Salmonella enterica subsp. enterica serovar Typhimurium DT104: DT104_21321
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Entry
DT104_21321 CDS
T02874
Symbol
hisB
Name
(GenBank) bifunctional histidine biosynthesis protein (imidazoleglycerol-phosphate dehydratase; histidinol phosphatase)
KO
K01089
imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:
4.2.1.19
3.1.3.15
]
Organism
send
Salmonella enterica subsp. enterica serovar Typhimurium DT104
Pathway
send00340
Histidine metabolism
send01100
Metabolic pathways
send01110
Biosynthesis of secondary metabolites
send01230
Biosynthesis of amino acids
Module
send_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
send00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
DT104_21321 (hisB)
Enzymes [BR:
send01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.15 histidinol-phosphatase
DT104_21321 (hisB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.19 imidazoleglycerol-phosphate dehydratase
DT104_21321 (hisB)
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Motif
Pfam:
IGPD
Hydrolase_like
HAD_2
PNK3P
HAD
Hydrolase
PGP_phosphatase
Motif
Other DBs
NCBI-ProteinID:
CCW74836
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Position
2219937..2221004
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AA seq
355 aa
AA seq
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MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPEVIPVLLKLQKAGFKLVMITNQDGLG
TQSFPQADFDGPHNLMMQIFTSQGVCFDEVLICPHLPADDCDCRKPKVKLVERYLAEQAM
DSANSYVIGDRATDIQLADNMGITGLRYHRETLNWTMIGEQLTKRDRYAHVVRNTKETQI
DVSVWLDREGNSKINTGVGFFDHMLDQIATHGGFRMEITVKGDLYIDDHHTVEDTGLALG
EALKLALGDKRGICRFGFVLPMDECLARCALDISGRPHLEYKAEFTYQRVGDLSTEMIEH
FFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFGRTLRQAIRVEGDTLPSSKGVL
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
atgagtcagaagtatcttttcatcgaccgggacggaaccttaatttccgaaccgccgagc
gattttcaggtagaccgctttgataaactggcctttgagccagaggtgattcccgtattg
ctgaagctgcaaaaagccggttttaagctggtgatgatcactaaccaggatggacttggc
acgcaaagcttcccgcaggcggacttcgacggaccgcacaacctgatgatgcagattttc
acctctcagggcgtatgctttgatgaggtgctgatctgccctcacctgcccgcagacgac
tgcgactgccgcaagcccaaagtgaagctggtggagcgttatcttgcggaacaagcgatg
gatagcgccaacagctatgtgattggcgatcgtgcgaccgatatccagctcgctgataac
atgggcattactggtttacgctatcaccgtgaaacgctgaactggacgatgattggcgaa
cagctaacgaaacgcgatcgttatgcgcatgtggtccgcaacaccaaagaaacacagatt
gatgtcagcgtctggctggatcgcgaaggcaacagcaagattaataccggcgtcggcttc
tttgaccatatgctcgatcaaatcgccacccacggcggctttcgcatggagattaccgtt
aagggcgatctctatatcgacgatcaccacacggtagaagataccggactggcgctcggt
gaggcattaaaactggcactcggcgacaagcgcggtatctgccgttttggctttgtacta
ccgatggatgaatgtctggcgcgctgcgcgctggatatttccggtcgtccgcatctggaa
tataaagctgaatttacctaccagcgtgtgggcgatttgagcacagagatgattgaacac
tttttccgctcactctcttacacgatgggcgtcactctgcatctcaagactaaaggtaag
aacgatcaccaccgtgtcgaaagtttgtttaaagcctttggtcggacgctacgccaggct
attcgcgtggagggcgatacattaccgtcctcgaaaggagtgctgtga
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