KEGG   Shigella dysenteriae Sd197: SDY_2868
Entry
SDY_2868          CDS       T00306                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase 2, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
sdy  Shigella dysenteriae Sd197
Pathway
sdy00230  Purine metabolism
sdy00240  Pyrimidine metabolism
sdy01100  Metabolic pathways
sdy01232  Nucleotide metabolism
Module
sdy_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
sdy_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:sdy00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    SDY_2868 (nrdE)
   00240 Pyrimidine metabolism
    SDY_2868 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:sdy03400]
    SDY_2868 (nrdE)
Enzymes [BR:sdy01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     SDY_2868 (nrdE)
DNA repair and recombination proteins [BR:sdy03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    SDY_2868 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-ProteinID: ABB62905
ShiBASE_China: SDY2868
UniProt: Q32CQ0
LinkDB
Position
2652251..2654101
AA seq 616 aa
MDYHALNAMLNLYDSAGRIQFDKDRQAVDAFIATHVRPNSVTFSSQQQRLNWLVNEGYYD
ESVLNRYSRNFVITLFAHAHTSGFRFQTFLGAWKFYTSYTLKTFDGKRYLEDFADRVTMV
ALTLAQGDETLALQLTDEMLSGRFQPATPTFPNCGKQQRGELVSCFLLRIEDNMESIGRA
VNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLEDAFSYANQLGARQG
AGAVYLHAHHPDILRFLDTKRENADEKIRIKILSLGVVIPDITFHLAKENAQMALFSPYD
VERVYGKPFADVAISQHYDELVADERIRKKYLNARDFFQRLVEIQFESGYPYIMYEDTVN
RANPIAGRINMSNLCSEILQVNSASEYDENLDYTCTGHDISCNLGSLNIAHTMDSPDFAR
TVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDF
TNLYFYAITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELF
TRSGITLPTHEMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRK
EGKTGRVYYPAPFMTN
NT seq 1851 nt   +upstreamnt  +downstreamnt
atggattaccacgcgctgaatgcgatgcttaacctctacgatagcgcaggtcgcattcag
ttcgataaagaccgccaggccgttgacgcctttattgcgacgcatgtgcgtccgaacagt
gtgaccttcagtagccagcagcagcgcctgaactggctggtcaacgaaggttactatgat
gaaagcgttcttaatcgctactctcgcaactttgtcattacgctgtttgcccacgcacac
accagcggttttcgtttccagacattcctcggggcatggaagttttacaccagctatacg
ttgaagacattcgacggtaaacgttatctggaagattttgccgatcgagtaacgatggtg
gcgctgacgctggcacaaggcgatgagacgctggcgttgcaactgaccgatgaaatgctg
tcaggacgctttcagccagccacgccaacattccccaactgcggtaagcagcagcgcggc
gaactagtttcctgttttctgctgcgtattgaagacaatatggagtcgattggccgggcg
gtaaattccgcactacaactgtcgaaacgcggcggcggcgtggcatttttgctgtcgaat
ctgcgagaagcgggcgcgccaattaaacgtattgaaaatcaatcttctggcgtaattccg
gtgatgaaaatgctggaagacgcattttcctatgccaaccaactcggcgcgcgtcagggg
gctggtgcagtctatttacatgctcatcatcccgatattctgcgttttctcgacacgaaa
cgggaaaatgccgacgaaaaaatccgcattaaaatactgtcgcttggcgtggtgatcccg
gatatcactttccatctggcaaaagagaatgcgcagatggcgctgttttcgccttatgac
gtagagcgagtttatggcaagccgtttgccgatgtggccatcagccaacactatgacgaa
ctggttgccgatgaacgcattcgcaaaaaatacctcaacgcccgtgatttcttccagcga
ctggtagaaatccagtttgagtccggctatccgtacatcatgtatgaagacacggtaaac
cgtgctaaccctatcgccgggcgcataaatatgagtaatctctgctcagaaattttgcag
gttaacagcgcctcagagtatgacgagaatctcgactatacctgcacaggccatgatatt
tcctgcaatttaggttcgttgaatattgcgcacaccatggattcccccgattttgcccgc
acggtagagactgccgtgcgcggtttaacggcagtatcggatatgagtcatatccgcagc
gtgccgtccatcgaagccggaaatgccgcctcgcacgccatcggactggggcagatgaat
ttacacggctatctggcgcgagaaggcatcgcttatggttcgccggaagcactggatttc
accaatctctatttctatgccatcacctggcacgcactgcgtacctcgatgttgctggca
cgcgaacgcggtgaaaccttcgccgggttcaaacagtcacgctatgccagtggtgaatat
tttagccaatatctgcaagggaactggcagccgaaaacggcgaaagttggcgaactgttt
acccgtagcggtattacgttacctacccatgagatgtgggcgcagctgcgcgacgacgtg
atgcgctacggcatttacaaccagaatcttcaggcggtgccgccaaccggttctatctct
tatatcaaccatgctacgtcgagtattcatccgattgtggcgaaagtagagatacgcaaa
gagggcaaaacaggacgcgtttactaccctgccccgtttatgactaactaa

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