KEGG   Suncus etruscus (white-toothed pygmy shrew): 126006370
Entry
126006370         CDS       T09902                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
setr  Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr01522  Endocrine resistance
setr04010  MAPK signaling pathway
setr04015  Rap1 signaling pathway
setr04068  FoxO signaling pathway
setr04071  Sphingolipid signaling pathway
setr04114  Oocyte meiosis
setr04148  Efferocytosis
setr04218  Cellular senescence
setr04261  Adrenergic signaling in cardiomyocytes
setr04370  VEGF signaling pathway
setr04380  Osteoclast differentiation
setr04517  IgSF CAM signaling
setr04550  Signaling pathways regulating pluripotency of stem cells
setr04611  Platelet activation
setr04613  Neutrophil extracellular trap formation
setr04620  Toll-like receptor signaling pathway
setr04621  NOD-like receptor signaling pathway
setr04622  RIG-I-like receptor signaling pathway
setr04625  C-type lectin receptor signaling pathway
setr04657  IL-17 signaling pathway
setr04658  Th1 and Th2 cell differentiation
setr04659  Th17 cell differentiation
setr04660  T cell receptor signaling pathway
setr04664  Fc epsilon RI signaling pathway
setr04668  TNF signaling pathway
setr04670  Leukocyte transendothelial migration
setr04714  Thermogenesis
setr04722  Neurotrophin signaling pathway
setr04723  Retrograde endocannabinoid signaling
setr04728  Dopaminergic synapse
setr04750  Inflammatory mediator regulation of TRP channels
setr04912  GnRH signaling pathway
setr04914  Progesterone-mediated oocyte maturation
setr04917  Prolactin signaling pathway
setr04926  Relaxin signaling pathway
setr04932  Non-alcoholic fatty liver disease
setr04933  AGE-RAGE signaling pathway in diabetic complications
setr04935  Growth hormone synthesis, secretion and action
setr04936  Alcoholic liver disease
setr05014  Amyotrophic lateral sclerosis
setr05020  Prion disease
setr05022  Pathways of neurodegeneration - multiple diseases
setr05132  Salmonella infection
setr05133  Pertussis
setr05135  Yersinia infection
setr05140  Leishmaniasis
setr05142  Chagas disease
setr05145  Toxoplasmosis
setr05152  Tuberculosis
setr05161  Hepatitis B
setr05163  Human cytomegalovirus infection
setr05167  Kaposi sarcoma-associated herpesvirus infection
setr05169  Epstein-Barr virus infection
setr05170  Human immunodeficiency virus 1 infection
setr05171  Coronavirus disease - COVID-19
setr05205  Proteoglycans in cancer
setr05208  Chemical carcinogenesis - reactive oxygen species
setr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
setr05415  Diabetic cardiomyopathy
setr05417  Lipid and atherosclerosis
setr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:setr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    126006370 (MAPK12)
   04015 Rap1 signaling pathway
    126006370 (MAPK12)
   04370 VEGF signaling pathway
    126006370 (MAPK12)
   04668 TNF signaling pathway
    126006370 (MAPK12)
   04068 FoxO signaling pathway
    126006370 (MAPK12)
   04071 Sphingolipid signaling pathway
    126006370 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    126006370 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    126006370 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    126006370 (MAPK12)
   04218 Cellular senescence
    126006370 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    126006370 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    126006370 (MAPK12)
   04613 Neutrophil extracellular trap formation
    126006370 (MAPK12)
   04620 Toll-like receptor signaling pathway
    126006370 (MAPK12)
   04621 NOD-like receptor signaling pathway
    126006370 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    126006370 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    126006370 (MAPK12)
   04660 T cell receptor signaling pathway
    126006370 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    126006370 (MAPK12)
   04659 Th17 cell differentiation
    126006370 (MAPK12)
   04657 IL-17 signaling pathway
    126006370 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    126006370 (MAPK12)
   04670 Leukocyte transendothelial migration
    126006370 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    126006370 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    126006370 (MAPK12)
