Salmonella enterica subsp. enterica serovar Paratyphi C: SPC_0133
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Entry
SPC_0133 CDS
T00862
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diami nopimelate--D-alan alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sei
Salmonella enterica subsp. enterica serovar Paratyphi C
Pathway
sei00300
Lysine biosynthesis
sei00550
Peptidoglycan biosynthesis
sei01100
Metabolic pathways
sei01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sei00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SPC_0133 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SPC_0133 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SPC_0133 (murF)
Enzymes [BR:
sei01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SPC_0133 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACN44324
UniProt:
C0Q5I2
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Position
139300..140658
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AA seq
452 aa
AA seq
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MISVTLSKIADVLGAEHRGADLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKAN
GAGALLVSRPLDIDLPQVIVKDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRQVWRFS
PNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATL
TAIKAGLAALKAVPGRLFPIQLSENQLVLDDAYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGAESEACHIQVGEAAKAAGIDRVLSTGKLSQAISHASGVGEHFADKAALIARLHAL
LQEQPMMTILVKGSRSAAMEDVVHALQEKGSC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacgctcagcaaaattgccgatgtccttggcgctgaacaccgcggggcg
gatctcacgctcgatacggtcattaccgacacacggaaagtgacgccgggatgcctgttc
gtggcgctgaaaggggaacgctttgatgcgcatgattttgccgataaagcaaaagcgaac
ggcgctggcgccctgctggtcagtcgtcctctggatatcgatctcccgcaggtgattgta
aaagacacgcgtcaggcatttggccaactggccgcctgggtacgtatgcaggtaccggcg
cgggtggtggcgttaaccggttcgtccggcaaaacctcggtcaaagagatgaccgccgcg
attctgagccagtgcggaaatactctgtataccgcaggcaattttaacaacgacatcggc
gtgccgataacgctgctgcgcttaaaccatgattatgactatgcggtaatcgagttaggc
gctaatcaccagggagaaatcgcctggaccgttagcctgacgcgcccggaagcggcgctg
gtcaataacctggcggcggcgcatctggaaggtttcggctcgctggccggcgtggcgaaa
gcgaaaggcgaaatctataccggtttgcctgagaacggtatcgcgattatgaatgccgat
aataatgactggctgaactggcaaagcattattggcgatcgtcaggtgtggcgcttttcg
ccgaatgcggcaaacagcgactttaccgctgcgaatattcacgtgacgtcacacggtact
gaatttaccctgcaaacgccgatgggcagcattgatgtgctgctgccgttgccggggcgg
cacaatattgccaacgcgctggcggccgctgctttatcaatggcggtgggggcgacgctg
acggcgattaaagcagggctggcggcgttaaaagccgtacccgggcgtctgttcccgatt
cagctaagtgaaaaccaactggtactggatgacgcttataacgccaacgtcggttcgatg
accgccgcagtgcaggtcctttctgaaatgcccggctaccgtgtgctggtggtaggcgat
atggccgagctgggcgcagaaagcgaagcgtgccacatccaggttggcgaggccgcaaaa
gcggcgggtattgatcgcgtgttaagcaccggaaaactcagtcaggctatcagccacgcc
agcggcgtcggcgaacattttgccgataaagccgcgctcattgcgcgtttacacgctctg
cttcaggagcaaccaatgatgactattttagtgaaaggatcacgcagcgccgcgatggaa
gatgtggttcatgcgttacaggagaaaggttcatgttag
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