Salmonella enterica subsp. enterica serovar Typhi Ty21a: TY21A_01480
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Entry
TY21A_01480 CDS
T02648
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
sent
Salmonella enterica subsp. enterica serovar Typhi Ty21a
Pathway
sent00230
Purine metabolism
sent01100
Metabolic pathways
sent01110
Biosynthesis of secondary metabolites
Module
sent_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
sent00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
TY21A_01480
Enzymes [BR:
sent01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
TY21A_01480
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AGK65922
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Position
328621..332508
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQ
YGPALSSHTLAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQIDRLERGVAYYIEASTLT
AEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGL
ALAEDEIDYLQEAFTKLGCNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKM
IKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVNRVLHLPTVAEKTFLVTIGDRTV
TGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMS
MKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAMQVLVAARKLLAWHDRSDGGLLVTLAEMAFA
GHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVETLLAQYGLADCVHYLGQALA
GDRFVITANDRTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDADPGLNVK
LSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRI
GLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPH
PERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtctgcattccgtatcaataaactgctg
gcgcgctttcaggctgccaacctccaggtccacaatatatacgctgagtatgtccatttt
gctgacctgaacgccccgttaaatgatagcgagcaggcgcagcttacccgtctgctgcaa
tacggcccggcgcttagcagccatacgctggcgggtaaactcctgttggtcacaccgcgt
cctggtaccatctccccctggtcttcaaaagcaacggatatcgcccacaactgcggcctg
caacagattgaccgtctggagcgcggcgtagcgtactatatcgaggcttcgacgttgacg
gcggaacagtggcgacaagtggccgcagagctgcacgaccgtatgatggagacggtgttc
tcttctttaaccgatgcggaaaaactgtttatccaccatcagcctgcgccggtttccagt
gtcgatctgctgggagaaggccgtcaggcgttaattgacgctaacctgcgtctcggtctg
gcgctggcggaagatgaaatcgactatttgcaggaggcgtttaccaaactgggatgcaac
ccgaacgatatcgaactgtacatgttcgcccaggcgaactccgagcactgccgccacaag
atttttaacgccgactggattatcgacggtaaaccgcagccgaagtcgctgtttaaaatg
attaaaaacaccttcgaaaccacgccggactatgtgctctctgcctataaagacaatgcc
gcggtgatggaaggatctgcggtggggcgctacttcgccgaccacaataccggccgttac
gattttcatcaggagcccgcgcacattctgatgaaggtcgaaacgcataaccacccaacc
gccatctctccgtggccgggggcggcgaccggttccggcggcgaaattcgtgatgaaggc
gccaccgggcgtggcgcgaaaccaaaagccgggctggtaggcttctccgtttccaacctg
cgtattccgggctttgaacagccgtgggaagaggattttggcaagccggaacgtattgtc
accgcgctggatatcatgaccgaaggtccgctgggcggcgcggcgtttaacaacgaattt
ggtcgcccggcgctgaccggttacttccgtacttatgaagagaaagtgaacagccacaat