   04917 Prolactin signaling pathway
    126006370 (MAPK12)
   04926 Relaxin signaling pathway
    126006370 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    126006370 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    126006370 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    126006370 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    126006370 (MAPK12)
   04722 Neurotrophin signaling pathway
    126006370 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    126006370 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    126006370 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    126006370 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    126006370 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    126006370 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    126006370 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    126006370 (MAPK12)
   05161 Hepatitis B
    126006370 (MAPK12)
   05171 Coronavirus disease - COVID-19
    126006370 (MAPK12)
   05163 Human cytomegalovirus infection
    126006370 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    126006370 (MAPK12)
   05169 Epstein-Barr virus infection
    126006370 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    126006370 (MAPK12)
   05135 Yersinia infection
    126006370 (MAPK12)
   05133 Pertussis
    126006370 (MAPK12)
   05152 Tuberculosis
    126006370 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    126006370 (MAPK12)
   05140 Leishmaniasis
    126006370 (MAPK12)
   05142 Chagas disease
    126006370 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    126006370 (MAPK12)
   05020 Prion disease
    126006370 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    126006370 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126006370 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    126006370 (MAPK12)
   05415 Diabetic cardiomyopathy
    126006370 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    126006370 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    126006370 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    126006370 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    126006370 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:setr01001]
    126006370 (MAPK12)
Enzymes [BR:setr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     126006370 (MAPK12)
Protein kinases [BR:setr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   126006370 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 126006370
NCBI-ProteinID: XP_049627721
LinkDB
Position
4:541634..547405
AA seq 372 aa
MSSSPPPPPPAARRGFYRQEVAKTDWEVRAVYQDLQPVGSGAYGAVCSAVDSRSGLRVAI
KKLYRPFQSELYAKRAYRELRLLKHMRHDNVIGLLDVFTPDESLDDFTDFYLVMPFMGTD
LGKLMKHEKLSDDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLA
RQADSEMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQL
KEIMKVTGTPPEEFVQRLQSAEAKNYMKGLPELEKKDFASILTDASPLAVNLLEQMLVLD
AEQRVTAAEALTHPYFESLHETEDEPKAQKYDESFDDVDRTLEEWKRVTYKEVLSFRPPR
HLATKVSKETAL
NT seq 1119 nt   +upstreamnt  +downstreamnt
atgagctcttcgccgccgccgccgcctccggccgcccgccggggcttctaccgccaggag
gttgccaagaccgactgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctcg
ggcgcctacggcgcagtatgctcggcggtggacagccgcagcggcctcagggtggccatc
aagaagctgtaccggcccttccagtcggagctgtacgccaagcgcgcctaccgggagctg
cgcctgctgaagcacatgcgccacgacaacgtaatcgggctgctggacgtattcacccct
gacgagagcctggatgacttcacggacttctacctggtgatgccgttcatgggcaccgac
ctgggcaagctcatgaaacacgagaagctcagtgacgatcgcatccagttcctcgtctac
cagatgctcaaggggctgaagtacatccatgccgcaggcatcatccacagggacctgaag
cctggaaacctggctgtgaatgaggactgcgagttgaagatcctggacttcggcctggcc
agacaggcggacagcgagatgacgggctacgtggtgactcggtggtaccgggcgcctgag
gtcatcctcaactggatgcgctacacacagacagtcgacatctggtcggtgggctgcatc
atggccgagatgatcaccgggaagacgttgttcaagggcagcgaccacctggaccagctg
aaggagatcatgaaggtgacgggcacccctccggaggagtttgtgcagagactgcagagt
gccgaggccaagaactacatgaaggggctcccggagctggagaagaaggatttcgcttcc
atcctgacagacgcgagccctctggccgtgaacctcctggagcagatgctggtgctagac
gcggagcagcgggtgacggccgcggaggcgctcacccacccctacttcgagtccctgcac
gaaacagaggacgagcccaaggcccagaagtatgacgagtctttcgacgacgtggaccgc
acgctggaggagtggaagcgtgtcacctacaaagaggtgctcagcttcaggcctccgagg
catctggcaaccaaggtttccaaggaaacagccttgtga

DBGET integrated database retrieval system