Salmonella enterica subsp. enterica serovar Newport SL254: SNSL254_A0136
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Entry
SNSL254_A0136 CDS
T00739
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
see
Salmonella enterica subsp. enterica serovar Newport SL254
Pathway
see00300
Lysine biosynthesis
see00550
Peptidoglycan biosynthesis
see01100
Metabolic pathways
see01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
see00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SNSL254_A0136 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SNSL254_A0136 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SNSL254_A0136 (murF)
Enzymes [BR:
see01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SNSL254_A0136 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACF63049
UniProt:
A0A0H3BQE7
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Position
146745..148103
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AA seq
452 aa
AA seq
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MISVTLSKIADVLGAEHRGADLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKAN
GAGALLVSRPLDIDLPQVIVKDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWRFS
PNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATL
AAVKAGLAALKAVPGRLFPIQLSENQLVLDDAYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGAESEACHIQVGEAAKAAGIDRVLSTGKLSQAISHASGVGEHFADKAALIARLHAL
LQEQPMMTILVKGSRSAAMEDVVHALQEKGSC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacgctcagcaaaattgccgatgtccttggcgccgaacaccgcggggcg
gatctcacgctcgatacggtcattaccgacacacggaaagtgacgccgggatgcctgttc
gtggcgctgaaaggggaacgttttgatgcgcatgattttgccgataaagcaaaagcgaac
ggcgctggcgccctgctggtcagtcgtcctctggatatcgatcttccgcaggtgattgta
aaagacacgcgtcaggcatttggccaactggccgcctgggtacgtatgcaggtaccggcg
cgggtggtggcgttaaccggttcgtccggcaaaacctcggtcaaagagatgaccgccgcg
attcttagccagtgcggaaatactctgtataccgcaggcaattttaacaacgacatcggc
gtgccgataacgctgctgcgcttaaaccatgattatgactatgcggtaatcgagttaggc
gctaatcaccagggagaaatcgcctggaccgttagcctgacgcgcccggaagcggcgctg
gtcaataacctggcggcggcgcatctggaaggtttcggctcgctggccggcgtggcgaaa
gcgaaaggcgaaatctataccggtttgcctgagaacggtatcgcgattatgaatgccgat
aataatgactggctgaactggcaaagcattattggcgatcgtcaggtgtggcgcttttcg
ccgaatgcggcaaacagcgactttaccgctgcgaatatccacgtgacgtcacacggtacc
gaatttaccctgcaaacgccgatgggcagcattgatgtgctgctgccgttgccggggcgg
cacaatattgccaacgcgctggcggccgctgctttatcaatggcggtgggggcgacgctg
gcggcggttaaagcagggctggcggcgttaaaagccgtacccgggcgtctgttcccgatt
caactaagtgaaaaccaactggtactggatgacgcttataacgccaacgtcggttcgatg
accgccgcagtgcaggtcctttctgaaatgcccggctaccgtgtgctggtggtaggcgat
atggccgagttgggcgcagaaagcgaagcgtgccacatccaggttggcgaggccgcaaaa
gcggcgggtattgatcgcgtgttaagcaccggaaaactcagtcaggctatcagccacgcc
agcggcgtcggcgaacattttgccgataaagccgcgctcattgcgcgtttacacgctctg
cttcaggagcaaccaatgatgactattttagtgaaaggatcacgcagcgccgcgatggaa
gatgtggttcatgcgttacaggagaaaggttcatgttag
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