Suncus etruscus (white-toothed pygmy shrew): 125999018
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Entry
125999018 CDS
T09902
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2
KO
K03099
son of sevenless
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr01521
EGFR tyrosine kinase inhibitor resistance
setr01522
Endocrine resistance
setr04010
MAPK signaling pathway
setr04012
ErbB signaling pathway
setr04014
Ras signaling pathway
setr04062
Chemokine signaling pathway
setr04068
FoxO signaling pathway
setr04072
Phospholipase D signaling pathway
setr04150
mTOR signaling pathway
setr04151
PI3K-Akt signaling pathway
setr04510
Focal adhesion
setr04540
Gap junction
setr04630
JAK-STAT signaling pathway
setr04650
Natural killer cell mediated cytotoxicity
setr04660
T cell receptor signaling pathway
setr04662
B cell receptor signaling pathway
setr04664
Fc epsilon RI signaling pathway
setr04714
Thermogenesis
setr04722
Neurotrophin signaling pathway
setr04810
Regulation of actin cytoskeleton
setr04910
Insulin signaling pathway
setr04912
GnRH signaling pathway
setr04915
Estrogen signaling pathway
setr04917
Prolactin signaling pathway
setr04926
Relaxin signaling pathway
setr04935
Growth hormone synthesis, secretion and action
setr05034
Alcoholism
setr05160
Hepatitis C
setr05161
Hepatitis B
setr05163
Human cytomegalovirus infection
setr05165
Human papillomavirus infection
setr05200
Pathways in cancer
setr05205
Proteoglycans in cancer
setr05206
MicroRNAs in cancer
setr05207
Chemical carcinogenesis - receptor activation
setr05208
Chemical carcinogenesis - reactive oxygen species
setr05210
Colorectal cancer
setr05211
Renal cell carcinoma
setr05213
Endometrial cancer
setr05214
Glioma
setr05215
Prostate cancer
setr05220
Chronic myeloid leukemia
setr05221
Acute myeloid leukemia
setr05223
Non-small cell lung cancer
setr05224
Breast cancer
setr05225
Hepatocellular carcinoma
setr05226
Gastric cancer
setr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125999018 (SOS2)
04012 ErbB signaling pathway
125999018 (SOS2)
04014 Ras signaling pathway
125999018 (SOS2)
04630 JAK-STAT signaling pathway
125999018 (SOS2)
04068 FoxO signaling pathway
125999018 (SOS2)
04072 Phospholipase D signaling pathway
125999018 (SOS2)
04151 PI3K-Akt signaling pathway
125999018 (SOS2)
04150 mTOR signaling pathway
125999018 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
125999018 (SOS2)
04540 Gap junction
125999018 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
125999018 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
125999018 (SOS2)
04660 T cell receptor signaling pathway
125999018 (SOS2)
04662 B cell receptor signaling pathway
125999018 (SOS2)
04664 Fc epsilon RI signaling pathway
125999018 (SOS2)
04062 Chemokine signaling pathway
125999018 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
125999018 (SOS2)
04912 GnRH signaling pathway
125999018 (SOS2)
04915 Estrogen signaling pathway
125999018 (SOS2)
04917 Prolactin signaling pathway
125999018 (SOS2)
04926 Relaxin signaling pathway
125999018 (SOS2)
04935 Growth hormone synthesis, secretion and action
125999018 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
125999018 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
125999018 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125999018 (SOS2)
