Serratia sp. Tan611: TAN611_0701
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Entry
TAN611_0701 CDS
T10950
Symbol
thrA
Name
(GenBank) fused aspartokinase I; homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sert Serratia sp. Tan611
Pathway
sert00260
Glycine, serine and threonine metabolism
sert00261
Monobactam biosynthesis
sert00270
Cysteine and methionine metabolism
sert00300
Lysine biosynthesis
sert01100
Metabolic pathways
sert01110
Biosynthesis of secondary metabolites
sert01120
Microbial metabolism in diverse environments
sert01230
Biosynthesis of amino acids
Module
sert_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sert_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sert_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sert00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
TAN611_0701 (thrA)
00270 Cysteine and methionine metabolism
TAN611_0701 (thrA)
00300 Lysine biosynthesis
TAN611_0701 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
TAN611_0701 (thrA)
Enzymes [BR:
sert01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
TAN611_0701 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
TAN611_0701 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
CAE1142402
UniProt:
A0A7S4H017
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All DBs
Position
Tan611:735599..738058
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AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADIMESNARQGQVAAVLSAPAKITNHLVAMVEKTLAGQDI
LPNMSDAERIFAELLHGLAQALPGFAHERLKARVEHEFAQLKQVLHGVALLGKCPDSVNA
GIICRGEKLSIAIMEAVFQAKGFPVTVINPVEKLLAQGHYLESTVDIAESTLRIAAMGIP
ADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGAECA
DEDSPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRAGISVVLITQSSSEYSISF
CVPQGELLRARRALGDEFYLELKDGLLEPLDVTENLAIISVVGDGMRTLRGISARFFSAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVSHQMLFNTDQVLEVFVIGTGGVGGAL
IEQIHRQQQWLKQKHIDLRVCGIANSRAMLTNVHGIALDSWREGLAEAQETFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYVDFLADGFHVVTPNKKANTSSMNFYHQLRAAAAGSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELTRFSGILSGSLSFIFGKLDEGMSLSAATLQA
KSNGYTEPDPRDDLSGMDVARKLLILAREAGYNLELSDIEVQSVLPPEFDASGDTDSFLA
RLPELDAAFSRRVADAAEQGKVLRYVGVIEEGRCQVRIDAVDGNDPLYKVKNGENALAFY
SRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcggaacctcggtagcgaatgcggaacgttttctgcgcgtt
gccgatattatggaaagcaatgcccgtcagggacaggtagcggcggtattgtccgcgccg
gcgaagatcaccaaccacttggtggcgatggtggagaaaacgctggccgggcaagacatt
ctgccaaatatgagcgacgcggagcgtattttcgccgagctgctgcacggcctggcgcag
gcgctgccgggctttgcccacgaacgcctcaaggcgcgcgtcgagcatgagtttgcgcag
ctcaagcaggtgctgcacggcgtggcgctgctgggtaaatgcccggacagcgtgaacgcc
ggcattatctgccgcggtgaaaaactgtcgatagccattatggaagcggtattccaggcg
aaaggtttcccggtgaccgtgatcaatccggtggagaagctgctggcgcaggggcactat
ctggaatccaccgtcgatatcgccgaatccacactgcgcatcgccgcaatgggcattccg
gctgaccatatcgtgctgatggccggcttcaccgccgggaatgacaagggcgagctggta
gtgctgggacgcaacggttccgactactccgccgcggtgctggcggcctgcctgcgcgcc
gattgctgtgagatctggaccgatgttgacggggtatatacctgcgatccgcgcaccgtg
ccggacgccaggctgctgaagtcgatgtcgtatcaggaggcgatggagctgtcctatttc
ggcgccaaagttctccacccccgcaccattacccccatcgcccagttccagatcccctgc
ctgattaaaaatacctccaacccgcaggcgcccggtacgctgatcggcgccgagtgcgcg
gatgaagattcaccggtgaaaggtatcaccaacctgaataatatggcgatgatcaacgtc
tccggcccgggcatgaaaggcatggtcggcatggcggcgcgggtgtttgccgtgatgtca
cgcgccggtatctcggtggtgctgatcacccagtcctcctctgaatacagcatcagcttc
tgcgtgccgcagggcgagctgctgcgcgcgcgccgcgcgctgggcgacgagttttatctg
gagctgaaagacggcctgctggagccgctggatgtgacggaaaatctggcgattatctcg
gtggttggcgacggcatgcgcaccctgcgcggtatttcggcgcgtttcttctccgcgctg
gcccgcgccaatatcaatatcgtcgctatcgcccagggatcgtccgaacgctccatctcg
gtggtggtcagcaacgatgatgccaccaccggcgtacgcgtcagtcatcagatgctgttc
aacaccgaccaggtgctggaagtctttgttatcggcaccggcggcgtcggcggcgcgctg
atcgagcagattcaccgccagcagcagtggctgaagcaaaagcatatcgatctgcgggtg
tgcggcattgccaactcgcgtgccatgctgaccaatgtgcacggcattgcgctggacagc
tggcgtgaagggctggcggaagcacaggagaccttcaaccttgggcgactgattcgtctg
gtgaaggagtatcacctgctgaacccggtgattgtcgactgtacttccagccaggcggtg
gccgatcagtatgtcgacttcctggccgacggcttccacgtggtgacgccgaacaagaag
gccaacacctcgtcgatgaatttctatcatcagctgcgcgccgccgccgcgggctcgcgc
cgcaaattcctctatgacaccaacgttggcgccgggctgccggtgattgaaaacctgcag
aacctgctgaacgccggcgatgaactgacgcgtttctccggtattttgtctggttcactg
tcgtttatcttcggcaagctggatgagggcatgtcgctgtcggcggcgacgctgcaggcg
aagagcaacggctataccgaaccggacccgcgcgacgatctgtccgggatggatgtcgcc
cgtaaattgttgattctggcgcgtgaagcgggttacaacctggagctgagcgatatcgag
gtgcaatcggtgctgccgccggagtttgatgccagcggcgataccgacagcttcctggcg
cgtctgccggagctggacgcggcgtttagccgtcgggtggccgatgcggcggagcagggt
aaagtattgcgctatgtcggggtgattgaagaggggcgttgccaggtgcgtattgacgct
gttgatggcaacgatccattgtataaagtgaaaaacggcgagaacgcgctggcgttctac
agccgctattatcagccgctgccgctggtgctgcgcggctatggcgccggtaatgatgtg
acggcagcaggggtattcgccgatctgctgcgcacgctgtcatggaagttgggagtttaa
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