Streptomyces durmitorensis: M4V62_30665
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Entry
M4V62_30665 CDS
T08503
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sdur
Streptomyces durmitorensis
Pathway
sdur00300
Lysine biosynthesis
sdur00550
Peptidoglycan biosynthesis
sdur01100
Metabolic pathways
sdur01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sdur00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
M4V62_30665
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
M4V62_30665
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
M4V62_30665
Enzymes [BR:
sdur01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
M4V62_30665
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
Motif
Other DBs
NCBI-ProteinID:
UQT59071
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All DBs
Position
6879101..6880516
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AA seq
471 aa
AA seq
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MIALSLAEIATVVGGQTYDIPDPSVQVTGPVVRDSREVEPGSLFVAFVGERADGHDYASA
VVEAGAAAVLASRPVGVPAIVVDDVQAALGALARHVVERLGATLVALTGSVGKTSSKDLL
AQVLRSKAPTVFTPGSLNNEIGLPLTALSATDETRFLVLEMGARGIGHIRYLTGLTPPKI
GLVLNVGTAHIGEFGGREQIAQAKGELVESLPADGTAVLNADDRLVRAMASRTKARVLLF
GESADADVRAENVRLTEIGQPAFTLHTPSGCSDVTLRLYGEHHVSNALAAAAVAHELGMS
ADEIARALSDAGTLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALASMGKGRRTWA
VLGHMAELGDEGLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEESVHVS
DAQAAIDLLRSELRPGDVVLVKASRSVGLERVATALLDDSASSSEGQVAGR
NT seq
1416 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccactgtcgtcggcgggcagacgtacgacata
ccggatccgtccgtccaggtcaccggaccggtcgtcagggactcccgtgaagtggagccc
ggcagcctcttcgtcgccttcgtcggcgagcgcgccgacggccacgactacgcgtccgcg
gtggtcgaagcgggcgccgccgccgtcctggcctcgcgccccgtcggcgtaccggccatc
gtcgtcgacgacgtgcaggcggcgctcggcgcccttgcgcggcacgtcgtggagcggctc
ggcgcgacgctcgtcgcgctcaccggctccgtcggcaagaccagctccaaggacctgctc
gcccaggtcctgcggagcaaggcgcccacggtcttcacgccgggctcgctcaacaacgag
atcggcctgccgctcaccgccctcagcgccaccgacgagacgcggttcctcgtcctggag
atgggcgcgcgcggcatcggccacatccgctacctcaccggcctcaccccgccgaagatc
ggcctcgtgctcaacgtcggaaccgcccacatcggtgagttcggcggacgcgagcagatc
gcacaggcgaagggtgaactcgtcgagagcctccccgccgacggcaccgccgtcctgaac
gccgacgaccggctggtgcgcgccatggcttcgcgcacgaaggcgcgcgtcctgctcttc
ggggagtccgccgacgccgacgtacgtgccgagaatgtccggctcacggagatcggacag
cctgcctttacgctgcacacaccctccgggtgcagcgacgtgaccttgcggctgtacggt
gagcaccacgtgtcgaacgcgcttgccgcggccgccgtcgcccatgagctgggcatgtcc
gcagacgagatcgcccgcgcgctctccgatgcgggcacgctgtcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgccctgcgcgcgctcgcgtccatgggcaagggacgtcgtacgtgggcg
gtgctcggtcacatggccgagctcggtgacgaggggctcgccgaacacgacgcggtcgga
cggctcgctgtccgactgaacgtgagcaagctcgtggcagtcgggggcagggaagcgtcc
tggctccaactgggcgcatacaacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggcgatcgacctgctgcgcagcgagctgcgcccgggagacgtcgtgctg
gtgaaggcttccagatcggtcggtctcgagcgggtcgccacggcgctgctcgatgactcc
gcgtcgtcgtccgaggggcaggtcgccggccgatga
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