Serratia sp. SCBI: SERRSCBI_03060
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Entry
SERRSCBI_03060 CDS
T03314
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sers
Serratia sp. SCBI
Pathway
sers00260
Glycine, serine and threonine metabolism
sers00261
Monobactam biosynthesis
sers00270
Cysteine and methionine metabolism
sers00300
Lysine biosynthesis
sers01100
Metabolic pathways
sers01110
Biosynthesis of secondary metabolites
sers01120
Microbial metabolism in diverse environments
sers01230
Biosynthesis of amino acids
Module
sers_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sers_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sers_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sers00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SERRSCBI_03060 (thrA)
00270 Cysteine and methionine metabolism
SERRSCBI_03060 (thrA)
00300 Lysine biosynthesis
SERRSCBI_03060 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SERRSCBI_03060 (thrA)
Enzymes [BR:
sers01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SERRSCBI_03060 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SERRSCBI_03060 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AIM20246
LinkDB
All DBs
Position
686769..689228
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI
LPNMSDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA
AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAESTLRIAAAAIP
ADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKDST
DADMPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRAGISVVLITQSSSEYSISF
CVPQGELQRARRALEEEFYLELKDGVLDPLDVMERLAIISVVGDGMRTLRGISARFFSAL
ARANINIVAIAQGSSERSISVVVSNDSATTGVRVSHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIYRQQPWLKQKHIDLRVCGIANSRVMLTNVHGIPLDSWRDALAGAQEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYVDFLADGFHVVTPNKKANTSSMNYYQQLRAAAAGSH
RKFLYDTNVGAGLPVIENLQNLLNAGDELVRFSGILSGSLSFIFGKLDEGLSLSAATLQA
RANGYTEPDPRDDLSGMDVARKLLILAREAGYKLELSNIEVEPVLPPSFDASGDVDTFLA
RLPELDKEFARNVANAAEQGKVLRYVGLIDEGRCKVRIEAVDGNDPLYKVKNGENALAFY
SRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcggaacctcggtagcgaatgcggaacgttttctgcgcgtc
gccgacatcatggagagtaacgcgcgtcagggacaggtagccacggtcttgtccgccccc
gcaaagatcaccaaccatctggtggcgatgatcgacaaaacggtggcgggccaggacatt
ctgccgaatatgagcgacgccgagcggatctttgccgacctgctgagcgggctggcgcag
gcgctgccgggctttgaatacgatcgtttgaaaggcgtggtcgatcaggaattcgcgcag
ctcaaacaggtgctgcatggcgtctcgctgctggggcagtgcccggacagcgtgaacgcg
gcgatcatctgccgtggcgaaaagctctccatcgccatcatggaaggggtgttccgcgcc
aagggttatccggtcacggtgattaacccggtggagaaactgctggcgcagggccactac
ctggagtccaccgtggacatcgccgagtctacgctgcgcatcgccgccgcggcgatcccg
gccgatcacatcgtgctgatggccggtttcaccgccggtaatgacaagggcgagctggtg
gtgctgggccgcaacggctccgactattccgccgcggtgctggccgcctgcctgcgcgcc
gactgttgcgagatctggaccgacgtcgacggcgtttatacctgcgatccgcgcaccgtg
ccggacgccaggttactgaaatcgatgtcgtaccaggaagcgatggagctttcctatttc
ggcgccaaagtattacacccccgcaccatcactccgattgcccagttccaaatcccttgc
ctgattaaaaacacctccaacccgcaggcccccggcacgctgatcggcaaagacagcacc
gatgccgatatgccggtgaagggcatcaccaacctgaacaacatggcgatgatcaacgtc
tccggcccgggcatgaaaggcatggtcggcatggccgcacgggtgttcgccgtgatgtcg
cgcgccggcatttcggtggtgctgatcacccaatcctcttccgaatacagcatcagcttc
tgtgtgccgcagggtgaactgcagcgtgctcgtcgcgcgctggaagaggagttctatctg
gagctgaaagacggcgtgctggatccgctggacgtgatggaacgcctggcgatcatctcg
gtggtcggcgacggcatgcgcaccctgcgcggcatttccgcacgcttcttctccgcgctg
gcgcgcgccaacatcaatatcgtcgccatcgcccaagggtcttccgaacgttccatttcg
gtggtggtcagcaatgattccgccaccaccggcgtgcgcgtcagccaccagatgctgttc
aacaccgatcaggtgatcgaagtgttcgtcatcggcgtcggcggcgtcggcggggcgctg
atcgagcagatctatcgccagcagccgtggctgaagcaaaaacatatcgatctgcgggtg
tgcggcatcgccaactcgcgcgtgatgctgaccaatgtgcacggcatcccgctggacagc
tggcgcgacgcgctggccggcgcgcaggagccgttcaatctcggtcgtctgatccggctg
gtgaaggaatatcacctgctgaacccggtgatcgtcgactgtacctccagtcaggcggtg
gccgatcagtacgtggacttcctggcggacggcttccatgtggtgacgccgaacaaaaag
gccaacacctcgtcgatgaactattatcagcagctgcgcgcggccgccgccggttcgcat
cgcaagttcctgtacgacaccaacgtcggcgccggtctgccggtgattgagaacctgcaa
aatctgctgaacgccggtgatgaactggtgcgtttctccggcatcctgtccggctcgctg
tcctttatcttcggcaagctggacgaagggctgtcgctgtcggcggcgaccctgcaggcc
cgggccaacggctacaccgagccggatccgcgcgacgatctgtccgggatggacgtggcg
cgcaagctgctgatcctggcgcgcgaagccggttataaactggaactgagcaatatcgag
gtcgagccggtgctgccgccgtccttcgacgcgtcgggcgacgtggacaccttcctggcg
cggttgccggagctggataaagagttcgcgcgcaacgtggccaacgctgccgagcaaggc
aaggtgctgcgctatgtcggcctgatcgacgaagggcgctgcaaggtgcgcattgaggcg
gtggatggcaacgatccgttgtataaagtgaagaacggcgagaacgcgctggccttctac
agccgctactatcagccgttgccgctggtgctgcgcggctacggcgccggtaacgatgtg
actgcagcgggcgtattcgccgatctgctgcgcacactgtcatggaagttgggagtttaa
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