Suncus etruscus (white-toothed pygmy shrew): 126023864
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Entry
126023864 CDS
T09902
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr01521
EGFR tyrosine kinase inhibitor resistance
setr01522
Endocrine resistance
setr04010
MAPK signaling pathway
setr04012
ErbB signaling pathway
setr04014
Ras signaling pathway
setr04062
Chemokine signaling pathway
setr04068
FoxO signaling pathway
setr04072
Phospholipase D signaling pathway
setr04150
mTOR signaling pathway
setr04151
PI3K-Akt signaling pathway
setr04510
Focal adhesion
setr04540
Gap junction
setr04630
JAK-STAT signaling pathway
setr04650
Natural killer cell mediated cytotoxicity
setr04660
T cell receptor signaling pathway
setr04662
B cell receptor signaling pathway
setr04664
Fc epsilon RI signaling pathway
setr04714
Thermogenesis
setr04722
Neurotrophin signaling pathway
setr04810
Regulation of actin cytoskeleton
setr04910
Insulin signaling pathway
setr04912
GnRH signaling pathway
setr04915
Estrogen signaling pathway
setr04917
Prolactin signaling pathway
setr04926
Relaxin signaling pathway
setr04935
Growth hormone synthesis, secretion and action
setr05034
Alcoholism
setr05160
Hepatitis C
setr05161
Hepatitis B
setr05163
Human cytomegalovirus infection
setr05165
Human papillomavirus infection
setr05200
Pathways in cancer
setr05205
Proteoglycans in cancer
setr05206
MicroRNAs in cancer
setr05207
Chemical carcinogenesis - receptor activation
setr05208
Chemical carcinogenesis - reactive oxygen species
setr05210
Colorectal cancer
setr05211
Renal cell carcinoma
setr05213
Endometrial cancer
setr05214
Glioma
setr05215
Prostate cancer
setr05220
Chronic myeloid leukemia
setr05221
Acute myeloid leukemia
setr05223
Non-small cell lung cancer
setr05224
Breast cancer
setr05225
Hepatocellular carcinoma
setr05226
Gastric cancer
setr05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
126023864 (SOS1)
04012 ErbB signaling pathway
126023864 (SOS1)
04014 Ras signaling pathway
126023864 (SOS1)
04630 JAK-STAT signaling pathway
126023864 (SOS1)
04068 FoxO signaling pathway
126023864 (SOS1)
04072 Phospholipase D signaling pathway
126023864 (SOS1)
04151 PI3K-Akt signaling pathway
126023864 (SOS1)
04150 mTOR signaling pathway
126023864 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
126023864 (SOS1)
04540 Gap junction
126023864 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
126023864 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
126023864 (SOS1)
04660 T cell receptor signaling pathway
126023864 (SOS1)
04662 B cell receptor signaling pathway
126023864 (SOS1)
04664 Fc epsilon RI signaling pathway
126023864 (SOS1)
04062 Chemokine signaling pathway
126023864 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
126023864 (SOS1)
04912 GnRH signaling pathway
126023864 (SOS1)
04915 Estrogen signaling pathway
126023864 (SOS1)
04917 Prolactin signaling pathway
126023864 (SOS1)
04926 Relaxin signaling pathway
126023864 (SOS1)
04935 Growth hormone synthesis, secretion and action
126023864 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
126023864 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
126023864 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
126023864 (SOS1)
05206 MicroRNAs in cancer
126023864 (SOS1)
05205 Proteoglycans in cancer
126023864 (SOS1)
05207 Chemical carcinogenesis - receptor activation
126023864 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
