Streptomyces davaonensis: BN159_2869
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Entry
BN159_2869 CDS
T02518
Name
(GenBank) putative AIPM/Hcit synthase family transferase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sdv
Streptomyces davaonensis
Pathway
sdv00290
Valine, leucine and isoleucine biosynthesis
sdv00620
Pyruvate metabolism
sdv01100
Metabolic pathways
sdv01110
Biosynthesis of secondary metabolites
sdv01210
2-Oxocarboxylic acid metabolism
sdv01230
Biosynthesis of amino acids
Module
sdv_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sdv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BN159_2869
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BN159_2869
Enzymes [BR:
sdv01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BN159_2869
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
PEP_mutase
HNHc_6
Motif
Other DBs
NCBI-ProteinID:
CCK27248
UniProt:
K4R1N4
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All DBs
Position
complement(3265963..3267570)
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AA seq
535 aa
AA seq
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MTETSELDDSFHVFDTTLRDGAQREGINLTVADKLAIARHLDDFGVGFIEGGWPGANPRD
TEFFARAQQEIDFKHAQLVAFGATRRAGAKAAEDPQVRALLDSGAPVITLVAKSHDRHVE
LALRTTLDENLEMVRDTVSFLKEQGRRVFVDCEHFFDGYRANPEYAKSVVRTASEAGADV
VILCDTNGGMLPAQVQAVVGTVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTA
NGYGERVGNANLFPVVAALELKYGKKVLPEGHLREMTRISHAIAEVVNLTPSTHQPYVGV
SAFAHKAGLHASAIKVDPDLYQHIDPEQVGNTMRMLVSDMAGRASVELKGKELGVDLGGD
RELVGRVVERVKERELKGYTYEAADASFELLLRAEVEGGKPLKYFDVESWRAIVEDRPDG
THANEATVKLFAKGERIVATAEGNGPVNALDRALRVALEKIYPQLAKLDLVDYKVRILEG
VHGTQSTTRVLISTSDGAGEWSTVGVAENVIAASWQALEDAYTYGLLRAGVSPAQ
NT seq
1608 nt
NT seq
+upstream
nt +downstream
nt
atgacggaaaccagcgagctcgacgactcgttccacgtcttcgacaccaccctgcgcgac
ggcgcccagcgtgagggcatcaacctcaccgtcgcggacaagctggccatcgcacggcac
ctggacgacttcggcgtgggcttcatcgagggcggctggcccggcgccaacccgcgggac
accgagttcttcgcccgcgcccagcaggagatcgacttcaagcacgcccagctggtcgcc
ttcggtgccacccgccgggcgggcgccaaggctgccgaggacccgcaggtgagggcgctc
ctggactcgggcgccccggtgatcaccctggtggccaagtcgcacgaccggcatgtggaa
ctcgcgctgcgcaccaccctggacgagaacctggagatggtccgggacaccgtctccttc
ctcaaggagcagggccgccgggtcttcgtcgactgcgagcacttcttcgacggctaccgc
gccaaccccgagtacgccaagtccgtcgtccgtacggcgtccgaggccggcgcggatgtc
gtcatcctctgcgacaccaacggcggcatgctcccggcgcaggtccaggcggtcgtgggg
acggtactggcggacaccggcgcccggctcggcatccacgcccaggacgacaccggctgc
gcggtcgccaacacgctcgccgcggtggacgcgggcgcgacccacgtccagtgcacggcc
aacggctacggcgagcgggtcggcaacgccaacctcttcccggtggtagcggccctggag
ctgaagtacggcaagaaggtcctgcccgagggacacctccgcgagatgacccggatctcc
cacgccatcgccgaggtcgtcaacctcaccccctccacccaccagccctacgtcggcgtc
tccgccttcgcgcacaaggcgggactgcacgcctccgcgatcaaggtcgacccggacctg
taccagcacatcgaccccgagcaggtcggcaacaccatgcggatgctggtctccgacatg
gcgggccgcgcctcggtggagctcaagggcaaggaactcggcgtcgacctgggcggcgac
cgcgaactggtcggccgggtcgtggagcgggtcaaggagcgcgagctcaagggctacacc
tacgaggcggcggacgcctccttcgagctgctgctgcgcgccgaggtcgaggggggcaag
cccctgaagtacttcgacgtggagtcctggcgcgcgatcgtcgaggaccgccccgacggc
acccacgccaacgaggccaccgtcaagctcttcgccaagggcgagcgcatcgtggccacc
gcggagggcaacggcccggtcaacgccctggaccgtgccctccgcgtggcgctggagaag
atctacccccagctcgccaagctggatctggtcgactacaaggtccgcatcctggagggc
gtccacggcacccagtcgaccacccgcgtgctgatctccacgtccgacggcgcgggcgag
tggtcgacggtgggcgtcgcggagaacgtcatcgccgcgtcctggcaggccctggaggac
gcctacacctacggtctgctccgggccggcgtgagcccggcgcagtaa
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