Streptomyces durmitorensis: M4V62_05235
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Entry
M4V62_05235 CDS
T08503
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
sdur
Streptomyces durmitorensis
Pathway
sdur00270
Cysteine and methionine metabolism
sdur00450
Selenocompound metabolism
sdur01100
Metabolic pathways
sdur01110
Biosynthesis of secondary metabolites
sdur01230
Biosynthesis of amino acids
Module
sdur_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sdur00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
M4V62_05235 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
M4V62_05235 (metE)
Enzymes [BR:
sdur01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
M4V62_05235 (metE)
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Motif
Pfam:
Meth_synt_2
Meth_synt_1
B12-binding
Motif
Other DBs
NCBI-ProteinID:
UQT54548
UniProt:
A0ABY4PL85
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Position
1099867..1102188
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AA seq
773 aa
AA seq
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MTAKPAAAAARATVYGYPRQGPNRELKKAVEGYWKGRVTADALRDTAAQLRRSTWQHLAD
AGIHEVPTGDFSYYDHVLDTSVMVGAVPQRHREAVETDALDGYFAMARGTQDVAPLEMTK
WFDTNYHYLVPELGPDTVFTADSAKQVAELTEAIALGLVARPVLVGPVTYLLLAKPAPGV
AADFEPLTLLDRLLPVYAEVLADLRAAGAEWVQLDEPALVQDRTPAELNAATRAYRDLGA
LTDRPQLVVGSYFGRLGDALPVLAKAPVEGLALDFTEAAASQLEDLAAVGGLPGKRLVAG
VVNGRNIWINDLEKSLSTLGTLLGLADRVDVSASCSLLHVPLDATAERDIDPQIARWLAF
AHQKTAEIATLARGLAQGTGAITAELSANRAGLASRSGSALTHDPAVRSRVAAITGADAR
RAHAYPERAAAQRTRLGLPQLPTTTIGSFPQTTELRTARADLRAGRLDTSGYEERIKNEI
REVLAFQEKAGIDVLVHGEPERNDMVQYFAEQLTGYLATQHGWVQSYGTRYVRPPVLAGD
ISRPEPMTVRWTSYANSLTDRPVKGMLTGPVTMLAWSFVRDDQPLGDTARQVALALRDEV
NDLEAAGTSAIQVDEPALRETLPLRAADHPAYLDWATESFRLTTSGVRPDTQIHTHMCYA
EFGDIVQAIDDLDADVISLEAARSHMQVARELAEHGYPREAGPGVYDIHSPRVPSTEEAA
TLLRKGLEAIPAERLWVNPDCGLKTRGWPETKASLENLVAAAREVRAELPAGS
NT seq
2322 nt
NT seq
+upstream
nt +downstream
nt
gtgacagcgaagcccgcagccgcggcagcacgggccaccgtgtacggctacccccgccag
ggccccaaccgggaactgaagaaggccgtcgagggttactggaagggccgcgtcaccgca
gacgccctccgggacaccgcggcgcaactgcgccggtccacctggcagcacctggccgac
gcaggcatccacgaagtgccgaccggcgacttctcgtactacgaccacgtcctggacacc
agcgtcatggtcggcgccgtcccccagcggcaccgcgaggccgtcgaaaccgacgcgctc
gacggctatttcgcgatggctcgcggcacgcaggacgtggcgccccttgagatgaccaag
tggttcgacaccaactaccactacctcgtgccggagctcggccccgacaccgtcttcacc
gccgactccgccaagcaggtcgccgagctgacggaggccatcgcgctcggcctcgtggcc
cggccggtgctcgtcggcccggtcacctatctgctgctcgccaagcccgcgcccggcgtg
gccgccgacttcgagccgctcaccctcctggaccgcctgctgcccgtctacgccgaggtc
ctcgccgacctgcgcgccgcgggcgccgagtgggtgcagctcgacgagcccgccctggtc
caggaccgcaccccggccgagctcaacgccgccacccgcgcctaccgcgatctcggtgcg
ctcaccgaccgccctcagctcgtcgtcggctcgtacttcggcaggctcggcgacgcgctt
ccggtgctcgccaaggcgccggtcgagggcctcgccctggacttcaccgaggctgccgcg
agccagctggaggatctcgccgccgtcggcgggctgcccggcaagcgtctggtcgcgggc
gtcgtcaacggccgcaacatctggatcaacgacctggagaagtccctcagcacactgggc
acgcttctgggcctcgcagaccgggtcgacgtctccgcgtcctgctccctgcttcacgtc
ccgctggacgccaccgccgaacgggacatcgacccgcagatcgcccgctggctggccttc
gcccaccagaagaccgccgagatcgccacgctggcccgcggcctggcccagggcacgggc
gccatcacggccgaactgtccgccaaccgcgccggcctggcgtcccgctcgggctcggcc
ctcacccacgacccggccgtacgctcccgcgtcgccgcgatcaccggcgccgacgcccgc
cgcgcccacgcctacccggagcgtgcggcggcccagcggacccggctcggccttccgcag
ctgcccacgaccaccatcggctccttcccccagaccaccgaactgcgcacggcacgcgcc
gacttgcgtgcgggccgtctcgacacgtccggctacgaggagcgcatcaagaacgagatc
cgcgaggtcctcgccttccaggagaaggcgggcatcgacgtcctggtgcacggcgagccc
gaacgcaacgacatggtgcagtacttcgccgagcagctcaccggctacctcgccacgcag
cacggctgggtccagtcgtacggcacccgctatgtgcgcccgccggtcctggccggcgac
atctcacggcccgagccgatgacggtgcggtggacctcgtacgccaactccctcaccgac
cgccccgtcaagggcatgctcaccggtcccgtcaccatgctcgcctggtccttcgtccgt
gacgaccagccgctcggcgacacggcccgccaggtcgcgctcgccctgcgcgacgaggtc
aacgacctggaggcggcgggcacttcggccatccaggtggacgagcccgcgctgcgcgag
acgctgccgctgcgcgccgccgaccacccggcctacctggactgggccacggaatccttc
cgcctcaccaccagcggcgtacgcccggacacgcagatccacacgcacatgtgctacgcg
gagttcggcgacatcgtccaggccatcgacgacctcgacgccgacgtcatcagcctggaa
gccgcccgctcgcacatgcaggtggcccgcgaactggccgagcacggatacccgcgcgag
gcgggccccggcgtctacgacatccactccccccgcgtaccgagcacggaggaggcagcg
accctgctgcgcaagggacttgaggccatccccgccgagcggctctgggtcaaccccgac
tgcggcctcaagacccgcggctggcccgagaccaaggcctccctggagaacctggtcgcc
gccgcgcgcgaggtgagggcggagctgcccgcgggttcctga
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