Salmonella enterica subsp. enterica serovar Heidelberg SL476: SeHA_C0421
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Entry
SeHA_C0421 CDS
T00738
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
seh
Salmonella enterica subsp. enterica serovar Heidelberg SL476
Pathway
seh00290
Valine, leucine and isoleucine biosynthesis
seh00660
C5-Branched dibasic acid metabolism
seh01100
Metabolic pathways
seh01110
Biosynthesis of secondary metabolites
seh01210
2-Oxocarboxylic acid metabolism
seh01230
Biosynthesis of amino acids
Module
seh_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
seh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SeHA_C0421 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SeHA_C0421 (leuC)
Enzymes [BR:
seh01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SeHA_C0421 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SeHA_C0421 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ACF66048
UniProt:
A0A6C6ZHH9
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Position
419900..421321
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AA seq
473 aa
AA seq
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MSAKTLYEKLVESHTIRELDNEGHVLLYIDRSILNEYTSPQAFSGLRERGRTVRHPDTFL
LNIDHVNPTRSQRDVLMTDPGGQLQVDYFRENAADFGITLFDVLDPRQGIEHVVAHEQGL
VMPGMVIAAGDSHTTTYGAFGALGFGIGTSEIEHLLATQTLVYRKLKTMRVSVQGELPFA
CSAKDIVLELLERIGADGATGYAIEFVGEAISALSVEGRMTLCNMAVEAGARGAIIAPDK
KVFDYIYGKPQMPVGELWQQALLEWSQLSSDADAVFDKTVAINCHDLEPKVTWGISPDQT
GSITGRVPFPEQETNPLKRLALEKALHYMGLTAGMLLKDIRISHAFIGSCTNGRIEDLRA
VAKVLEGRKIASHVRGIIVPGSTMVRRQAEEEGLAKIFIAAGFEWRQSGCSMCLAMNEDV
LSPGDRCASGTNRNFPGRQGAGARTHLMSPAMVAAAAVAGHLVDVRSLLQAGE
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
atgtctgctaaaacgctgtatgaaaaattagttgagtcacataccattcgtgaacttgat
aacgaaggacatgttttactttatattgatcgttcaatactgaatgaatataccagcccg
caggcatttagcgggttaagagaacgcggtcgcaccgttcggcaccccgacacgttttta
ttgaatattgaccatgttaatcccacgcggtcgcaacgggatgtcttaatgaccgatccg
ggaggacagctacaggttgattactttcgggaaaatgccgctgactttggcatcacatta
tttgatgtgctggatccgcgtcaggggattgaacacgtggttgctcatgaacaagggcta
gtgatgcctggcatggtgatcgccgccggggatagtcacacgacaacctacggtgcattt
ggcgcgctgggctttggtatcgggacgtcggaaattgaacatctgctggccacgcagacg
ttggtttaccgcaagctcaaaaccatgcgcgtaagtgttcagggagagctacctttcgcc
tgttccgcaaaagatattgttcttgaattgcttgaacgtattggcgctgatggcgcgacg
ggatatgccattgaatttgtgggtgaggccatcagcgcgttgagcgttgaaggacgaatg
acgctctgcaacatggcggtagaagcgggggcgcgtggtgctattattgcgccggataaa
aaggtttttgactatatctacggtaaaccgcaaatgcctgtaggtgaactctggcagcag
gcattgctggaatggtcacagttgagcagcgatgctgatgcggtatttgataagacggtg
gcgatcaactgccatgatcttgagcctaaagtcacctggggaatcagtccggatcaaaca
ggttccatcaccggacgtgtccctttcccggaacaggaaaccaatccgcttaagcgcctg
gcgcttgagaaggcccttcattacatgggattaacggctggcatgttgctgaaagatatt
cgtatctctcacgcttttattggttcatgcacaaatggtcgcattgaggatttgcgtgcc
gttgcgaaggtgcttgaagggcgcaaaatcgccagccatgttcgcgggatcattgtgcct
ggctcaacaatggtaagacgccaggcggaagaagaaggactggcgaaaatctttattgct
gccggttttgaatggcggcagtcgggttgctcaatgtgccttgcgatgaatgaagatgtg
ttgtcgcccggcgatcgctgtgcatcaggtacgaaccgtaatttccctggacgacagggc
gctggagcaagaacgcatttgatgagcccggcgatggttgcggcggcggcggtagcgggg
catctggtcgatgttcggtcattacttcaggcaggggaataa
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