Suncus etruscus (white-toothed pygmy shrew): 126016565
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Entry
126016565 CDS
T09902
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr04140
Autophagy - animal
setr04141
Protein processing in endoplasmic reticulum
setr04210
Apoptosis
setr04932
Non-alcoholic fatty liver disease
setr05010
Alzheimer disease
setr05012
Parkinson disease
setr05014
Amyotrophic lateral sclerosis
setr05016
Huntington disease
setr05017
Spinocerebellar ataxia
setr05022
Pathways of neurodegeneration - multiple diseases
setr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
126016565 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
126016565 (ERN1)
09143 Cell growth and death
04210 Apoptosis
126016565 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
126016565 (ERN1)
05012 Parkinson disease
126016565 (ERN1)
05014 Amyotrophic lateral sclerosis
126016565 (ERN1)
05016 Huntington disease
126016565 (ERN1)
05017 Spinocerebellar ataxia
126016565 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
126016565 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
126016565 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
126016565 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
setr01001
]
126016565 (ERN1)
Enzymes [BR:
setr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
126016565 (ERN1)
Protein kinases [BR:
setr01001
]
Serine/threonine kinases: Other
IRE family
126016565 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Kdo
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
126016565
NCBI-ProteinID:
XP_049635003
LinkDB
All DBs
Position
1:complement(195196463..195272351)
Genome browser
AA seq
968 aa
AA seq
DB search
MPARRLPLLLLLALLWPGPGILGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVVDLLTGEKQQTLSSAFTDSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASRPEEDLDYHMSHFVSNGDGLVVTVDSDSGDVLWIQNYASPVVAFYVWQREGLR
KVLHVNVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLMPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTVGDKGECVITPSTDLKFDPALKGKHKFNNYLRN
YWLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSETKAFKDIIHLVDQASETAPTT
MSQDVEEKFAHAPAKPEAPVDSVLKDIATIVLSTFLLIGWVAFIITYPLSIQQQRHLQKI
QLLHHHQQLPFRPSGDGMPGAEPLDSSGLYSESSATSSPSTSPRASNHSLPSSGSTSRAG
PFLEQDEEDGETSVVMVGKISFCPKDVLGHGAEGTIVYRGMFDSRAVAVKRILPECFSFA
DREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPIALL
QQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRCS
GVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGA
YSLDCLQPDKHEDVVALELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRI
EKESLDGAIVKQLERGGRAVVRLDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKH
HYRELPAEVQETLGSLPDDFVRYFTSRFPHLLTHTYRAMELCNHERPFQPYYYHEPPEAR
PPVTPDAL
NT seq
2907 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctaccgctcctgctgctgctggcgctgctgtggcccggccccggg
attttgggcagccccagcacagtgacacttcccgagaccttgttgtttgtgtccaccctg
gatggaagcttgcatgcggtcagcaagaggacaggctccatcaaatggactttaaaagaa
gatccagttctgcaggttccaacacacgttgaagagcctgcctttctcccggatcccaat
gatggcagcttgtacacacttggaggcaagaataatgaagggctgacgaaacttccgttt
accatcccagagttggtccaggcatctccgtgccgaagctcagatgggatcttgtacatg
gggaagaagcaggacatctggtacgtcgtggacctgttgaccggagagaagcagcagacg
ctctcgtcggccttcacggacagtctctgcccctccacatcgctgctgtaccttgggcgg
acagagtacaccatcactatgtatgacaccaagactcgggagctccgctggaacgccacc
tacttcgactacgctgcctcaaggcccgaggaagacctggactaccacatgtcccacttt
gtgtccaacggcgacgggctggtggtgacggtggacagcgactcgggggacgtgctgtgg
atccagaactacgcgtccccagtggtggccttctacgtgtggcagcgcgaggggcttcgg
aaggtgctgcatgtcaacgtggcggtagagacgctgcgctacctgaccttcatgtcgggg
gaggtgggccgtatcaccaagtggaagtaccccttccccaaggagaccgaggccaagagc
aagctgatgccgacgctgtatgtggggaaatactctaccagcctctacgcctccccatcc
atggtgcatgagggggtcgcagtggtgccccgaggcagcacccttcccttgctggaaggc
ccccagactgacggggtcaccgtaggggacaaaggagaatgtgtgatcacccccagcaca
gacctcaagttcgaccccgcgctcaaagggaaacacaagttcaacaactacctccgcaac
tactggcttctcatcgggcaccatgagacaccgctgtctgcgtccaccaagatgctggag
aggttccccaataacctacccaaacaccgggaaaacgtgattcctgctgactcggagaca
aaggccttcaaggatatcatccacctggttgaccaggcttcagagacagcacctaccacc
atgtctcaggatgtggaggagaagtttgcgcatgcacccgccaagcccgaggcccccgtg
gactctgtgctcaaggacatcgccaccattgtgctgagcaccttcctcctcatcggttgg
gtggccttcatcatcacctacccgctgagcattcagcagcagcggcatctccagaaaatc
caactcctgcaccaccaccagcagctgcccttccgcccatcgggagacgggatgccgggt
gctgagcccctggactcctctggcctgtattcagaaagctcggccaccagcagtcccagc
acgtcgccccgtgcctccaaccactcgctgccctccagtggctccacgtcccgggcaggc
cctttcctggagcaggatgaggaagatggagaaaccagcgtggtgatggtggggaaaatc
tccttctgtcccaaggacgtgctgggccacggagcggagggcaccattgtgtaccggggc
atgtttgacagccgtgctgtggccgtcaagaggatcctccctgagtgcttcagctttgcg
gaccgagaggtgcagctgctgcgggagtcggacgagcaccccaatgtcatccgctacttc
tgcacagagcgtgaccgccagttccagtacatcgccatcgaactatgtgcggccacgctg
caggagtatgtggagcagaaagactttgcacacctgggcctggaacccatcgcccttctg
cagcagaccacatcaggcctggcacacctgcactctctcaacatagtccacagagacctg
aagccccacaacatcctcctgtctatgcccaacgcgcacggcaggatcaaggccatgatc
tctgactttggcctctgcaagaaactggctgtgggcagacatagcttcagccgctgctcg
ggggtgcctggcacggagggctggattgcacccgagatgctgagcgaagactgcaaggaa
aaccccacctacactgtggacatcttctcagcaggctgcgtcttctactacgtcatttcc
gagggcagccacccattcggcaagtccctgcagcggcaggccaacatcctcctgggcgcc
tacagcctcgactgcctgcagcccgacaagcatgaagacgttgtggccctggagctgata
gagaagatgattgccatggaccctcagaaacggccgtcagccaagcacgtgctgaagcac
cccttcttctggagcctggaaaagcagcttcagttcttccaggacgtgagtgaccggatc
gagaaggaatccctggacggcgccatcgtgaagcagctggagagaggcgggcgggcggtg
gtgaggctggactggagggagaacatcaccgtcccgctccagacagatctacgcaaattc
agaacctataaaggtggctctgtccgggatctcctccgagccatgagaaataagaagcac
cattaccgggagttgccggcggaggtgcaggagacgctggggtccctccccgatgacttc
gtgcgctatttcacgtcacgcttcccacacctgctcacgcacacctaccgtgccatggag
ctgtgcaaccacgagcggcccttccagccctactactaccacgagccccccgaggcccgg
ccccccgtgactcctgacgccctctga
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