05206 MicroRNAs in cancer
125999018 (SOS2)
05205 Proteoglycans in cancer
125999018 (SOS2)
05207 Chemical carcinogenesis - receptor activation
125999018 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
125999018 (SOS2)
05231 Choline metabolism in cancer
125999018 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
125999018 (SOS2)
05225 Hepatocellular carcinoma
125999018 (SOS2)
05226 Gastric cancer
125999018 (SOS2)
05214 Glioma
125999018 (SOS2)
05221 Acute myeloid leukemia
125999018 (SOS2)
05220 Chronic myeloid leukemia
125999018 (SOS2)
05211 Renal cell carcinoma
125999018 (SOS2)
05215 Prostate cancer
125999018 (SOS2)
05213 Endometrial cancer
125999018 (SOS2)
05224 Breast cancer
125999018 (SOS2)
05223 Non-small cell lung cancer
125999018 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
125999018 (SOS2)
05160 Hepatitis C
125999018 (SOS2)
05163 Human cytomegalovirus infection
125999018 (SOS2)
05165 Human papillomavirus infection
125999018 (SOS2)
09165 Substance dependence
05034 Alcoholism
125999018 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125999018 (SOS2)
01522 Endocrine resistance
125999018 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_6
PH_10
IQ_SEC7_PH
PH_13
Motif
Other DBs
NCBI-GeneID:
125999018
NCBI-ProteinID:
XP_049622975
LinkDB
All DBs
Position
2:40348487..40435776
Genome browser
AA seq
1333 aa
AA seq
DB search
MQQAPQPYEFFSDENSPKWRGLLVAALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
DIGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSD
IEKIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQD
ILSPKFNEHFSKLMTRPEVTQHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLK
ACSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPICPFYNRQLRSKHLAIKK
MNEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKANHSQSRLP
GYSSAEYRLKEKFIMRKIQICDKEDTCDCKHAFEIVSKEENTTFAAKSSEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHLSKPGHFESFELMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKKRILD
DAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPDIRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCR
QPPRFARKSNFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRITETDAESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDASNSKGNIKSDDDPPAIPPRQPPPPPKVKPRVPAPTGAFDGP
LHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVNTCPNSP
NTPPSTPSPRVPRRCYVLSSSHNSLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPL
YRLPLLENAETPQ
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccctacgagttcttcagcgacgagaacagcccgaaatggcgg
ggcctcttggtggcggccctgcgcaaggttcaggagcaagtacatcccaatctctcagca
aatgaagagtctctctattatattgaagagctaatttttcagttgctcaataaattatgc
atggctcaaccaaggactgttcaagatgtggaggaacgagttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacaatctgctatagagaaacgaaaacgaaga
aatcctcttttactgcctgtggacaaaatccatccctcattgaaggaagttttagggtac
aaagtcgactaccatgtttctctgtacattgtggctgtactggagtatatctcagctgac
atattgaaattggctggtaattatgtttttaatattcgacattatgaaatatctcagcag
gatattaaagtttcaatgtgtgcagataaggttttaatggacatgtttgatcaggatgat
gacataggtttggtgtctctttgtgaagatgagcctagttcttcaggtgaattaaattat
tatgaccttgtcagaactgaaattgcagaagaaagacagtatctccgggagctaaatatg
atcataaaagtgtttcgagaagctttcctttcagacaggaaactgtttaaaccttctgat
attgaaaagattttcagtaacatttcagatatacatgaattgactgtgaaacttttagga
