KEGG T00757: SeD

Salmonella enterica subsp. enterica serovar Dublin: SeD_A0122

Entry

SeD_A0122         CDS       T00757

Symbol

leuA

Name

(GenBank) 2-isopropylmalate synthase

K01649

2-isopropylmalate synthase [EC:2.3.3.13]

Organism

sed Salmonella enterica subsp. enterica serovar Dublin

Pathway

sed00290

Valine, leucine and isoleucine biosynthesis

sed00620

Pyruvate metabolism

sed01100

Metabolic pathways

sed01110

Biosynthesis of secondary metabolites

sed01210

2-Oxocarboxylic acid metabolism

sed01230

Biosynthesis of amino acids

Module

sed_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Brite

KEGG Orthology (KO) [BR:sed00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    SeD_A0122 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SeD_A0122 (leuA)
Enzymes [BR:sed01000]
2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     SeD_A0122 (leuA)

SSDB

Motif

Pfam:

HMGL-like LeuA_dimer HCS_D2 IPMS_D2 Trp_syntA

Other DBs

NCBI-ProteinID:

ACH76469

UniProt:

B5FI58

LinkDB

Position

complement(127783..129354)

AA seq 523 aa
MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIE
RAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKA
EAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV

NT seq 1572 nt +upstreamnt +downstreamnt
atgagccagcaagtcattatttttgatacgaccttacgcgacggcgaacaagcgttacag
gccagcctgagcgcgaaagagaagctgcagattgccctggcccttgagcgcatgggtgtt
gatgtcatggaagtgggcttcccggtctcttctccgggtgattttgaatccgtccaaacc
atcgcccgcaccattaaaaacagccgcgtttgcgccctggcgcgttgtgtagaaaaagac
attgacgtcgcggcacaggcgctgaaggtcgccgacgcgtttcgcatccatacttttatc
gccacctcgccaatgcacatcgccaccaaactgcgcagcacgctggatgaggtcatcgaa
cgcgcggtatacatggttaagcgggcgcgtaattacactgatgacgtagagttctcctgc
gaagatgctggccggacgcctgttgacgatctggcgcgcgtggtagaagccgctataaac
gccggcgcgagaaccattaatattcccgataccgtgggctataccatgccgtttgagttc
gcgggaatcatttccggcctgtatgaacgtgtccccaatatcgacaaagctatcatctcc
gttcatacccacgacgatttagggatagcagtaggcaactcgctggcggcagtacatgcg
ggcgcgcgtcaggttgaaggcgcgatgaacggtatcggagaacgtgccggtaactgcgca
ctggaagaagtgatcatggcgattaaagtgcgcaaagacatcatgaatgtacacaccaac
atcaatcaccacgaaatctggcgcaccagccagaccgtcagccagatctgtaacatgccg
atcccggccaacaaagcgattgtcggcagcggcgcttttgcccactcttccggcatccac
caggatggcgtcctcaagaaccgcgaaaactatgaaatcatgacgccagagtccatcggt
ctgaaccagatacagctgaacctgacctcccgctctggccgtgccgccgtgaaacatcgc
atggaagagatgggttacaaggacacagactacaacatggatcacctgtacgacgcgttc
ctgaagctggcggacaaaaaaggccaggtgttcgactatgacctggaagcgctggcgttt
attaataaacagcaagaagaaccagagcatttccgtctggattacttcagcgtgcagtcc
ggctccagcgatatcgccactgcttccgtgaagctggcctgtggtgaagagatcaaggcc
gaagcggcgaacggcaacggcccggtcgacgccatctatcaggcgattaaccgcatcact
ggctacgacgttgagttggttaaatacgacctgaacgccaaaggccagggcaaagacgcg
ctgggtcaggtcgatatcgtcgtgaaccatcatggtcgccgcttccacggcgtcgggctg
gcgacggatatcgtcgaatcctccgccaaagcgatggtgcacgtactgaacaatatctgg
cgcgccgccgaagttgaaaaagaattgcaacgcaaagctcaaaataaagagaacaacaag
gaaaccgtgtaa

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