Serinicoccus hydrothermalis: SGUI_0882
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Entry
SGUI_0882 CDS
T04436
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
serj
Serinicoccus hydrothermalis
Pathway
serj00300
Lysine biosynthesis
serj00550
Peptidoglycan biosynthesis
serj01100
Metabolic pathways
serj01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
serj00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SGUI_0882
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SGUI_0882
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SGUI_0882
Enzymes [BR:
serj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SGUI_0882
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ANS78278
UniProt:
A0A1B1NA40
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Position
complement(961216..962691)
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AA seq
491 aa
AA seq
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MIPLTLGEVARVTGGRVHPGSPEADDLRVTGPVVTDSREAAPGALYVARRGDVADGHDFV
ASAAAQGAVAALTNRVVDDLPCVVVDEDPQRLSARPDRPPYDAVTRAFAALGREVVDRCG
AVGGLRVVGITGSSGKTSTKDLMAQVLPALGPTLAPEASYNSEVGVPLTVCRLTEETAYL
VAEMGASGAGHIAHLTAIAPPQVSVVLNVGSAHLGEFGSRAAIMEAKSELVQALPEGGLA
VLDADDEALVSTMGGYARDAGARVVLVGLGERAQVRATDVVTDERGRASFTLRAPDLGAP
EGGLPVRLQLVGVHHVGNALAVAAVAHEWGMPWDRVARELGAATPRSRWRMQVTERSDGV
TVVNDAYNANPESMRAALQSLAAMRRPDGRTLAVVGGMLELGADSDAEHAGVGALAAQLG
VDHLLTVGELAVPAATAYREAGGARVSSVADRHEARALLDEELLAGDVVLLKSSRDSGLR
MLGDELAGVGG
NT seq
1476 nt
NT seq
+upstream
nt +downstream
nt
gtgatccccctgaccctcggtgaggtcgcccgcgtgaccggcggtcgggtccacccgggt
tcacccgaggcggacgacctgcgcgtcacggggccggtcgtcaccgactcccgcgaggct
gcccccggggcgctctacgtcgcgcgccgcggtgacgtcgccgacggccacgacttcgtc
gcctccgccgccgcgcagggagccgtggccgccctcaccaaccgcgtcgtcgacgacctg
ccgtgcgtggtcgtcgacgaggacccgcagcggctgtcggcacgccccgaccgcccgccc
tacgacgccgtcacccgggccttcgccgcgctcgggcgcgaggtcgtggaccgctgcggc
gccgtgggagggctgcgggtcgtcggcatcaccggctcctcgggcaagacctcgaccaag
gacctcatggcccaggtgctgcccgccctggggcccacgctcgcccccgaggcgtcctac
aactccgaggtcggcgtcccgctcaccgtctgccggctcaccgaggagaccgcctacctc
gtcgcggagatgggtgcctcaggtgccggccacatcgcccacctcacggcgatcgcccct
ccgcaggtctccgtcgtgctcaacgtcgggtccgcgcacctaggcgagttcggctcgcgg
gcggcgatcatggaggcgaagtccgagctcgtgcaggcgctgccggagggcgggctggcc
gtcctcgacgccgacgacgaggcgctggtctcgacgatgggcgggtacgcacgtgacgcc
ggcgcccgggtggtgctcgtgggcctgggcgaacgcgcccaggtgcgcgcgaccgacgtg
gtcaccgacgagcgtggccgcgcctccttcaccctgcgcgcccccgacctgggtgcgccc
gaggggggtctgccggtccggctgcagctcgtgggggtccaccacgtcggcaacgcgctc
gccgtcgccgcggtcgcccacgagtggggtatgccctgggaccgggtcgcccgcgagctc
ggtgccgcgacgccccgctcgcgctggcgcatgcaggtgaccgagcgcagcgacggcgtg
accgtcgtcaacgacgcctacaacgccaaccccgagtccatgcgcgcggcgctgcagagc
ctggccgcgatgcggcggcccgacgggcggaccctcgccgtcgtcggcgggatgctcgag
ctgggcgcggacagcgacgccgagcacgcgggcgtcggcgccctggcggcgcagctcggg
gtcgaccacctgctcaccgtgggggagctcgcggtgccggccgcgacggcataccgggag
gcggggggtgcccgggtgagctcggtcgcggaccgccacgaggcccgcgcgctgctggac
gaggagctcctggcgggggacgtcgtgctgctcaagagcagccgcgactccgggctgcgg
atgctcggcgacgagctggcgggcgtgggcggctga
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