KEGG   Suncus etruscus (white-toothed pygmy shrew): 126017330
Entry
126017330         CDS       T09902                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X1
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
setr  Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr01521  EGFR tyrosine kinase inhibitor resistance
setr01522  Endocrine resistance
setr04012  ErbB signaling pathway
setr04015  Rap1 signaling pathway
setr04062  Chemokine signaling pathway
setr04081  Hormone signaling
setr04137  Mitophagy - animal
setr04144  Endocytosis
setr04360  Axon guidance
setr04370  VEGF signaling pathway
setr04510  Focal adhesion
setr04520  Adherens junction
setr04530  Tight junction
setr04540  Gap junction
setr04611  Platelet activation
setr04613  Neutrophil extracellular trap formation
setr04625  C-type lectin receptor signaling pathway
setr04727  GABAergic synapse
setr04750  Inflammatory mediator regulation of TRP channels
setr04810  Regulation of actin cytoskeleton
setr04912  GnRH signaling pathway
setr04915  Estrogen signaling pathway
setr04917  Prolactin signaling pathway
setr04919  Thyroid hormone signaling pathway
setr04921  Oxytocin signaling pathway
setr04926  Relaxin signaling pathway
setr05100  Bacterial invasion of epithelial cells
setr05135  Yersinia infection
setr05152  Tuberculosis
setr05161  Hepatitis B
setr05163  Human cytomegalovirus infection
setr05167  Kaposi sarcoma-associated herpesvirus infection
setr05168  Herpes simplex virus 1 infection
setr05203  Viral carcinogenesis
setr05205  Proteoglycans in cancer
setr05207  Chemical carcinogenesis - receptor activation
setr05208  Chemical carcinogenesis - reactive oxygen species
setr05219  Bladder cancer
setr05417  Lipid and atherosclerosis
setr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:setr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    126017330 (SRC)
   04015 Rap1 signaling pathway
    126017330 (SRC)
   04370 VEGF signaling pathway
    126017330 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    126017330 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    126017330 (SRC)
   04137 Mitophagy - animal
    126017330 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    126017330 (SRC)
   04520 Adherens junction
    126017330 (SRC)
   04530 Tight junction
    126017330 (SRC)
   04540 Gap junction
    126017330 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    126017330 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    126017330 (SRC)
   04613 Neutrophil extracellular trap formation
    126017330 (SRC)
   04625 C-type lectin receptor signaling pathway
    126017330 (SRC)
   04062 Chemokine signaling pathway
    126017330 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    126017330 (SRC)
   04915 Estrogen signaling pathway
    126017330 (SRC)
   04917 Prolactin signaling pathway
    126017330 (SRC)
   04921 Oxytocin signaling pathway
    126017330 (SRC)
   04926 Relaxin signaling pathway
    126017330 (SRC)
   04919 Thyroid hormone signaling pathway
    126017330 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    126017330 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    126017330 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    126017330 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    126017330 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    126017330 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    126017330 (SRC)
   05203 Viral carcinogenesis
    126017330 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    126017330 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    126017330 (SRC)
   05168 Herpes simplex virus 1 infection
    126017330 (SRC)
   05163 Human cytomegalovirus infection
    126017330 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    126017330 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    126017330 (SRC)
   05152 Tuberculosis
    126017330 (SRC)
   05100 Bacterial invasion of epithelial cells
    126017330 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    126017330 (SRC)
   05418 Fluid shear stress and atherosclerosis
    126017330 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    126017330 (SRC)
   01522 Endocrine resistance
    126017330 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:setr01001]
    126017330 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:setr04131]
    126017330 (SRC)
Enzymes [BR:setr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     126017330 (SRC)
Protein kinases [BR:setr01001]
 Non-receptor tyrosine kinases
  SRC family
   126017330 (SRC)
Membrane trafficking [BR:setr04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    126017330 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    126017330 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    126017330 (SRC)
  Macropinocytosis
   Kinases
    126017330 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 126017330
NCBI-ProteinID: XP_049635182
LinkDB
Position
9:complement(15426579..15447044)
AA seq 551 aa
MGSNKSKPKEASQRRRSLEPTENAHGPGSAFPATQTPCKPSADSHRGPNATFTPAAAEPK
LFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKVDV
SQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLL
LNSENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSS
LQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVW
MGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMS
KGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKV
ADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVP
YPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTS
TEPQYQPGENL
NT seq 1656 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggaggccagccagcggcgccgcagcctggagccc
accgagaatgcccacggaccgggcagcgccttccccgccacacagaccccctgcaagcct
tccgccgacagccaccgcggccccaatgccaccttcaccccggcagctgctgagcccaag
ctatttgggggcttcaactcttcggacaccgtcacctccccacagagggcagggcctctg
gctgggggtgtgactaccttcgtggcactctatgactacgagtccagaacagagactgac
ctgtccttcaagaaaggagagcggctccagattgtcaacaacacgaggaaagtggatgtc
agccagacctggttcacattcagatggctgcaaagagagggggactggtggctggcccac
tcgctcagcaccgggcagaccggctacatccccagcaactacgtggcaccctctgactcc
atccaggctgaagaatggtactttggcaagatcaccagacgggagtcagagaggttgttg
ctcaactcggagaaccccagaggtactttcctggttcgtgaaagtgagaccacgaaaggc
gcctactgcttgtctgtgtccgacttcgacaatgccaagggcctcaacgtgaagcactat
aagatacgtaaactggacagtggcggcttctacatcacctcccgcacccagttcagcagc
ctgcagcagctggtggcctactactccaaacatgctgacggcttgtgccaccgactcacc
accgtgtgccccacgtccaagccacagacacaaggcctggccaaggacgcctgggagatc
ccccgggagtcgctgcggctggaagtcaaactgggccagggttgcttcggagaggtgtgg
atgggaacgtggaatggcacaacccgggtggccatcaagaccctgaagccgggcactatg
tccccggaggccttcttgcaggaagcgcaggtcatgaagaagctgcggcacgagaagctg
gtacagttgtatgcggtggtgtccgaggagcccatctacattgtcaccgagtacatgagc
aaagggagcttgctggacttccttaagggcgagacgggcaagtacctgcggcttcctcag
ctggtggacatggctgcacagattgcctctggcatggcgtatgtggagcggatgaactac
gtgcaccgggacctccgtgccgccaacatcctggtgggcgagaacctcgtgtgcaaagta
gccgacttcggactggcacggctcatcgaagacaatgagtacacagcccggcaaggtgcc
aagtttcccatcaagtggacagcgcctgaagccgccctctatggccgattcaccatcaag
tcggatgtgtggtcattcggcatccttctgactgagctcaccaccaaaggccgagtaccc
tacccagggatggtgaaccgggaagtgctggaccaggtggaacgtggctaccgcatgcca
tgcccacccgagtgccccgagtccctgcacgacctcatgtgccagtgctggcggaaggag
ccagaggaacggcccaccttcgagtacctgcaggccttcctggaggattacttcacgtcc
accgagccccagtaccagcctggcgagaacttatag

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