Suncus etruscus (white-toothed pygmy shrew): 126009622
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Entry
126009622 CDS
T09902
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr00790
Folate biosynthesis
setr01100
Metabolic pathways
setr01240
Biosynthesis of cofactors
setr01523
Antifolate resistance
setr04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
126009622 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
126009622 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
126009622 (FPGS)
Enzymes [BR:
setr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
126009622 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Motif
Other DBs
NCBI-GeneID:
126009622
NCBI-ProteinID:
XP_049630117
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Position
5:15730303..15744962
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AA seq
589 aa
AA seq
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MSRAQGHLRAALSLAGASPRPATTTGVAARRGLSAWPAPQEPGMEYQEAVRTLNTLQTNA
SYLEQVKRQRGDPQTQLEAMECYLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERILR
SYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWHLYHRLEETKDDSSCVSMPAYF
RFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTLEK
IAWQKGGIFKHGVPAFTVPQLDSPLAVLRDRAQQISCPLYLCPPLEVLEEGGPPLTLGLD
GEHQRSNAALALQLARCWLQQQGQQGIGELKESRPSPLRQLPLAPVFQPTVQMRHGLQKT
EWPGRTQVLRHGPLTWYLDGAHTSSSVLACTRWFNQALQSCERQCGESEVRVLLFNSTGD
RDPAALLKLLQPCRFDFAVFCPNLTEVSSTGNADQQNFMVTLDQVLLRCLEHQQLWSRLA
EEQGSPHLWDTPTLESSGPVSLLLAPRSPPAPRPSSLVFSCISHALQWISQGRDPIFHLS
APPGALLNHPVADSGADMLREAGAIHVLVTGSLHLVGGVLKLLQPTLAQ
NT seq
1770 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggctcagggccacctgcgcgcggccctgtccctggcgggggcttctccgcgc
cctgcaacgaccaccggggtggcggcgcggcgaggtctgagcgcgtggcccgcgccgcag
gaaccgggcatggaatatcaggaggcagtacgcacgctcaacactctgcagaccaatgcc
agctacctagaacaggttaagcgccagcgtggagacccgcagacacagctggaggcaatg
gagtgctacttggctcggagtgggctgcaggtggaggacttggaccagttgaacatcatc
catgtcactgggaccaaaggaaagggctctacctgtgccttcactgaacgaattctccgg
agctatggcctgaagacaggattcttcagctcgccgcacttggttcaggtacgtgagcgg
atccgaatcaacgggcagcccatcagtcccgagctcttcaccaagcacttctggcacctc
taccaccgcctcgaggagaccaaggatgacagcagctgtgtctccatgcccgcctacttc
cgcttccttacgctcatggccttccacgtctttctccaagagaaggtagacctggcagtg
gtagaagtgggcatcggcggggcgtatgactgtaccaacattatcaggaagcctgtggta
tgtggggtctcctctctgggcattgaccataccagccttctgggggacaccctggagaag
attgcatggcagaaagggggcatcttcaagcatggcgtgcctgccttcactgttccccag
ctcgacagccccctggccgtgctgagagatcgcgcacagcagatctcttgccctctctac
ctgtgcccaccactagaagtgctggaagaagggggtcccccgctgaccctgggcctggat
ggggagcaccagcgttccaatgcggccttggccttgcagttggcccggtgctggctgcag
cagcaaggccagcagggcatcggagaactgaaggaatccaggccgagccccctacggcag
ctgcccttggcacctgtgttccagcccacagtccagatgcggcacgggcttcagaaaaca
gagtggccaggccggacgcaggtgctgcgccatgggccactcacctggtacctggacggg
gcgcacacctccagcagcgtgttggcttgtacacgttggtttaaccaggcgctgcaaagc
tgcgagaggcagtgtggtgaatctgaagtgcgagtcttgctcttcaactccacgggggac
agggatcccgcagccctgctgaagctgctgcagccctgcaggtttgacttcgctgtgttc
tgcccaaacctgactgaggtatcgtccacaggcaatgcagatcagcagaacttcatggtc
acactggaccaggtgctgctccgctgcctcgaacaccagcaactctggagtcgcctggcc
gaggagcagggtagcccacacctctgggacaccccgacgctggagtccagcgggcccgtg
tcccttctgctggcccctcgctcgccgcctgccccccgccccagctccctggtctttagc
tgcatctcgcatgccttgcagtggatcagtcaaggccgggaccccatcttccatctgtcg
gctcccccaggggccctcctgaaccatcctgtggcagacagtggggcagacatgctgcgg
gaggcgggagccatccatgtgctagtcacagggagtttgcacctggtgggcggcgtgttg
aagctgctgcagcccaccctggcccagtag
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