Salmonella enterica subsp. enterica serovar Thompson: IA1_00575
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Entry
IA1_00575 CDS
T02868
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sene
Salmonella enterica subsp. enterica serovar Thompson
Pathway
sene00290
Valine, leucine and isoleucine biosynthesis
sene00620
Pyruvate metabolism
sene01100
Metabolic pathways
sene01110
Biosynthesis of secondary metabolites
sene01210
2-Oxocarboxylic acid metabolism
sene01230
Biosynthesis of amino acids
Module
sene_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sene00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
IA1_00575
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
IA1_00575
Enzymes [BR:
sene01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
IA1_00575
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
AGX09435
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Position
complement(132275..133846)
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIE
RAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKA
EAANGNGPVDAIYQAINRLTGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattatttttgatacgaccttacgcgacggcgaacaagcgttacag
gccagcctgagcgcgaaagagaagctgcagattgccctggcccttgagcgcatgggtgtt
gatgtcatggaagtaggcttcccggtctcttctccgggtgattttgaatctgtccaaacc
atcgcccgcaccatcaaaaacagccgcgtttgcgccctggcgcgttgtgtagaaaaagac
atcgacgtcgcggcacaggcgctgaaggtcgccgacgcgtttcgcatccatacttttatc
gccacctcgccaatgcacatcgccaccaagctgcgcagcacgctggatgaggtcatcgaa
cgcgcggtatacatggttaagcgggcgcgtaattacactgatgacgtggagttctcctgc
gaagatgctggccggacgcctgttgacgatctggcgcgcgtggtggaagccgctataaac
gccggcgcgagaaccattaatattcccgataccgtgggctataccatgccgtttgagttc
gcgggaatcatttccggcctgtatgaacgtgtccccaatatcgacaaagccatcatctcc
gttcatacccacgacgatttagggatagcggtaggcaactcgctggcggcagtacatgcg
ggcgctcgtcaggttgaaggcgcgatgaacggtatcggagaacgtgccggtaactgcgca
ctggaagaagtgatcatggcgattaaagtgcgcaaagacatcatgaacgtacacaccaac
atcaatcaccacgaaatctggcgcaccagccagaccgtcagccagatctgtaacatgccg
atcccggccaacaaagcgattgtcggcagcggcgctttcgcccactcttccggcatccac
caggatggcgtcctcaagaaccgcgaaaactatgaaatcatgacgccagagtccatcggt
ctgaaccagatacagctgaacctgacctcccgctctggccgtgccgccgtgaaacatcgc
atggaagagatgggttacaaggacacagactacaacatggaccacctgtacgacgcgttc
ctgaagctggcggacaaaaaaggccaggtgttcgactatgacctggaagcgctggcgttt
attaataaacagcaagaagaaccagagcatttccgtctggattacttcagcgtgcagtcc
ggctccagcgatatcgccaccgcttccgtgaagctggcctgtggtgaagagatcaaggcc
gaggcggcgaacggcaacggcccggtcgacgccatctatcaggcgattaaccgcctcacc
ggttacgacgttgagttggttaaatacgacctgaacgccaaaggccagggcaaagacgcg
ctgggtcaggtcgatatcgtcgtaaaccatcatggtcgccgcttccacggcgtcgggctg
gcgacggatatcgtcgaatcctccgccaaagcgatggtgcacgtactgaacaatatctgg
cgcgccgccgaagttgaaaaagaattgcaacgcaaagctcaaaataaagagaacaacaag
gaaaccgtgtaa
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