KEGG T00306: SDY

Shigella dysenteriae Sd197: SDY_0099

Entry

SDY_0099          CDS       T00306

Symbol

leuC

Name

(GenBank) 3-isopropylmalate isomerase subunit

K01703

3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]

Organism

sdy Shigella dysenteriae Sd197

Pathway

sdy00290

Valine, leucine and isoleucine biosynthesis

sdy00660

C5-Branched dibasic acid metabolism

sdy01100

Metabolic pathways

sdy01110

Biosynthesis of secondary metabolites

sdy01210

2-Oxocarboxylic acid metabolism

sdy01230

Biosynthesis of amino acids

Module

sdy_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Brite

KEGG Orthology (KO) [BR:sdy00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    SDY_0099 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SDY_0099 (leuC)
Enzymes [BR:sdy01000]
4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     SDY_0099 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     SDY_0099 (leuC)

SSDB

Motif

Pfam:

Aconitase

Other DBs

NCBI-ProteinID:

ABB60335

ShiBASE_China:

SDY0099

UniProt:

Q32K22

LinkDB

Position

complement(100049..101449)

AA seq 466 aa
MAKTLYEKLFDTHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERALAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK

NT seq 1401 nt +upstreamnt +downstreamnt
atggctaagacgttatacgaaaaattgttcgacactcacgtagtgtacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccggggaaaaccttcgccacg
atggatcacaacgtttcaactcagaccaaagacattaatgcctgcggtgaaatggcgcgt
atccagatgcaggagctgatcaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtgatggggccggaacagggcgtgaccttgccg
gggatgaccattgtctgcggcgactcgcacaccgccacccacggcgcgtttggcgcactg
gcctttggtatcggtacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgcgcaaagaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgttggcaattatcggtaaaactggcagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaatccgtgatttaagcatggaaggtcggatgaccctgtgc
aatatggcaatcgaaatgggcgcgaaagccggtctggttgcaccggacgaaaccaccttt
aactatgtcaaaggccgtttgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactctgcaa
gcagaagagatttcgccgcaggtcacctggggcaccaatccaggccaggtgatttccgtg
aacgacaatattcccgatccggcttcgtttgccgatccagttgaacgtgcgttggcagaa
aaagcgctggcctatatggggttgaaaccgggcattccactgacagaagtggctatcgac
aaagtgtttatcggctcctgcaccaactcgcgcattgaagatttacgcgcggcggctgaa
atcgccaaaggccggaaagtcgcgccaggcgtgcaggcactggtggttcccggctctggc
ccggtaaaagcccaggcggaagcggaaggtctggacaaaatctttattgaagccggtttt
gaatggcgcttgccaggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccg
ggcgaacgttgtgcctccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgccgcggctgtgaccggacatttcgcc
gacattcgcaacattaaataa

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