Serratia sp. SCBI: SERRSCBI_03415
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Entry
SERRSCBI_03415 CDS
T03314
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sers
Serratia sp. SCBI
Pathway
sers00300
Lysine biosynthesis
sers00550
Peptidoglycan biosynthesis
sers01100
Metabolic pathways
sers01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sers00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SERRSCBI_03415 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SERRSCBI_03415 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SERRSCBI_03415 (murF)
Enzymes [BR:
sers01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SERRSCBI_03415 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Lipase_GDSL_2
Motif
Other DBs
NCBI-ProteinID:
AIM20311
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Position
773177..774538
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AA seq
453 aa
AA seq
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MIPVSLQTLAEVLSAESIGADCQIVEVTTDTRKVTAGCLFVALKGERFDAHDFAADAVAA
GAGALLVSKRLLVDVPQLVVKDTRLALGQLGAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILRECGEVLYTAGNFNNDIGVPLTLLRLEPQHDFAVIELGANHIGEIAYTTALTRPQTAL
VNNLAAAHLEGFGSLAGVAQAKGEIFTGLPADGVAIINADNNDWPHWQSMLGGKTVWRFS
PQAAEGVDFFADDVRVNGAGTQFTLHSPFGTAEIALPLPGRHNVANALAATALAMSVGAT
LEAVRQGLKQLQAVPGRLFPVALAEGKLLLDDSYNANVGSMTAAAQVLAEMPGYRVMVVG
DMAELGAEAEECHRQVGEAARQAGVDKVISVGALSRVLSESSGNGEHYQDKTAVIARVAE
LLSEHAVITVLIKGSRSAAMEQVVRALQEKAPC
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgatccctgtctctcttcagacactggctgaggtattgagcgctgaatcgatcggcgcc
gattgccaaattgtcgaggtgacgacagacacccgcaaggtgaccgccggttgcctgttt
gtggcgctgaaaggcgagcgtttcgacgctcacgactttgcggcggatgccgtagccgca
ggcgccggggcgttgctggtcagtaagcgcttattggtggacgtgccgcagctggtggtg
aaagacacccgtctggcgctggggcagcttggcgcctgggtgcgtcagcaggtgccggcg
cgcgtggtggcgctgaccggctcctcgggcaagacatcggtgaaagaaatgaccgccgcc
attctgcgtgaatgcggcgaagtgctgtataccgccggcaacttcaataacgacatcggc
gtgccgttgacgctgttgcgtctggagccgcagcatgattttgccgtgatagagctgggc
gctaaccacattggcgaaattgcttacaccaccgcattgacgcgtccgcagaccgctttg
gtgaacaacctggcggccgcgcacctggaaggcttcggctcgctggccggcgtcgcccag
gcgaaaggtgaaatctttaccggcctgccggccgacggcgtggcgatcatcaacgccgat
aacaacgactggccgcactggcagagcatgctgggcggcaaaaccgtctggcgcttctcg
ccgcaggccgccgaaggcgtggacttcttcgcggacgacgtgcgggtgaacggcgcaggc
acgcagttcacgctgcacagcccgttcggcaccgccgagatcgcgctgccgctgccgggg
cgccacaacgtggctaacgcgttggcggccacggcgctggcgatgtcggtgggcgctacc
ctggaagcggtgcgtcaggggttaaaacaattgcaggcggtgccggggcgtttgttcccg
gtggcgctggccgaaggcaagctgctgctggacgacagctacaacgccaacgtcgggtcg
atgaccgcggcggcgcaggtgctggcggagatgccgggctaccgcgtgatggtggtcggc
gatatggccgagctgggcgcagaagcggaagagtgccaccgtcaggtgggtgaagccgcc
cgccaggccggggtcgataaagtgatcagcgtcggcgcgttgagccgcgtgctgagcgag
tcttccggcaacggcgaacattatcaggacaagacagcagtgatcgcgcgcgtggcggaa
ttactgtcggaacatgcggtcatcaccgtgttaatcaaaggttcacgtagtgccgcaatg
gagcaggtagtacgcgcgttacaggagaaagcaccatgttag
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