126023864 (SOS1)
05231 Choline metabolism in cancer
126023864 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
126023864 (SOS1)
05225 Hepatocellular carcinoma
126023864 (SOS1)
05226 Gastric cancer
126023864 (SOS1)
05214 Glioma
126023864 (SOS1)
05221 Acute myeloid leukemia
126023864 (SOS1)
05220 Chronic myeloid leukemia
126023864 (SOS1)
05211 Renal cell carcinoma
126023864 (SOS1)
05215 Prostate cancer
126023864 (SOS1)
05213 Endometrial cancer
126023864 (SOS1)
05224 Breast cancer
126023864 (SOS1)
05223 Non-small cell lung cancer
126023864 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
126023864 (SOS1)
05160 Hepatitis C
126023864 (SOS1)
05163 Human cytomegalovirus infection
126023864 (SOS1)
05165 Human papillomavirus infection
126023864 (SOS1)
09165 Substance dependence
05034 Alcoholism
126023864 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
126023864 (SOS1)
01522 Endocrine resistance
126023864 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
DUF6018
Takusan
Motif
Other DBs
NCBI-GeneID:
126023864
NCBI-ProteinID:
XP_049640200
LinkDB
All DBs
Position
12:complement(102024836..102132204)
Genome browser
AA seq
1330 aa
AA seq
DB search
MQAPPPPYEFFSDDNAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QTQPRSASDVEERVQKSFPHPIDKWAIADAQSAIDKRKRRNSLSLPVEKIHSLLIKEVLG
YKIDNQFSNYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQD
VEDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSA
NDVENIFSRIVDIHELSVKLLGLIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYA
RDILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQ
LEEKSEDEEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAI
RKMNEIQKNIDGWEGKDIGQCCNEFIMEGTLSRVGAKHERHIFLFDGLMICCKSNHGQPR
LPGASSAEYRLKEKFFMRKIQINDKDDTVEYKHAFEIILKDGNSVIFSAKSAEEKNNWMA
ALISLQYRSTLERMLDVTMLQEEKEEHLRLPSADVYRFAEPDSEENILFEDNVQLKAGIP
IIKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEAD
RIAIENGDQPLSAELKRFRKEYVQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIG
TVRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPPVEWHLSKPGQVENFDLLTL
HPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEIHSPNLLKMIRHTTNLTLWFEKCI
VETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKK
ILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFS
KRRKVAEITGEIQQYQNQPYCLRVESDMKRFFENLNPMGYSMEKEFTDYLFNKSLEIEPR
NFKPPPRFPKKYTYTLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPENDAEGTASA
PNSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDAVFIQVAQPHGPRSASVSSIS
FTRATEEGPVPPPVPPRRRPESAPGESSPSKILSKHADNPPAIPPRQPTSKAYSPRYSLS
ELPDSPSPPLVPPREPVRTPDVFSSSPLHLQPPPLGKKGDHGNAFFPNSPSPFTPLPPQT
PSPLGPRRQLPSPPAPQEADPPPTAGPPVPPRQSTSQLIPKLPPKTYKREHPHPPVHRDG
PPLLENAPSS
NT seq
3993 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgccgccgccgccctacgagttcttcagcgacgacaacgcgcccaagtggcgg
gggctgctggtgcccgcgctcaagaaggtccaggggcaagtccacccgaccctcgagtct
agtgacgatgctcttcagtatgtcgaggaactcatcttgcagctcctgaacatgctgtgt
cagacgcagccccggagcgcttctgacgtggaggaacgtgttcagaaaagtttccctcat
ccaattgataagtgggcaatagcagatgcccagtcagccatcgacaagaggaagcgaaga
aactctttgtctctcccagtagaaaaaattcattctttgttaataaaggaggtcctaggt
tataaaattgacaaccagttttctaattatatagtagcagtattagaatacatttctgca
gacattttaaagctggtggggaattatgtgcggaatatacggcattatgaaatcacaaag
caagatattaaagtggcaatgtgtgcagacaaggtgctgatggacatgtttcaccaagat
gtagaagatataaatatattatctttgactgatgaagagccttccacctcaggagagcag
acttactatgatctagtgaaagcattcatggcagaaattcgacagtatataagggaacta
aatttaatcataaaagtctttagagagccatttgtctccaactcaaagttgttttcagcc
