Streptomyces endophytica: OJ254_09275
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Entry
OJ254_09275 CDS
T09208
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
seng
Streptomyces endophytica
Pathway
seng00280
Valine, leucine and isoleucine degradation
seng00640
Propanoate metabolism
seng00785
Lipoic acid metabolism
seng01100
Metabolic pathways
seng01110
Biosynthesis of secondary metabolites
seng01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
seng00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
OJ254_09275 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
OJ254_09275 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
OJ254_09275 (pdhA)
Enzymes [BR:
seng01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
OJ254_09275 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
UZJ30507
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Position
2042934..2044151
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AA seq
405 aa
AA seq
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MTVEGTAQRKNTRGSSKRTTAKKATPAKKASPAKARTNGRPDEAEQDQLVQLLTPEGKRV
EHPDYAIDLSPEELRGLYRDMVLTRKFDAEATTLQRQGELGLWASLLGQEAAQIGSGRAL
RDDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNHGGWDPNSNNFHLYTIVIGSQTLHAT
GYAMGVQKDGADSAVIAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEK
QTRVPLYQRARGYGFPGVRVDGNDVLACLAVTKAALERARTGQGPMLIEAFTYRMGAHTT
SDDPTRYRGDEERVAWEAKDPILRLRTYLEAEGLVDEAYLATIDEESEALGVRVREAVRA
MPDPDHMAIFENVYADGHALVDEERAQFAAYQASFVDADVLAEGN
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggaaggcactgcgcagcggaaaaacacccgcggcagcagcaagcgcaccacc
gccaagaaggcgacgcctgccaagaaggcgtcgccggccaaggcccgtaccaacggccgg
cccgacgaggcggagcaggatcagctcgtacaactgctgaccccggaagggaagcgggtc
gagcacccggactacgccatcgacctttcccccgaagaactgcgcggcctctaccgcgac
atggtgctgacgcggaagttcgacgccgaggcgaccaccctccagcgccagggcgagctg
ggcctgtgggcctcgctgctgggccaggaggccgctcagatcggctccggacgcgcgctg
cgcgacgacgactacgtcttcccgacgtaccgcgagcacggtgtggcgtggtgccgcggg
gtcgacccgacgaacctgctgggcatgttccgcggtgtcaatcacggcggctgggacccg
aacagcaacaacttccacctctacaccatcgtgatcggttcgcagacgctgcacgcgacc
ggttatgcgatgggtgtccagaaggacggcgcggattccgcggtcatcgcgtatttcggt
gacggtgcctccagccagggcgatgtcgcggaatccttcacgttctccgcggtgtacaac
gcccccgtcgtgttcttctgccagaacaatcagtgggccatttccgaacccaccgagaag
cagacccgggtgccgctctaccagcgcgcccgcggctacggattccccggcgtacgggtc
gacggcaacgacgtgctggcctgtctcgcggtgaccaaggcggcgctggagcgggcgcgc
accggccagggcccgatgctgatcgaggcgttcacgtaccggatgggcgcgcacaccacc
tccgacgacccgacgcgctaccgcggggacgaggagcgggtggcctgggaggccaaggac
ccgatcctgcggctgcggacgtacctggaggccgagggcctggtcgacgaggcgtacctc
gccaccatcgacgaggagagcgaggccctgggcgtgcgggtccgcgaggccgtccgtgcc
atgcccgacccggaccacatggcgatcttcgagaatgtctatgccgacgggcacgcgctc
gtcgatgaggagcgcgcgcagttcgccgcgtaccaggcgtcgttcgtcgatgccgatgtc
ctggcggaggggaactga
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