Streptomyces dengpaensis: C4B68_29730
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Entry
C4B68_29730 CDS
T06611
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sdx
Streptomyces dengpaensis
Pathway
sdx00300
Lysine biosynthesis
sdx00550
Peptidoglycan biosynthesis
sdx01100
Metabolic pathways
sdx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sdx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C4B68_29730
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C4B68_29730
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C4B68_29730
Enzymes [BR:
sdx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C4B68_29730
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AVH59236
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Position
6455422..6456843
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AA seq
473 aa
AA seq
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MIALSLAEIAAVVGGQTYDIPDLSVQITGPVVRDSREVESGSLFVAFVGERVDGHDFAEA
VIEAGAVALLASRPVGVPAIVVADVRAALGALARHVVERLGATLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSLNNEIGLPLTALSATEETRFLVLEMGARGVGHIRYLTDLTPPKI
GLVLNVGTAHIGEFGGREHIAQAKGEIVEALPEDGTAILNADDPLVRAMASRTKARVLLF
GESDEADVRAENVRLTDNGQPAFSLRTPSGCSDVTMRLYGEHHVSNALAAAAVAHELGMS
ADEIAVALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGKASQAKG
GRTWAVLGEMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLERVAQALLDSGAEGEVAAR
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctctctcgccgagatcgcagcagtcgtcggcgggcagacctacgacata
ccggatctgtcggtacagatcaccggaccggtcgtccgggactcccgtgaggtggagtcc
ggcagcctcttcgtcgccttcgtgggcgagcgggtggacggccatgacttcgccgaggcg
gtgatcgaggcgggcgcggtcgccctcctggcgtcccgccccgtcggcgtgcccgcgatc
gtcgtcgcggacgtgcgggcagccctcggtgccctcgcccgccatgtcgtcgaacggctc
ggcgcgaccctcgtggccctcaccggctccgcgggcaagaccagcaccaaggacctcatc
gcgcaggtgctgcggcgcaaggcgccgaccgtcttcacgcccggttcgctcaacaacgag
atcggactgccgctcaccgcgctcagcgccaccgaggagaccaggttcctcgtgctggag
atgggcgcccgcggcgtcggccacatccgctacctcacggatctgacgcctccgaagatc
ggcctcgtcctcaacgtcggcaccgcccacatcggcgagttcggcggccgcgaacacatc
gcacaggcgaagggtgagatcgtcgaggccctcccggaggacggcaccgcgatcctcaac
gccgacgatcccctcgtacgcgccatggcgtcccgtacgaaggcacgcgtgctcctcttc
ggggagtccgacgaagcggacgtacgcgccgagaacgtccgtctcacggacaatggacag
cccgccttcagccttcgcacaccctccgggtgcagtgacgtgaccatgcgcctgtacggt
gagcatcacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcagacgagatcgccgtggcgctctccgaggcgggctccctctcccgctggcggatggag
gtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcgaaccccgag
tccatgcgagccgccctgcgcgcgctcgcggccatgggcaaagcctcacaggcgaagggg
ggccgtacgtgggcggtgctcggtgagatggccgagctcggtgacgaggcgctcgccgag
cacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgcggtcggg
ggcagggaagcgtcctggctccaactgggcgcatataacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggctgtcgacctgttgcgcagtgaactgcgccca
ggagacgtcgtactcgtgaaggcgtccaggtcggtcgggctcgaacgggtggcccaggcg
ctgctcgacagcggtgccgagggtgaggttgccgcccgatga
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