Salmonella enterica subsp. enterica serovar Typhimurium 138736: CY43_00560
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Entry
CY43_00560 CDS
T03493
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
seni
Salmonella enterica subsp. enterica serovar Typhimurium 138736
Pathway
seni00290
Valine, leucine and isoleucine biosynthesis
seni00620
Pyruvate metabolism
seni01100
Metabolic pathways
seni01110
Biosynthesis of secondary metabolites
seni01210
2-Oxocarboxylic acid metabolism
seni01230
Biosynthesis of amino acids
Module
seni_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
seni00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CY43_00560
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CY43_00560
Enzymes [BR:
seni01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CY43_00560
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
AHX75922
UniProt:
A0A0D6HK59
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All DBs
Position
complement(132167..133738)
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIE
RAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKA
EAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattatttttgatacgaccttacgcgacggcgaacaagcgttacag
gccagcctgagcgcgaaagagaagctgcagattgccctggcccttgagcgcatgggtgtt
gatgtcatggaagtaggcttcccggtctcttctccgggtgattttgaatccgtccaaacc
atcgcccgcaccattaaaaacagccgcgtttgcgccctggcgcgttgtgtagaaaaagac
atcgacgtcgcggcacaggcgctgaaggtcgccgacgcgtttcgcatccatacttttatc
gccacctcgccaatgcacatcgccaccaagctgcgcagcacgctggatgaggttatcgaa
cgcgcggtatacatggttaagcgggcgcgtaattacactgatgacgtagagttctcctgc
gaagatgctggccggacgcctgttgacgatctggcgcgcgtggtggaagccgctataaac
gccggcgcgagaaccattaatattcccgataccgtgggctataccatgccgtttgagttt
gcgggaatcatttccggcctgtatgaacgtgtccccaatatcgacaaagctatcatctcc
gttcatacccacgacgatttagggatagcagtaggcaactcgctggcggcagtacatgcg
ggcgcgcgtcaggttgaaggcgcgatgaacggtatcggagaacgtgccggtaactgcgca
ctggaagaagtgatcatggcgattaaagtgcgcaaagacatcatgaacgtacacaccaac
atcaatcaccacgaaatctggcgcaccagccagaccgtcagccagatctgtaacatgccg
atcccagccaacaaagcgattgtcggcagcggcgctttcgcccactcttccggcatccac
caggatggcgtcctcaagaaccgcgaaaactatgaaatcatgacgccagagtccatcggt
ctgaaccagatacagctgaacctgacctcccgctctggccgtgccgccgtgaaacatcgc
atggaagagatgggttacaaggacacagactacaacatggaccacctgtacgacgcgttc
ctgaagctggcggacaaaaaaggccaggtgttcgactatgacctggaagcgctggcgttt
attaataaacagcaagaagaaccagagcatttccgtctggattacttcagcgtgcagtcc
ggctccagcgatatcgccaccgcttccgtgaagctggcctgtggtgaagagatcaaggcc
gaagcggcgaacggcaacggtccggtcgacgccatctatcaggcgattaaccgcatcact
ggctacgacgttgagttggttaaatacgacctgaacgccaaaggccagggcaaagacgcg
ctgggtcaggtcgatatcgtcgtgaaccatcatggtcgccgcttccacggcgtcgggctg
gcgacggatatcgtcgaatcctccgccaaagcgatggtgcacgtactgaacaatatctgg
cgcgccgccgaagttgaaaaagaattgcaacgcaaagctcaaaataaagagaacaacaag
gaaaccgtgtaa
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