ggcgaagagctgcgtggctatcacaagccgatcatgctggcgggcgggatcggtaatatc
cgcgccgatcacgtgcagaaaggcgagatcgtcgtaggcgcgaagctgatcgtccttggc
ggcccggcgatgaatatcggcctcggcggcggcgcggcatcgtcaatggcttccggccag
tctgatgcggatctcgattttgcctctgttcagcgcgacaacccggaaatggaacgccgc
tgccaggaagtgatcgaccgctgctggcagttgggcgacgctaacccaatcctgtttatc
catgatgtgggcgcgggcggtctctccaacgccatgccggagctggtaagcgacggcggg
cgcggcgggaaattcgaactgcgcgacattcttagcgacgagccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggagcgctatgtgctggcggtcgcggctgaccagtta
ccgctgttcgatgaactgtgtaagcgcgaacgcgcgccgtatgcggtcattggcgacgct
accgaagaacagcatctctcgttgcatgataaccatttcgacaatcagccgatcgatcta
ccgctggatgtcctgctgggcaaaacaccgaaaatgacccgcgatgtgcaaacattgaag
gcgaaaggcgatgcgctgaaccgcgcggatatcacgattgccgacgcggtaaatcgtgtt
ctgcatctgccgaccgtggcggaaaaaaccttccttgtcactattggcgaccgtaccgtc
accggtatggtggcgcgtgaccagatggttggcccgtggcaggtcccggtagctgactgc
gcggtcactaccgctagcctcgacagctactacggcgaagcgatgtcgattggcgagcgc
gcgccggtggcgctgctggactttgccgcctccgcccgtctggccgtcggtgaagcgttg
actaacattgccgcgacgcagattggcgatatcaagcgcattaagctttccgctaactgg
atggcggcagccggtcatcctggcgaagatgccggtttgtatgacgcggttaaagcggtg
ggagaggaactctgtccgcagcttggcctgacgattccggtgggtaaagattcgatgtcg
atgaaaacccgctggcaggaaggcaacgaacagcgcgaaatgacctcgccgctgtcgctg
gtgatttccgcgtttgcccgcgtggaagacgtgcgtcacacccttacgccgcagctgtca
acggaagataacgccttgctgctgatcgatcttggcaagggccacaacgcgctgggcgca
acggcgttggcgcaggtctatcgtcagcttggcgacaaacccgcggacgtgcgtgacgtt
gcgcaactgaaaggcttctatgacgccatgcaggtgctggttgctgcgcgtaaattactg
gcatggcacgaccgttccgacggcggtctgctggtgacgctggccgagatggcctttgcc
ggccactgcggcgtgcaggtcgatatcgccgcgctgggcgatgaccatctggccgcactg
ttcaacgaggagctgggcggcgtgattcaggtacgcgctgaagacagagacgcggtcgaa
acgctgttggcgcagtacggtcttgctgactgcgtccactaccttggtcaggccctggct
ggcgatcgctttgtgattaccgctaatgatcggacggtattcagcgaaagccgtactacg
ctgcgtgtctggtgggcggaaaccacctggcagatgcagcgtctgcgcgacaatccgcaa
tgtgctgaccaggaacacgaggcgaaagcgaatgatgccgatccgggcctcaacgtgaag
ctgtcgtttgatattaatgaagatatcgccgcgccgtacattgcgacaggcgcacgaccg
aaagtcgctgtactgcgcgagcagggggtgaactctcacgtggagatggcggcggcgttc
catcgtgcgggctttgacgcgattgacgtccatatgagcgacctgctgggcggtcgtatc
ggtctgggcaacttccatgcgctggtggcttgcggcggcttttcctacggcgacgtgctg
ggggcgggcgaaggctgggcgaaatccattctgtttaaccatcgggtgcgcgacgaattc
gaaaccttcttccatcgtccgcagacgctggcgctgggcgtgtgcaacggttgccagatg
atgtcgaatctgcgcgagctgatcccgggcagcgaactgtggccgcgttttgtacgtaac
cattctgaccgcttcgaagcccgcttcagcctggtggaagtgacgcaaagcccatcgctg
ctgctgcaaggaatggtaggctcacagatgccgattgcggtttcccatggggaagggcgc
gttgaggtgcgtgacgatgcgcatcttgccgcgcttgagagcaaaggcctggtcgctctg
cgctacgttgataactttggtaaggtgaccgaaacctatccggctaacccgaacggttcg
ccgaacggcatcacggcggtgacgaccgaaaacggtcgggtgacgattatgatgccgcat
ccggaacgcgtattccgcaccgtcgccaactcctggcacccggaaaactggggcgaggat
agcccgtggatgcgtatcttccgtaatgcgcgtaagcagcttggttaa
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