Saccharothrix espanaensis: BN6_23650
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Entry
BN6_23650 CDS
T02404
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sesp
Saccharothrix espanaensis
Pathway
sesp00290
Valine, leucine and isoleucine biosynthesis
sesp00620
Pyruvate metabolism
sesp01100
Metabolic pathways
sesp01110
Biosynthesis of secondary metabolites
sesp01210
2-Oxocarboxylic acid metabolism
sesp01230
Biosynthesis of amino acids
Module
sesp_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sesp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BN6_23650 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BN6_23650 (leuA)
Enzymes [BR:
sesp01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BN6_23650 (leuA)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CCH29683
UniProt:
K0JZI4
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All DBs
Position
2506351..2508111
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AA seq
586 aa
AA seq
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MPVVRRPRATSSAMTTSETWNRQRPSAMPHHRYRPAHHRVEVPLVDRTWPSRRIDRAPLW
VPVDLRDGNQALAEPMDTARKRRFFDLLITVGFTEIEVGYPSASRTDFEFVRHLATSGAV
PDDVTVVVFTPARHDLIDRTVDSVRGLPNVVVHLYTATAPTWRDVVLGRSRAELHELILD
AAGHLARRVGDRPGVRFQFSPEVFNLTEPDYVLEVCDSLTALWDAGPDRPVVHNLPVTVE
IATPNVYADQIEYMDRHLARRESVILSVHPHNDRGTGVACAELALLAGAQRVEGCLFGNG
ERTGNVDLVTLALNLYTQGVDPMLDFSDIDAVREVVEHCNRLPVHQRHPYGGDLVHTAFS
GTHQDAIAKGLAHHAKRAAELGVPAAGAPWDVPYLPIDPGDLGRTYEEVIRINSQSGKGG
IAHLLHRHHGLDLPQAMRPDFSRMVQEVTDGTGRELAHEELRKLFHTNYITPAHEGVVTL
GSWSAVETDGEHRFSCALAVDGREGSYEGVGNGPLSAFTDALRAAGIAVDILAYSEHATD
TGPDSPAAAYARCRVDGVERWGSGWDTSILTASVHAVLAAVNRARS
NT seq
1761 nt
NT seq
+upstream
nt +downstream
nt
gtgccggtcgtccgccgaccgagagcgacctcctccgccatgaccacgtccgagacctgg
aaccggcagcgcccgagcgcgatgccgcaccaccgctaccggcccgcccaccaccgggtc
gaggtgcccctcgtggaccgcacctggccgtcgcgccggatcgaccgggcaccgctctgg
gtgccggtcgacctgcgggacggcaaccaggcgctggccgaaccgatggacaccgcccgc
aagcgccggttcttcgacctgctgatcaccgtgggcttcaccgagatcgaggtcggctac
ccgtcggccagccggaccgacttcgagttcgtccggcacctggccacgagtggcgcggtg
cccgacgacgtgaccgtggtcgtgttcaccccggcccgccacgacctgatcgaccgcacg
gtcgactccgtccgagggctgccgaacgtcgtcgtgcacctctacacggccaccgcgccg
acgtggcgggacgtcgtcctcggccggtcccgcgccgagttgcacgagctgatcctcgac
gccgccggccacctcgcccgacgggtcggcgaccggccgggcgtgcggttccagttctcg
cccgaggtcttcaacctcaccgagcccgactacgtgctggaggtgtgcgacagcctgacc
gcgctgtgggacgcgggcccggaccggccggtggtccacaacctgccggtgaccgtggag
atcgccacgcccaacgtgtacgccgaccagatcgagtacatggaccgccacctggcccgg
cgcgagtcggtgatcctgtccgtgcacccgcacaacgaccggggcacgggcgtggcgtgc
gccgaactcgcgctgctggcgggcgcgcaacgggtcgagggctgcctgttcggcaacggc
gagcgcaccgggaacgtcgacctggtcacgttggcgctcaacctgtacacgcaaggcgtg
gacccgatgctcgacttctccgacatcgacgccgtgcgcgaggtggtggagcactgcaac
cgcctgcccgtccaccagcggcacccctacggcggcgacctggtgcacaccgcgttctcc
ggaacccaccaggacgcgatcgcgaaaggcttggcgcaccacgcgaaacgggcggccgaa
ctcggtgtgccggcggcgggagcgccgtgggacgtgccctacctgccgatcgacccgggc
gacctcggccgcacctacgaggaggtgatccggatcaactcccagtccggcaagggcggc
atcgcccacctgctgcaccggcaccacgggctggacctgccccaggcgatgcggccggac
ttctcgcgcatggtgcaggaggtgaccgacggcaccggccgggagttggcgcacgaagaa
ctccgaaagttgttccacaccaactacatcacccccgcgcacgagggcgtggtgaccttg
gggtcgtggtccgccgtggagaccgacggcgaacaccggttctcgtgcgcgttggcggtc
gacggtcgtgaaggctcgtacgaaggtgtcggcaacggcccgctctcggcgttcacggat
gcgttgcgcgcggcgggaatcgccgtcgacatcctcgcctattcggagcatgcaacggat
accgggccggacagtcccgctgcggcgtacgcccggtgccgggtggacggcgtggagcgg
tggggatccggctgggacacctcgatcctgaccgcgtccgtgcacgccgtgctggccgcg
gtgaaccgggcccgctcgtga
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