Salmonella enterica subsp. enterica serovar Enteritidis EC20090531: AU40_25160
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Entry
AU40_25160 CDS
T03761
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
senq
Salmonella enterica subsp. enterica serovar Enteritidis EC20090531
Pathway
senq00260
Glycine, serine and threonine metabolism
senq00261
Monobactam biosynthesis
senq00270
Cysteine and methionine metabolism
senq00300
Lysine biosynthesis
senq01100
Metabolic pathways
senq01110
Biosynthesis of secondary metabolites
senq01120
Microbial metabolism in diverse environments
senq01230
Biosynthesis of amino acids
Module
senq_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
senq_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
senq_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
senq00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AU40_25160 (thrA)
00270 Cysteine and methionine metabolism
AU40_25160 (thrA)
00300 Lysine biosynthesis
AU40_25160 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AU40_25160 (thrA)
Enzymes [BR:
senq01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AU40_25160 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AU40_25160 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AHR21893
LinkDB
All DBs
Position
101..2563
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFSDLLAGLASAQPGFPLARLKMVVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKMSIAIMAGLLEARGHRVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASSD
DDNLPVKGISNLNNMAMFSVSGPGMKGMIGMAARVFAAMSRAGISVVLITQSSSEYSISF
CVPQSDCARARRAMQDEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQTWLKNKHIDLRVCGVANSKALLTNVHGLNLDNWQAELAQANAPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRFAAAQSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQKFSGILSGSLSFIFGKLEEGMSLSQATALA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIVIEPVLPDEFDASGDVTAFMA
HLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatattctggaaagcaatgccaggcaagggcaggtagcgaccgtactttccgccccc
gcgaaaattaccaaccatctggtggcgatgattgaaaaaactatcggcggccaggatgct
ttgccgaatatcagcgatgccgaacgtattttttctgacctgctcgcaggacttgccagc
gcgcagccgggattcccgcttgcacggttgaaaatggttgtcgaacaagaattcgctcag
atcaaacatgttttgcatggtatcagcctgctgggtcagtgcccggatagcatcaacgcc
gcgctgatttgccgtggcgaaaaaatgtcgatcgcgattatggcgggacttctggaggcg
cgtgggcatcgcgtcacggtgatcgatccggtagaaaaactgttggcggtgggccattac
cttgaatctaccgtcgatatcgcggaatcgactcgccgtatcgccgccagccagatcccg
gccgatcacatgatcctgatggcgggctttaccgccggtaatgaaaagggtgaactggtg
gtgctgggccgtaatggttccgactattccgccgccgtgctggccgcctgtttacgcgct
gactgctgtgaaatctggactgacgtcgatggcgtgtatacctgtgacccgcgccaggtg
ccggacgccaggctgctgaaatcgatgtcctaccaggaagcgatggaactctcttacttc
ggcgccaaagttcttcaccctcgcaccattacgcccatcgcccagttccagatcccctgt
ctgattaaaaataccggtaatccgcaggcgccaggaacgctgatcggcgcgtccagcgac
gatgataacctgccggttaaagggatctctaaccttaacaacatggcgatgtttagcgtc
tccggcccgggaatgaaagggatgattgggatggcggcgcgtgttttcgccgccatgtct
cgcgccgggatctcggtggtgctcattacccagtcctcctctgagtacagcatcagcttc
tgtgtgccgcagagtgactgcgcgcgtgcccgccgtgcgatgcaggatgagttctatctg
gagctgaaagaggggctgctggagccgctggcggttacggagcggttggcgattatctct
gttgtcggcgacggtatgcgcacgctacgcggcatttcagcgaaattcttcgccgcgctg
gcgcgggctaatatcaatatcgtggcgatcgctcagggatcttctgagcgttccatttct
gtggtggtgaataacgacgatgccaccaccggcgtgcgggtaacgcaccagatgctgttc
aataccgatcaggtgattgaagtatttgtcattggcgtcggcggcgtcggcggcgcgcta
ctggaacagcttaaacgtcagcaaacctggttgaagaacaagcacatcgatctacgcgtg
tgcggcgtggcgaactcaaaggcgttgctaaccaatgtgcatggcctgaatctggacaac
tggcaggcggaactggcgcaagcgaacgcgccgttcaatctgggacgcttaattcgcctg
gtgaaagaatatcatctactcaatccggtgattgttgattgtacctccagtcaggcggtg
gccgaccagtatgccgacttcctgcgtgaaggattccatgtggtgacgccaaacaagaaa
gcgaacacctcgtcgatggactactaccatcagctacgtttcgccgccgcgcaatcacgg
cgcaaattcttgtatgacaccaacgtcggcgccggtttgccggtaatcgaaaacctgcaa
aacctgctgaatgcgggtgatgaactgcaaaaattttccggcattctttccgggtcgctc
tcttttattttcggtaaactggaagaggggatgagtctctcacaggcgaccgccctggcg
cgcgagatgggctataccgaacccgatccgcgcgacgatctttccggtatggatgtggcg
cggaaactgttgatcctcgcccgcgagacgggccgcgagctggagctttccgatattgtg
attgaaccggtgttgccggacgagtttgacgcctccggcgatgtgaccgcctttatggcg
catctgccgcagcttgacgacgcgtttgccgcccgtgtggcgaaagctcgtgatgaaggt
aaggtattgcgctatgtgggcaatatcgaagaggatggcgtgtgccgcgtgaagattgcc
gaagttgatggtaacgatccgctcttcaaagtgaaaaacggtgaaaacgcgctggcgttc
tacagccactattatcagcccttgccgttggtgctgcgcggctacggcgcaggcaatgat
gtgacggcggcgggcgtgtttgccgatctgttacggaccctctcatggaagttaggagtt
taa
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