KEGG   Saccharothrix espanaensis: BN6_23650
Entry
BN6_23650         CDS       T02404                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
sesp  Saccharothrix espanaensis
Pathway
sesp00290  Valine, leucine and isoleucine biosynthesis
sesp00620  Pyruvate metabolism
sesp01100  Metabolic pathways
sesp01110  Biosynthesis of secondary metabolites
sesp01210  2-Oxocarboxylic acid metabolism
sesp01230  Biosynthesis of amino acids
Module
sesp_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:sesp00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    BN6_23650 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    BN6_23650 (leuA)
Enzymes [BR:sesp01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     BN6_23650 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: CCH29683
UniProt: K0JZI4
LinkDB
Position
2506351..2508111
AA seq 586 aa
MPVVRRPRATSSAMTTSETWNRQRPSAMPHHRYRPAHHRVEVPLVDRTWPSRRIDRAPLW
VPVDLRDGNQALAEPMDTARKRRFFDLLITVGFTEIEVGYPSASRTDFEFVRHLATSGAV
PDDVTVVVFTPARHDLIDRTVDSVRGLPNVVVHLYTATAPTWRDVVLGRSRAELHELILD
AAGHLARRVGDRPGVRFQFSPEVFNLTEPDYVLEVCDSLTALWDAGPDRPVVHNLPVTVE
IATPNVYADQIEYMDRHLARRESVILSVHPHNDRGTGVACAELALLAGAQRVEGCLFGNG
ERTGNVDLVTLALNLYTQGVDPMLDFSDIDAVREVVEHCNRLPVHQRHPYGGDLVHTAFS
GTHQDAIAKGLAHHAKRAAELGVPAAGAPWDVPYLPIDPGDLGRTYEEVIRINSQSGKGG
IAHLLHRHHGLDLPQAMRPDFSRMVQEVTDGTGRELAHEELRKLFHTNYITPAHEGVVTL
GSWSAVETDGEHRFSCALAVDGREGSYEGVGNGPLSAFTDALRAAGIAVDILAYSEHATD
TGPDSPAAAYARCRVDGVERWGSGWDTSILTASVHAVLAAVNRARS
NT seq 1761 nt   +upstreamnt  +downstreamnt
gtgccggtcgtccgccgaccgagagcgacctcctccgccatgaccacgtccgagacctgg
aaccggcagcgcccgagcgcgatgccgcaccaccgctaccggcccgcccaccaccgggtc
gaggtgcccctcgtggaccgcacctggccgtcgcgccggatcgaccgggcaccgctctgg
gtgccggtcgacctgcgggacggcaaccaggcgctggccgaaccgatggacaccgcccgc
aagcgccggttcttcgacctgctgatcaccgtgggcttcaccgagatcgaggtcggctac
ccgtcggccagccggaccgacttcgagttcgtccggcacctggccacgagtggcgcggtg
cccgacgacgtgaccgtggtcgtgttcaccccggcccgccacgacctgatcgaccgcacg
gtcgactccgtccgagggctgccgaacgtcgtcgtgcacctctacacggccaccgcgccg
acgtggcgggacgtcgtcctcggccggtcccgcgccgagttgcacgagctgatcctcgac
gccgccggccacctcgcccgacgggtcggcgaccggccgggcgtgcggttccagttctcg
cccgaggtcttcaacctcaccgagcccgactacgtgctggaggtgtgcgacagcctgacc
gcgctgtgggacgcgggcccggaccggccggtggtccacaacctgccggtgaccgtggag
atcgccacgcccaacgtgtacgccgaccagatcgagtacatggaccgccacctggcccgg
cgcgagtcggtgatcctgtccgtgcacccgcacaacgaccggggcacgggcgtggcgtgc
gccgaactcgcgctgctggcgggcgcgcaacgggtcgagggctgcctgttcggcaacggc
gagcgcaccgggaacgtcgacctggtcacgttggcgctcaacctgtacacgcaaggcgtg
gacccgatgctcgacttctccgacatcgacgccgtgcgcgaggtggtggagcactgcaac
cgcctgcccgtccaccagcggcacccctacggcggcgacctggtgcacaccgcgttctcc
ggaacccaccaggacgcgatcgcgaaaggcttggcgcaccacgcgaaacgggcggccgaa
ctcggtgtgccggcggcgggagcgccgtgggacgtgccctacctgccgatcgacccgggc
gacctcggccgcacctacgaggaggtgatccggatcaactcccagtccggcaagggcggc
atcgcccacctgctgcaccggcaccacgggctggacctgccccaggcgatgcggccggac
ttctcgcgcatggtgcaggaggtgaccgacggcaccggccgggagttggcgcacgaagaa
ctccgaaagttgttccacaccaactacatcacccccgcgcacgagggcgtggtgaccttg
gggtcgtggtccgccgtggagaccgacggcgaacaccggttctcgtgcgcgttggcggtc
gacggtcgtgaaggctcgtacgaaggtgtcggcaacggcccgctctcggcgttcacggat
gcgttgcgcgcggcgggaatcgccgtcgacatcctcgcctattcggagcatgcaacggat
accgggccggacagtcccgctgcggcgtacgcccggtgccgggtggacggcgtggagcgg
tggggatccggctgggacacctcgatcctgaccgcgtccgtgcacgccgtgctggccgcg
gtgaaccgggcccgctcgtga

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