Saccharopolyspora erythraea: SACE_6144
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Entry
SACE_6144 CDS
T00492
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sen
Saccharopolyspora erythraea
Pathway
sen00290
Valine, leucine and isoleucine biosynthesis
sen00660
C5-Branched dibasic acid metabolism
sen01100
Metabolic pathways
sen01110
Biosynthesis of secondary metabolites
sen01210
2-Oxocarboxylic acid metabolism
sen01230
Biosynthesis of amino acids
Module
sen_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sen00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SACE_6144 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SACE_6144 (leuC)
Enzymes [BR:
sen01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SACE_6144 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SACE_6144 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
CAM05317
Kitasato:
SACE_6144
Cambridge:
SACE_6144
UniProt:
A4FMP2
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Position
complement(6889069..6890472)
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AA seq
467 aa
AA seq
DB search
MGKTLAEKVWEAHIVRRGEGYEPDLLYIDLHLVHEVTSPQAFEGLRLAGRQVRRPDLTLA
TEDHNVPTTGIDLPIADPVSRTQVDTLRRNCEEFGIRLHPMGDAEQGIVHVVGPQLGLTQ
PGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPLRPFKTMAINIEGTLRPGVT
SKDVILAVIAKIGTGGGQGYVLEYRGSAVEKMSMEARMTMCNMSIEAGARAGMIAPDETT
FAYLQGRPHAPEGTEWDAAVEYWKTLRTDEDAEFDAEVTLDADELTPFVTWGTNPGQGLP
LGARIPDPAAIADESERFATEKALDYMGLEAGTPLREVAVDTVFLGSCTNGRIEDLRAAA
DVLKGRKVASEVRMLVVPGSMRVRKQAEAEGLNEVFTAAGAEWRSAGCSMCLGMNPDQLT
PGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDLD
NT seq
1404 nt
NT seq
+upstream
nt +downstream
nt
atgggcaagacgctcgcggagaaggtctgggaagcgcacatcgtgcgccgcggcgagggc
tacgagcccgacctgctctacatcgacctccacctcgttcacgaggtcaccagcccgcag
gccttcgaggggctgcgcctggcggggcggcaggtgcgccgtcccgacctgacgctggcc
accgaggaccacaacgtgcccaccacgggcatcgacctgccgatcgcggacccggtttcg
cggacccaggtcgacaccctgcggcgcaactgcgaggagttcggcatccgcctgcacccg
atgggcgacgccgagcagggcatcgtgcacgtggtggggccccagctcggcctcacccag
cccggcacgaccgtcgtctgcggcgacagccacacctcgacccacggcgcgttcggcgcg
ctggccttcggcatcggcacctccgaggtcgagcacgtgctggcgacgcagacgcttccg
ttgcgtcccttcaagaccatggccatcaacatcgagggcacgctgcgcccgggggtcacg
agcaaggacgtgatcctggccgtcatcgccaagatcggcaccggcggcgggcagggctac
gtgctggagtaccggggcagcgccgtcgagaagatgtcgatggaagcccgcatgacgatg
tgcaacatgtcgatcgaggcgggtgcgcgggccggcatgatcgcgcccgacgagaccact
ttcgcctacctgcagggccgtccgcacgccccggagggcacggagtgggacgccgcggtc
gagtactggaagacgcttcgcaccgacgaggacgccgagttcgacgccgaggtgaccctc
gacgccgacgagctgaccccgttcgtcacgtggggcaccaaccccggtcagggcctgccg
ctgggcgctcggatcccggaccccgccgccatcgccgacgagagcgagcgcttcgcgacc
gagaaggcgttggactacatgggcctggaagcgggcactccgctgcgcgaggtggccgtg
gacacggtgttcctcggttcctgcaccaacggccggatcgaagatcttcgggccgcagcg
gacgttctgaagggccgcaaggtggcttcggaggtgcgcatgctggtcgtcccgggctcg
atgagggtccgcaagcaggccgaggccgaggggctcaacgaggttttcaccgccgccggg
gcggaatggcgttcggccggttgttcgatgtgcctgggcatgaaccccgaccagctcacc
cccggggagcgcagcgcgtcgacctccaaccgtaacttcgagggcaggcaaggaaagggc
ggccgcacccacctggtctcgccgctggtggccgccgcgaccgcggtgcgcggcaccctc
tcctcgcccgaagacctcgactga
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