Streptomyces dengpaensis: C4B68_11455
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Entry
C4B68_11455 CDS
T06611
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sdx
Streptomyces dengpaensis
Pathway
sdx00290
Valine, leucine and isoleucine biosynthesis
sdx00660
C5-Branched dibasic acid metabolism
sdx01100
Metabolic pathways
sdx01110
Biosynthesis of secondary metabolites
sdx01210
2-Oxocarboxylic acid metabolism
sdx01230
Biosynthesis of amino acids
Module
sdx_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sdx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
C4B68_11455 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
C4B68_11455 (leuC)
Enzymes [BR:
sdx01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
C4B68_11455 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
C4B68_11455 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
AVH56292
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Position
complement(2551960..2553384)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQAGRPVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHSLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPEGVTA
KDLILAIIAKIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRAHAPEGEDWDAAVAYWKTLKSDDDAEFDAEVVIDAASLSPFVTWGTNPGQGAPL
SASVPDPASYEDASERLAAEKALEYMGLTAGQALRDIKVDTVFVGSCTNGRIEDLRAAAE
IVGGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDARTPAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccatgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccgcaggcc
ttcgacggtctgcgtcaggcggggcgcccggtgcgccgcctcgacctcaccatcgccacc
gaggatcacaacaccccgaccctcgacatcgacaagcccatcgcggacccggtctcccgg
gcccagctggagacgctgcgcaagaactgcgccgagttcggtgtacggctgcactcgctg
ggtgacgtcgagcagggcgtcgtccacgtggtgggaccgcagctgggcctgacccagccg
ggcaccaccgtggtctgcggtgactcccacacctccacgcacggtgccttcggcgcgctg
gcgttcggcatcggcacctcgcaggtcgagcatgtgctggccacccagacgctgccgctg
gcccgaccgaagaccatggccatcacggtcgacggcgaactgcccgagggcgtcacggcc
aaggacctgatcctggcgatcatcgccaagatcggtacgggcggcggccagggctacatc
ctggagtaccgcggctccgccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcgtacctgaagggccgtgcccacgcccccgagggcgaggactgggacgccgcggtcgcg
tactggaagaccctgaagtccgacgacgacgcggaattcgacgcggaggtcgtcatcgac
gccgcctccctgtcgccgttcgtcacctggggcaccaaccccggccagggcgcgccgctt
tcggcgtccgtccccgaccctgcttcgtacgaggacgcttcggagcgcctggccgccgaa
aaggccctggaatacatggggttgaccgccggacaggcgctgcgcgacatcaaggtcgac
accgtcttcgtagggtcgtgcaccaacggccgcatcgaggacctgcgtgccgccgcggag
atcgtcgggggccgcaaagtcgccgacggcgtacggatgctggtcgttccgggttccgcg
cgggtcggtctgcaggccgtctccgaggggctggacgtggtcttcaaggaggccggcgcc
gagtggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccagctggccccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggcaggcagggcaagggcggc
cgtacgcacctggtctcgccgcaggtcgccgccgccaccgccgtgctcggccacctcgcc
tctccggccgacctgtccgacgcccgtacgcccgctggagtctga
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