KEGG   Suncus etruscus (white-toothed pygmy shrew): 126012160
Entry
126012160         CDS       T09902                                 
Symbol
PLD2
Name
(RefSeq) phospholipase D2
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
setr  Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr00564  Glycerophospholipid metabolism
setr00565  Ether lipid metabolism
setr01100  Metabolic pathways
setr04014  Ras signaling pathway
setr04024  cAMP signaling pathway
setr04071  Sphingolipid signaling pathway
setr04072  Phospholipase D signaling pathway
setr04144  Endocytosis
setr04666  Fc gamma R-mediated phagocytosis
setr04724  Glutamatergic synapse
setr04912  GnRH signaling pathway
setr04928  Parathyroid hormone synthesis, secretion and action
setr05200  Pathways in cancer
setr05208  Chemical carcinogenesis - reactive oxygen species
setr05212  Pancreatic cancer
setr05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:setr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    126012160 (PLD2)
   00565 Ether lipid metabolism
    126012160 (PLD2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    126012160 (PLD2)
   04072 Phospholipase D signaling pathway
    126012160 (PLD2)
   04071 Sphingolipid signaling pathway
    126012160 (PLD2)
   04024 cAMP signaling pathway
    126012160 (PLD2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    126012160 (PLD2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    126012160 (PLD2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    126012160 (PLD2)
   04928 Parathyroid hormone synthesis, secretion and action
    126012160 (PLD2)
  09156 Nervous system
   04724 Glutamatergic synapse
    126012160 (PLD2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    126012160 (PLD2)
   05208 Chemical carcinogenesis - reactive oxygen species
    126012160 (PLD2)
   05231 Choline metabolism in cancer
    126012160 (PLD2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    126012160 (PLD2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:setr04131]
    126012160 (PLD2)
Enzymes [BR:setr01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     126012160 (PLD2)
Membrane trafficking [BR:setr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    126012160 (PLD2)
 Endosome - Golgi transport
  Others
   Others
    126012160 (PLD2)
SSDB
Motif
Pfam: PLDc PX PLDc_2 PH
Other DBs
NCBI-GeneID: 126012160
NCBI-ProteinID: XP_049631948
LinkDB
Position
1:complement(153188328..153206323)
AA seq 934 aa
MTATSESLFSSGDDDLDSSQLQMEPDEVDTLKEGEDPADRMHPFLAIYNIQPLKTHPMVF
APGVPVTAQVVGTERYTSGSKVGTCTLYSVQLTHGDFTWTTKKKFRHFQELHRDLLRHKL
LMSLLPLARFAIPYSPDQDAPNTEIPSLPRTSPEGSSRHTSSKQKYLENYLNHLLTMSFY
RNYHAMTEFLEVSQLSFIPDLGCKGLEGVIRKRSGGHRVPGFTCCGRDQVCYRWSKRWLV
VKDSFLLYMCLETGVISFVQLFDPGFEVQVGKKNTEARYGVRIDTSHRSLILKCSSYRQA
LWWGQEITELAQGPGKDFLQFHRHDSYAPPRPRTLARWFVNGAGYFAAVADAILRAQEEI
FITDWWLSPEVYLKRPAHSDDWRLDIMLKKKAEEGVRISILLFKEVELALGINSGYSKRT
LMMLHPNIKVMRHPDYVTLWAHHEKLLVVDQIVAFLGGLDLAYGRWDDLHYRLTDLGKSS
ESVSPQSPTSCSDPVSSLDLSNNQCFWLGKDYSNLITKDWVQLDRPFEDFIDRETMPRMP
WRDVGVVVHGPSARDLARHFIQRWNFTKTTKAKYKSSAYPYMLPKSISTAHHLPFTLPGG
QCATVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGD
EIVDRILKAHKQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHYTYRTLCRGEYSILH
