KEGG   Shigella dysenteriae Sd197: SDY_0281
Entry
SDY_0281          CDS       T00306                                 
Symbol
folD
Name
(GenBank) 5,10-methylene-tetrahydrofolate dehydrogenase
  KO
K01491  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
Organism
sdy  Shigella dysenteriae Sd197
Pathway
sdy00670  One carbon pool by folate
sdy00720  Other carbon fixation pathways
sdy01100  Metabolic pathways
sdy01120  Microbial metabolism in diverse environments
sdy01200  Carbon metabolism
sdy01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:sdy00001]
 09100 Metabolism
  09102 Energy metabolism
   00720 Other carbon fixation pathways
    SDY_0281 (folD)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SDY_0281 (folD)
Enzymes [BR:sdy01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     SDY_0281 (folD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     SDY_0281 (folD)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH PF1197-like_C
Other DBs
NCBI-ProteinID: ABB60500
ShiBASE_China: SDY0281
UniProt: Q32JK7
LinkDB
Position
complement(274853..275719)
AA seq 288 aa
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEE
VGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDV
DGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELL
LAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKV
VGDVVFEDAAKHASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
NT seq 867 nt   +upstreamnt  +downstreamnt
atggcagcaaagattattgacggtaaaacgattgcgcagcaggtgcgctctgaagttgct
caaaaagttcaggcgcgtattgcagccggactgcgggcaccaggactggccgttgtgctg
gtgggtagtaaccctgcatcgcaaatttatgtcgcaagcaaacgcaaggcttgtgaagaa
gtcgggttcgtctcccgctcttacgacctcccggaaaccaccagcgaagcggagctgctg
gagcttatcgatgcgctgaatgccgataacaccatcgatggcattctggttcaactgccg
ttaccggcgggtattgataacgtcaaagtactggaacgtatacacccggacaaagacgta
gacggtttccatccttataacgtcggtcgcctgtgccagcgcgcgccgcgtctgcgtccc
tgcaccccgcgcggtattgtcacgctgcttgagcgttacaacattgataccttcggcctc
aacgccgtggtgattggcgcatcgaatatcgttggccgcccgatgagcatggaactgttg
ctcgcaggttgcaccaccaccgtgactcaccgcttcactaaaaatctgcgtcatcacgta
gaaaatgccgatctgttgatcgttgccgttggtaagccaggctttattcccggtgactgg
ataaaagaaggcgcaattgtgattgatgtcggcatcaaccgcctggaaaatggcaaggtt
gtgggcgacgtcgtgtttgaagacgcggctaaacacgcctcatacattacgcctgttccc
ggcggcgttggcccgatgacggttgccacgctgattgaaaacacgctacaggcgtgcgtt
gaatatcatgatccacaggatgagtaa

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