aatgatgtagaaaacatcttcagtcgtatagtagatatacacgaactcagtgttaagttg
cttggcctcattgaagatactgtggagatgacagatgaagggagtccccacccattagtt
gggagctgcttcgaagacttggcagaggaactggcatttgatccttatgaatcatatgct
cgagatattttacgacccggtttccacgatcatttccttagccagttgtcgaagcctggg
gcagcactctatctgcagtcaataggtgaaggtttcaaagaagctgttcagtatgttctg
cccaggctccttctcgccccagtttatcactgtctacactactttgaacttttgaagcag
ctcgaagaaaaaagtgaggatgaggaagacaaggaatgcttgaaacaagcaataacagcg
ctgctgaatgttcagagcggaatggagaagatctgctccaaaagtcttgcaaaacgaaga
ctgagtgaatctgcatgtcggttttatagccagcaaatgaaggggaagcagcttgccatc
aggaagatgaacgagatccagaagaacatcgacggctgggagggcaaggacattgggcag
tgctgcaacgagttcatcatggaaggcaccctcagccgcgttggagccaagcacgagaga
cacatcttcctcttcgacggcctcatgatctgctgcaagtccaaccacgggcagcccagg
ctccccggagccagcagcgccgagtaccggctgaaggagaagtttttcatgaggaagatc
cagatcaacgacaaggacgacactgtggagtacaagcacgcctttgagatcatcctcaaa
gacgggaacagcgtgatcttctcggccaagtccgccgaggagaagaacaactggatggcg
gcgctgatctccctgcagtaccggagcacactggagcgcatgctggacgttaccatgctg
caggaggagaaggaggagcacctgaggctccccagtgccgacgtgtacagattcgcggag
ccggactcagaggagaacatcctctttgaggacaatgtgcagcttaaagctgggatcccc
atcatcaaggcagggactgtcatcaagctcattgagagactcacgtaccacatgtacgca
gatcccaattttgttcggacatttcttacaacatacagatcattttgtaaacctcaagaa
ctactgagtcttatcatagaaaggtttgagattcctgagccggagccaacagaagccgat
cgcatagcaatagaaaacggagaccagcccttgagtgcagagctgaagaggttccggaag
gagtacgtccagcccgtgcagctgcgagtcctgaacgtgtgtcggcactgggtggagcat
cacttctatgattttgagagagatgcagatcttttgcagcgaatggaagaatttatcgga
actgttcgaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaagg
aaaaaaattgcaagagacaatggaccaggtcataatattacctttcagagctcacctccc
cccgtggaatggcacctcagcaagcctgggcaagtcgagaactttgacctgctcacccta
cacccgatagaaatcgctcgtcagctcactctcctggagtcagacctctatcgagctgta
cagccatcagaattggttggaagtgtgtggaccaaagaagacaaagaaatccactctcct
aatcttctgaaaatgatccgccatacgaccaacctcacgctgtggtttgagaagtgcatt
gtcgaaacagaaaacttagaagaaagggtggcggtcgtgagcaggataatcgagattctg
caagtctttcaagagctgaacaacttcaatggggtgctggaggtcgtcagtgccatgaac
tcctcgcctgtttacagactagaccacacattcgagcaaataccaagtcgccaaaagaaa
attttagaagaagctcatgaattaagtgaagaccactataagaaatatttggcaaaactc
aggtctattaatccaccgtgtgtgcctttctttggaatttatctaactaatatcttgaaa
acagaagaaggcaaccctgaggtcctcaaaaggcatggaaaagagcttataaattttagc
aaaaggagaaaagtagcagaaataacaggagagatccaacagtaccaaaatcagccttac
tgtttacgagtagaatcagatatgaaaaggttctttgaaaacttgaatccaatgggatac
agcatggaaaaagaatttacagattatcttttcaacaagtccctagaaatagaaccacga
aactttaagcctcctccaagatttccaaaaaaatatacctataccctaaaatctcctggt
gttcgtccatcaaacccaagaccaggtaccatgagacaccccacacctctccagcaggag
cctcggaagatcagctacagccggatccctgagaatgatgctgagggcactgcatcagca
cccaactccccccgcaccccgctgaccccaccgccagcttcaggcgcttccagcaccact
gacgtctgcagcgtgtttgattccgaccactcaagcccctttcactcaagcagtgatgcc
gtctttatccaagtggctcagccccatggcccaaggtctgcgtcagtgtcatctatcagt
ttcaccagggccaccgaggaagggcctgtccccccgcctgttcctccgaggagacggcca
gagtcggcgccgggggaatcgtcgccatctaagatcctgtccaagcacgcagacaaccct
ccggccatccctccacggcagcccacgtccaaagcctactccccgcggtactccctgtcc
gagctcccggacagccccagcccgcccctcgtgcccccacgggagcccgtgcggaccccc
gatgtcttctccagctcgcccctacacctccagccgcccccgctgggcaagaagggcgac
cacggcaacgccttcttccccaacagcccgtccccgttcaccccgctgcccccccagacg
ccctctcctctcggcccccggagacagctgccctcgcccccggcgcctcaggaagccgac
ccaccccccacggccgggcctcccgtgccgccgcgccagagcacttcgcagctcattccc
aaactccctccgaagacctacaagcgagagcacccacacccgccggtgcaccgggacggg
ccgccgctgctggagaacgcgccttcctcctga
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