RLKAAMGTAWRDYMSICGLRTHGELAGHPVSELIYIHSKMLIADDRTVIIGSANINDRSL
LGKRDSELAVLIEDTEMEPSLMDGVEYQAGRFALSLRKHCFSVILGADAQPNLDLRDPIC
DDFFQLWQDTAENNANIYEQIFRCLPSNATRSLRVLREYVAVEPLATVSPSLAQSELSHV
KGHLVHFPLKFLEDESLLPPLGSKEGVMPLEVWT
NT seq 2805 nt   +upstreamnt  +downstreamnt
atgacggccacctccgagagcctcttctcttctggggacgacgacctggactccagccag
ttacagatggaacccgatgaggtggacactctgaaggagggagaggacccagctgaccgg
atgcacccctttctggccatctacaacattcagcctctgaaaacacaccctatggtgttt
gcccctggagtccctgtcacagcccaggtggtgggcaccgaaagatacacgagtggatcc
aaggtgggaacatgcactctgtattctgtccaattgactcatggtgactttacctggaca
accaagaagaaatttcgccacttccaggaactgcatcgggatcttctgagacacaaactc
ttgatgagtctactccctttggctcgctttgccatcccctattctccagatcaagatgca
cccaacacagagataccatctctcccccgaacaagtcctgagggctcctctaggcacaca
tccagcaagcagaaatacctggaaaattacctcaaccacctcttgaccatgtctttctac
cgaaactaccatgccatgacagagttcttggaagtcagtcagctgtcctttatcccagat
cttggctgcaaaggactggagggagtgatccggaagcgctcaggcggccaccgtgttcct
ggcttcacctgctgtggccgagaccaagtttgttatcgctggtccaagaggtggttggtg
gtgaaggattcctttctgctgtacatgtgcctcgagacaggtgtcatctcatttgttcag
ctctttgaccctggtttcgaggtacaggttggaaaaaagaacacagaggcacggtatggg
gtccggatcgacacctctcacagatcccttattctcaaatgcagcagctaccgacaggca
ctgtggtggggtcaggagatcactgagctggctcagggccctggcaaagatttcttacag
tttcaccggcatgacagctatgccccaccccggcctagaaccctggctcgatggtttgtg
aatggggcaggctattttgctgcagtggcagatgccatccttcgagctcaagaggagatt
ttcatcacagattggtggttgagtcctgaggtatacctgaagcgtccagcccattcagat
gactggagactggacattatgctcaaaaagaaggcggaggagggtgtccgtatatctata
ctgctgtttaaagaagtggagttggccttgggcatcaatagtggctacagcaaaaggacc
ctgatgatgctgcaccccaacataaaggtgatgcgtcacccagactatgtgacactatgg
gcccatcatgaaaagctcctagtggtagaccaaatagtggccttcttaggtgggctggac
cttgcctatggccgctgggatgacctgcactaccgactgactgatcttgggaagtcttct
gaatcagtttccccacagtctcccacctcctgctcagaccctgtatcttccctggatctc
tctaataaccagtgcttctggctgggcaaggactatagcaatcttatcactaaggactgg
gtgcaactggatcgtccttttgaagattttattgacagggagaccatgccccggatgcca
tggcgagatgttggagtggtagtgcatggaccctctgcccgcgaccttgcccggcacttc
atccagcgctggaacttcacaaagactaccaaggccaagtacaagtcatctgcatacccg
tacatgttgcccaagtccatcagcactgcacatcatctccctttcacgctcccaggtggg
cagtgtgccactgtacaggtcttacggtcagtggaccgctggtcagcgggcactctggaa
aactccatcctcaatgcttacttgcataccatcagggagagccagcacttcctctacatt
gagaatcagttcttcattagctgctcagatgggcgaacagttctgaacaaggtgggcgat
gaaattgtggacagaatcctcaaggcccacaaacagggccagtgcttccgagtctatgtg
cttttgcccctgctccctggttttgagggggacatctctactggtggtggcaattccatc
caggccattttgcactatacttacagaacattatgtcgtggggaatattcaatcctacat
cgcctcaaagcagccatggggacagcatggcgagactatatgtccatctgtgggcttcgc
acacatggagagctggctggacacccagtctctgagctcatctatattcacagcaagatg
ctgattgcagatgaccggacagtcattattggctctgcaaacatcaatgaccggagcttg
ctggggaagcgcgatagtgagctggccgtgctgattgaggacacagaaatggagccatcc
ctcatggatggtgtggagtatcaggcgggcagatttgccttgagtttgcggaagcactgt
ttcagtgtgattctaggggcagatgcccaacccaacttggatcttcgagaccccatctgt
gatgactttttccaattgtggcaagacacagctgagaataatgctaatatctatgagcag
atctttcgttgcctaccatccaatgccacacgctccctccgggttctccgggaatatgta
gctgtggagcccctagccacagtcagcccttccttggcacagtctgagctcagtcatgtc
aagggccatctggttcacttccctctcaagttcctggaggatgagtctttgctgcctccc
ctggggagtaaagagggtgtgatgcctctggaagtgtggacatag

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