KEGG   Serratia sp. Tan611: TAN611_0841
Entry
TAN611_0841       CDS       T10950                                 
Symbol
cysG
Name
(GenBank) fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase; uroporphyrinogen methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
sert  Serratia sp. Tan611
Pathway
sert00860  Porphyrin metabolism
sert01100  Metabolic pathways
sert01110  Biosynthesis of secondary metabolites
sert01120  Microbial metabolism in diverse environments
sert01240  Biosynthesis of cofactors
Module
sert_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:sert00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    TAN611_0841 (cysG)
Enzymes [BR:sert01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     TAN611_0841 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     TAN611_0841 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     TAN611_0841 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Shikimate_DH ACT_9 Yop-YscD_cpl
Other DBs
NCBI-ProteinID: CAE1142751
UniProt: A0A7S4H029
LinkDB
Position
Tan611:901631..903061
AA seq 476 aa
MDYLPIFADLKQRPVLVVGGGEVAARKVELLARAGAEIRIVAQSLSPELEQHRQSGRINW
LGQAFAPHQLDEVFLVIAATDDAALNAQVYAEADKRRLLANVVDDQPRCSFIFPSIVDRS
PLMVAVSSGGKAPVLARMLREKLEALLPASLGTMAQLAGGFRARVKQQLSSIGARRRFWE
KSLNGRFATLAANEQPQQAQQQLEQDLAAFAAGDEAAQGEIALVGAGPGDVGLLTLRGLQ
VMQQADVVLYDHLVSDEILDLVRRDAERICVGKRAGAHLVIQEETNRLLVELAQQGKRVV
RLKGGDPFIFGRGGEELQVAAAAGIPFQVVPGVTAAAGATAYAGIPLTHRDHAQSVTFIT
GHCRPDGDGLDWADLARARQTLAIYMGTMKAADISQRLIAHGREAQTPVAVISRGTRADQ
QVLTGTLQQLEQLARQAPLPALLVIGEVVELHHQIAWFGHQPQTDGAARPAVVNLA
NT seq 1431 nt   +upstreamnt  +downstreamnt
gtggactatctaccaatatttgccgatctgaaacaacgtccggtactggtcgttggcggc
ggtgaagttgctgcgcgtaaagttgaactgcttgcgcgcgccggggctgaaatacggata
gttgcgcagtcgctctcaccggaacttgaacagcatcgccagtctggacgcatcaactgg
ctggggcaggcgtttgcgccgcaccagttggatgaggtgtttctggtgatcgccgcaacc
gacgacgccgcgttgaacgcccaggtttatgccgaggcggataagcgccgcttgctggcc
aacgtggtggacgatcagccgcgttgctcatttatctttccgtcgattgttgaccgttca
ccgctgatggtggcggtgtcatccggcggcaaggcgccggtgctggcgcggatgctgcgt
gaaaagctggaagcgctgctgccggccagccttggcaccatggcgcaactggctggcggt
tttcgcgctcgggtaaaacagcagctgagttcgatcggcgcacgccgccgtttctgggaa
aaatctcttaacggccgctttgccacgctggcggccaatgagcagccgcagcaggcgcag
caacagctggaacaagacctggccgcgtttgccgccggcgatgaggcagcgcagggcgag
attgcgctggtcggcgccgggccgggcgatgttggtctgctgaccttacgcggcctgcag
gtgatgcagcaggccgacgtggtgctgtacgaccacctggtgagcgacgagattctcgat
ctggtgcgtcgtgacgcggaacgcatctgcgtaggcaaacgcgccggcgcgcatctggtg
atccaggaagagaccaaccgcctgctggtggaactggcgcagcagggcaagcgcgtggtg
cgcctgaagggcggcgacccgtttatctttggccgcggtggcgaagagctgcaggttgcg
gcggcggcggggattccgttccaggtggtgccgggcgtcacggcggcggccggtgcgacg
gcctatgccggcatcccgctgacccaccgtgaccatgcgcagagcgtgacctttatcacc
ggccactgccgtcccgacggcgacgggctggactgggccgacctggcgcgtgcgcgccag
acgctggcgatttacatgggcaccatgaaggcggcggatatcagccagcgcctgatcgcc
catggccgcgaggcgcagaccccggtggcggtgatcagccgtggcacgcgtgccgaccag
caggtgctgaccggtacgctgcagcagttggaacaattagcccgacaggcgccgttgccg
gcgctgttggtgattggcgaagtggtggaactgcaccatcaaatcgcctggtttgggcat
caacctcagacggacggggccgcgcgtcccgccgtagtgaatttggcttaa

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