Salmonella enterica subsp. enterica serovar Typhimurium 138736: CY43_00615
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Entry
CY43_00615 CDS
T03493
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
seni
Salmonella enterica subsp. enterica serovar Typhimurium 138736
Pathway
seni00300
Lysine biosynthesis
seni00550
Peptidoglycan biosynthesis
seni01100
Metabolic pathways
seni01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
seni00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CY43_00615 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CY43_00615 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CY43_00615 (murF)
Enzymes [BR:
seni01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CY43_00615 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AHX75932
UniProt:
A0A0D6HHY7
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Position
144963..146321
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AA seq
452 aa
AA seq
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MISVTLSKIADVLGAEHRGADLTLDTVITDTRKVTPGCLFVALKGERFDAHDFADKAKAN
GAGALLVSRPLDIDLPQVIVKDTRQAFGQLAAWVRMQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNFNNDIGVPITLLRLNHDYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMNADNNDWLNWQSIIGDRLVWRFS
PNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLPLPGRHNIANALAAAALSMAVGATL
TAIKAGLAALKAVPGRLFPIQLSENQLVLDDAYNANVGSMTAAVQVLSEMPGYRVLVVGD
MAELGAESEACHLQVGEAAKAAGIDRVLSTGKLSQAISHASGVGEHFADKAALIARLHAL
LQEQPMMTILVKGSRSAAMEDVVHALQEKGSC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacgctcagcaaaattgccgatgtccttggcgccgaacaccgcggggcg
gatctcacgctcgatacggtcattaccgacacacggaaagtgacgccgggatgcctgttc
gtggcgctgaaaggggaacgctttgatgcgcatgattttgctgataaagcaaaagcgaac
ggcgctggcgccctgctggtcagtcgtcctctggatatcgatctcccgcaggtgattgta
aaagacacgcgtcaggcatttggccaactggccgcctgggtacgtatgcaggtaccggcg
cgggtggtggcgttaaccggttcgtccggcaaaacctcggtcaaagagatgaccgccgcg
attcttagccagtgcggaaatactctgtataccgcaggcaattttaacaacgacatcggc
gtgccgataacgctgctgcgcttaaaccatgattatgactatgcggtaatcgagttaggc
gctaatcaccagggagaaatcgcctggaccgttagcctgacgcgcccggaagcggcgctg
gtcaataacctggcggcggcgcatctggaaggcttcggctcgttggccggcgtggcgaaa
gcgaaaggcgaaatctataccggtttgcctgagaacggtatcgcgattatgaatgccgat
aataatgactggctgaactggcaaagcattattggcgatcgtctggtgtggcgcttttcg
ccgaatgcggcaaacagcgactttaccgctgcgaatatccacgtgacgtcacacggtacc
gaatttaccctgcaaacgccgatgggcagcattgatgtgctgctgccgttgccggggcgg
cacaatattgccaacgcgctggcggccgctgctttatcaatggcggtgggggctacgctg
acggcgattaaagcagggctggcggcgttaaaagccgtacccgggcgtctgttcccgatt
cagctaagtgaaaaccaactggtactggatgacgcttataacgccaacgttggttcgatg
accgccgcagtgcaggtcctttctgaaatgcccggctaccgcgtgctggtggtaggcgat
atggccgagctgggcgcagaaagcgaagcgtgccacctccaggttggtgaggccgcaaaa
gcggcgggtattgatcgcgtgttaagcaccggaaaactcagtcaggctatcagccacgcc
agcggcgtcggcgaacattttgccgataaagccgcgctcattgcgcgtttacacgctctg
cttcaggagcaaccaatgatgactattttagtgaaaggatcacgcagcgccgcgatggaa
gatgtggttcatgcgttacaggagaaaggttcatgttag
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