ttgattgaagatacagttgaaatgactgatgaaagcagtcctcatcccttagctggcagc
tgttttgaagatttggcagaagagcaagcgtttgatccttatgaaacattatcacaggac
attctttcaccaaagtttaatgaacattttagtaagttgatgaccagacctgaagtaact
caacactttcagtccattgctgatggttttaaagaggcagttcgttacgtccttccacgc
cttatgctggtgccagtatatcattgctggcactattttgaattattaaagcaattgaaa
gcatgtagtgaagagcaagaagacagagaatgtttaaaccaagcaattactgcactcatg
aatctccaaggtagtatggatcgaatttacaagcagtattcacctagacgacgacctggg
gatcctatttgccctttttataatcgccaattaagaagcaagcatttggcaattaaaaaa
atgaatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgt
aatgaattcatcatggaaggcccattgacaagaattggtgctaaacatgaacggcatatt
tttctttttgatggcttaatgattagctgtaaagccaatcacagccagtctcgacttcct
ggctatagtagtgcagaatacagattaaaagaaaaatttatcatgaggaaaatacaaata
tgtgataaagaagatacttgtgactgcaaacatgcttttgaaatagtatccaaagaagaa
aacactacttttgctgctaagtcttctgaagagaaaaataattggatggcagcacttatt
tctcttcattatcgtagtactctagatagaatgctagattcagtattattgaaagaagaa
aatgaacaaccactgagattaccaagccctgaagtatatcgttttgtagttaaagactct
gaggaaaacatagtctttgaagacaatttgcaaagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaagattaacttatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacatatcgttcattttgtaagccacaggaattgctaagt
ttactgattgaaaggtttgaaattccagagccagaacctactgaagcagataagttggca
gtagagaaaggcgagcagccaatcagtgcagaccttaaaagatttcgcaaggaatatgtt
caaccggtacaacttaggatcttaaatgtgtttcgtcactgggttgagcatcatttttat
gactttgaaagagatttggagttgctggaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtccatcgctaagataatcaaaagaaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccgcctccaccaattgaa
tggcatctcagcaaaccaggacattttgaatcatttgagcttatgacacttcacccaata
gaaattgcacgtcagctgacactcttggaatctgatctctacagaaaagtccaaccatct
gaacttgtagggagtgtgtggaccaaagaagataaagaaataaattctccaaatttgtta
aaaatgattcgtcataccacaaaccttaccctctggtttgaaaaatgcattgtggaagca
gaaaattttgaggaacgggtggcagtattaagtagaattatagaaattctccaagttttt
caagatttgaataatttcaacggtgtattggagatagtcagtgcagtaaattcagtatct
gtttacagactagatcatacctttgaggcactgcaggaaagaaaaaagagaattttggat
gacgctgtagaactaagtcaagatcactttaaaaaatacctagtaaaactcaagtcaatc
aatccaccttgtgtgcctttttttgggatatatttaacgaatattctgaagactgaagaa
gggaataatgactttttaaaaaagaaagggaaagatttgatcaatttcagtaagagaagg
aaagtagctgaaattactggagaaattcaacagtatcagaatcaaccttactgtttacgg
atagaacccgatataaggaggttctttgaaaatcttaatcccatgggaagtgcttctgaa
aaagagtttacagattatttattcaacaagtcactagaaatcgaaccccgaaattgcaga
caaccacctcgatttgctaggaaatcaaatttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaacacctctagaa
agagaaccatgtaaaataagctttagtcgaattacagaaactgatgctgagtcaacagtg
tcagcaccaacctctccaaatacaccttctactccaccagtatctgcttcttcagacctt
agtgtgtttttggatgtggatctcaacagttcctgtggcagcaatagtatctttgcacca
gtcctcttgccgcattcaaagtcttttttcagttcatgtggtagtttacataaactaagt
gaagagccactgattcctcctccacttcctccacgaaaaaagtttgatcacgatgcttca
aattccaagggaaacataaaatctgatgacgatccccctgctattccaccaagacaacct
cctcctcctccaaaggtgaaacccagagttcctgctccaactggtgcatttgatgggcct
cttcatagtccacctcctccaccaccaagagatcctcttcctgatactcctcctccagtt
ccccttcggcctccggaacactttataaactgtccatttaatcttcagccacctccactg
ggacatctgcacagagatccagactggtttagagacgttaatacatgtcccaattcacca
aacactcctcctagcacaccctctccaagggtacctcgtcgatgctatgtgctcagttct
agtcacaatagtcttgctcatcctcaagctccccctgttccaccaaggcagaattcaagc
cctcatctaccaaaactgccaccaaagacttataaacgggagctttcacatccccccttg
tatagactgcctttgttagaaaatgcagaaactcctcaatga
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