctattcagccc acgatgcagaaatcctgctcctttgacagtggagttggcctcatccatggcaacgtaccc cctcacaggaggagcaggtctcttgatgagtattcgcgccggtctcccagctcacccaag cgcacaatgccgggggaagaagaaggctctcaaagtctgaaggaagatttcacagatgat gaagtggctgggagaaacttgttggccatcccgggcccacgacgacctgcaagaagacgt ggctccatcactcctgtacatgcgactcgcacactgggcggaacaactgttcccacagac ttccttgctggagacagaacgggcaccaggttgattcaggaccagacagagagcgatact tttgctggctcccaggggtccctggctgagtcatctattttggagcacggtggctcagag tcttcaagcagaatcggctcctgcgaggagctgagtcatggtcatctcagaggaagatac agatcaggagagagtgaagggtatgatgaccagggggagcctctgatttcatcatctccc tgctcattccaagaagtcaaacccagaggctcgtttcctcaggccccaccgcgaaaccgc acccgctccaacccaaacttatctgcaaacagcagaggtcagcaagggcccctgttgatg ccgagccccagtcccagcctctcttctctccaggctccagagaggcctcccagggccagg gacaagaaggaaggctacggcctgcagaggcatgcatctgctccagccctggaagcccga ccacccacaggaaagtcacccaagctgggactgctcaagatcttccgcaggcagtcctgg actggccattcgtactctcagctggaggacacagaattaggacccacattaggagagatc atgacgcccgatacacccaccatgtctttgaggaagaaaatgagagcttcagcttctagc ctgaccaagctgttttccagatctaaggaggatgtgagtaaaggagggccaatagtaaaa ggatcacctcccatcccacctgaaagggagcgtagtgctggtcttgagagtccaaaaaag aagacctccaaaatccttccttctttcaaaatacctgcattcaaaaagacaaaagatctg ccagtccgtcccaacaagcctgaagttctgcagttagatggaggcagagtcctgctggtt tggaaaccgatccagtcaagtgaccctctcacctactgtgtgcagttctgttcagatggt ggggcgtggacagtcctgtcagacaatgtgacagacagctgctatgtggtgaaggactta gtgagaggagcgtcttatgtgttcagggtgggctgcatcaccaagacaggagcaggacct ttcagtgacgcttcagcacctgttgttatggctactcatcccgaagagactcacatttct ctaaccctgactgagaccctggggtcaaaggtcactggatcagaacaacaaacaacacaa aggaactacagcttcctctctgagattaacaggggtcgtttcagtgtaataaccctgtgt agagatgttgaaacgagcaaagtgtttgcagccaagatcaccccttaccaggcagagcag agacagctggtgcttagggagtaccagctgctgaagaggcttcatcacccacacctggtg cagctgcacactgcctacctcacctcctactacctggtgttagtggaggagctttgtccc ggcaaggagctgctctacagtctggctgcgagagatctgtacgcagagactcatgtcgct gagctgctggttcagattctgagtgcagtcgattaccttcacagccgtcgagtcatccac ctggacctgaagtctgacaacatgctggtggatgatggtaaccacttaaagattgtggac tttggctcagctcagtcctacacacccggacagcccctcaacatcgagcacatccagggc ctgtcggagagcaaagtttatattgtccttcctaaagctccggagatcctggagggtcag ggtgtcgggcctgaaactgatgtttgggctattggagttctgtcgttcatcatgttgagc gccgacagcccgtttcatgcagagctcagctgggagcaagacagaaacatcaagaagggg aagatccagttcggacgctgttaccctggtctgtcagagggagccttaaacttcatgaag accagcctgaataacaaatcctgggggagacccactgcagctgagtgtctccagaaccca tggctgcgtgctcctcgtgcgccacacaaagcccgacaatccaaggtgtgtttctccaca gacaagcttaaagcttacctcaatcagaaggaagagaaacgagacctggtccacaccaag ctgcagggtcccttcttccagtaa

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