Salmonella enterica subsp. enterica serovar Newport SL254: SNSL254_A0125
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Entry
SNSL254_A0125 CDS
T00739
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
see
Salmonella enterica subsp. enterica serovar Newport SL254
Pathway
see00290
Valine, leucine and isoleucine biosynthesis
see00620
Pyruvate metabolism
see01100
Metabolic pathways
see01110
Biosynthesis of secondary metabolites
see01210
2-Oxocarboxylic acid metabolism
see01230
Biosynthesis of amino acids
Module
see_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
see00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SNSL254_A0125 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SNSL254_A0125 (leuA)
Enzymes [BR:
see01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SNSL254_A0125 (leuA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
ACF62937
UniProt:
B4SU36
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All DBs
Position
complement(133950..135521)
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIE
RAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNIDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKA
EAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattatttttgatacgaccttacgcgacggcgaacaagcgttacag
gccagcctgagcgcgaaagagaagctgcagattgccctggcccttgagcgcatgggtgtt
gatgtcatggaagtaggcttcccggtctcttctccgggtgattttgaatctgtccaaacc
atcgcccgcaccatcaaaaacagccgcgtttgcgccctggcgcgttgtgtagaaaaagac
atcgacgtcgcggcacaggcgctgaaggtcgccgacgcgtttcgcatccatacttttatc
gccacctcgccaatgcacatcgccaccaagctgcgcagcacgctggatgaggtcatcgaa
cgcgcggtatacatggttaagcgggcgcgtaattacactgatgacgtggaattctcctgc
gaagatgctggccggacgcctgttgacgatctggcgcgcgtggtggaagccgctataaac
gccggcgcgagaaccattaatattcccgataccgtgggctataccatgccgtttgagttc
gcgggaatcatttccggcctgtatgaacgtgtccccaatatcgacaaagctatcatctcc
gttcatacccacgacgatttagggatagcagtaggcaactcgctggcggcagtacatgcg
ggcgcgcgtcaggttgaaggcgcgatgaacggtatcggagaacgtgccggtaactgcgca
ctggaagaagtgatcatggcgattaaagtgcgcaaagacatcatgaacgtacacaccaac
atcaatcaccacgaaatctggcgcaccagccagaccgtcagccagatctgtaacatgccg
atcccggccaacaaagcgattgtcggcagcggcgctttcgcccactcttccggcatccac
caggatggcgtcctcaagaaccgcgaaaactatgaaatcatgacgccagagtccatcggt
ctgaaccagatacagctgaacctgacctcccgctctggccgtgccgccgtgaaacatcgc
atggaagagatgggttacaaggacacagactacaacatagaccacctgtacgacgcgttc
ctgaagctggcggacaaaaaaggccaggtgttcgactatgacctggaagcgctggcgttt
attaataaacagcaagaagaaccagagcatttccgtctggattacttcagcgtgcagtcc
ggctccagcgatatcgccaccgcttccgtgaagctggcctgtggtgaagagatcaaggcc
gaggcggcgaacggcaacggcccggtcgacgccatctatcaggcgattaaccgcatcact
ggctacgacgttgagttggttaaatacgacctgaacgccaaaggccagggcaaagacgcg
ctgggtcaggtcgatatcgtcgtaaaccatcatggtcgccgcttccacggcgtcgggctg
gcgacggatatcgtcgaatcctccgccaaagcgatggtgcacgtactgaacaatatctgg
cgcgccgccgaagttgaaaaagaattgcaacgcaaagctcaaaataaagagaacaacaag
gaaaccgtgtaa
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