Salmonella enterica subsp. enterica serovar Dublin: SeD_A0361
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Entry
SeD_A0361 CDS
T00757
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sed
Salmonella enterica subsp. enterica serovar Dublin
Pathway
sed00290
Valine, leucine and isoleucine biosynthesis
sed00660
C5-Branched dibasic acid metabolism
sed01100
Metabolic pathways
sed01110
Biosynthesis of secondary metabolites
sed01210
2-Oxocarboxylic acid metabolism
sed01230
Biosynthesis of amino acids
Module
sed_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sed00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SeD_A0361 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SeD_A0361 (leuC)
Enzymes [BR:
sed01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SeD_A0361 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SeD_A0361 (leuC)
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Gene cluster
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ACH74748
UniProt:
A0A6C6ZW97
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All DBs
Position
376163..377584
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AA seq
473 aa
AA seq
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MSAKTLYEKLVESHTIRELDNEGHVLLYIDRSILNEYTSPQAFSGLRERGRTVRHPDTFL
LNIDHVNPTRSQRDVLMTDPGGQLQVDYFRENAADFGITLFDVLDPRQGIEHVVAHEQGL
VMPGMVIAAGDSHTTTYGAFGALGFGIGTSEIEHLLATQTLVYRKLKTMRVSVQGELPFA
CSAKDIVLELLERIGADGATGYAIEFVGEAISALSVEGRMTLCNMAVEAGARGAIIAPDK
KVFDYIYGKPQMPVGELWQQALLEWSQLSSDADAVFDKTVAINCHDLEPKVTWGISPDQT
GSITGRVPFPEQETNPLKRLALEKALHYMGLTAGMLLKDIRISHAFIGSCTNGRIEDLRA
VAKVLEGRKIASHVRGIIVPGSTMVRRQAEEEGLAKIFIAAGFEWRQSGCSMCLAMNEDV
LSPGDRCASGTNRNFPGRQGAGARTHLMSPAMVAAAVVAGHLVDVRSLLQAGE
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgtctgctaaaacgctgtatgaaaaattagttgagtcacataccattcgtgaacttgat
aacgaaggacatgttttactttatattgatcgttcaatactgaatgaatataccagcccg
caggcatttagcgggttaagagaacgcggtcgcaccgttcggcaccccgacacgttttta
ttgaatattgaccatgttaatcccactcggtcgcaacgggatgtcttaatgaccgatccg
ggaggacagctacaggttgattactttcgggaaaatgccgctgactttggcatcacatta
tttgatgtgctggatccgcgtcaggggattgaacacgtggttgctcatgaacaagggcta
gtgatgcctggcatggtgatcgccgccggggatagtcacacgacaacctatggtgcattt
ggcgcgctgggctttggtatcgggacgtcggaaattgaacatctgctggccacgcagacg
ctggtttaccgcaagctcaaaaccatgcgcgtaagtgttcagggagagctacctttcgcc
tgttccgcaaaagatattgttcttgaattgcttgaacgtattggcgctgatggcgcgacc
ggatatgccattgaatttgtgggtgaggccatcagcgcgttgagcgttgaaggacgaatg
acgctctgcaacatggcggtagaagcgggggcgcgtggtgccattattgcgccggataaa
aaggtttttgactatatctacggtaaaccgcaaatgcctgtaggtgaactctggcagcag
gcattgctggaatggtcacagttgagcagcgatgctgatgcggtatttgataagacggtg
gcgatcaactgccatgatcttgagcctaaagtcacctggggaatcagtccggatcaaaca
ggttccatcaccggacgtgtccctttcccggaacaggaaaccaatccgcttaagcgcctg
gcgcttgagaaggcccttcattacatgggattaacggctggcatgttgctgaaagatatt
cgtatctctcacgcttttattggttcatgcacaaatggtcgcattgaggatttgcgtgcc
gttgcgaaggtgcttgaagggcgcaaaatcgccagccatgttcgcgggatcattgtgcct
ggttcaacaatggtaagacgccaggcggaagaagaaggactggcgaaaatctttattgct
gccggttttgaatggcggcagtcgggttgctcaatgtgccttgcgatgaatgaagatgtg
ttgtcgcccggcgatcgctgtgcatcaggtacgaaccgtaatttccctggacgacagggc
gctggagcaagaacgcatttgatgagcccggcgatggttgcggcggcggtggtagcgggg
catctggtcgatgttcggtcattacttcaggcaggggaataa
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