Suncus etruscus (white-toothed pygmy shrew): 126029612
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Entry
126029612 CDS
T09902
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr00310
Lysine degradation
setr01100
Metabolic pathways
setr05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
126029612 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
126029612 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
setr03036
]
126029612 (DOT1L)
Enzymes [BR:
setr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
126029612 (DOT1L)
Chromosome and associated proteins [BR:
setr03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
126029612 (DOT1L)
HMT complexes
Dot1-containing complex
126029612 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
126029612
NCBI-ProteinID:
XP_049643867
LinkDB
All DBs
Position
15:83726646..83759255
Genome browser
AA seq
1517 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPLKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCR
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRESKSSTSTPTKAP
ESKAAAANNNPNANAAAAAPVDAPLDSGAEEEKAGATTVKKPSPSKARKKKLNKKGRKMA
GRKRGRPKKLSAAHPERKPRKGQTPLELLHSQTAPDAAGASPSPQDAYKSPHSPFYQLPP
SVQRQPPDQLLLAPTPPALQKLLESFKVQYLQFLAYTKTPQYKANLQQLLDQEKEKNARL
LGAAQQLLGHCQAQKDEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNRQLREQTEQL
EKDTRTLRGQSLQLLKARCEELKLDWATLSLEKLLKEKQALRSQISEKQRRCLELQISIV
ELEKSQRRQELLQLKSCGPPDEGLGPQPSRLPPELDASKFSLAPFSGLSPELSLNGHAAG
YELCGALSRPPSKQNTPQYLASPLDQEVVPCTPNHGGRPRLDKLAGLSLPDYTRLSPAKL
VLRRHLSQEPTTGAKASGELHPRAEHTKENGSPSLVNGIKLSPQDPWPTSPGALPTAGEK
SSEKGLKERGSSSSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRVEKRSTPSPVP
QAREATMLDKVGTSTYGASSKGLVPVPTGFYAGSVAISGALTGSPASLAPGTEPPTFDES
SSSGSLFGTMGSRSSTPQHPPLLAQSRGAGSGSPAHQLCASPRLNGAPQGPLLDPSKGEL
PAEASSSDPESDTKRRIVFTLSGSTKQSPSHKHSTLSTGTSSHGPDSRKRGRRKRAAATG
TPSLSSGVSPKRRALPAVAGLFTPSSGSPLNLNSMVSNINQPLEITAISSPESSLKSSPV
PYQDDQPPVLKKEKPLGPSNGAQYSPLTSDEEPGSEDEPASARIERKIATISLESKSPPK
ALENGGSVPGRKVPLVGEPVNSSKWKATFSPISDLGLPKAADSPLQAGAALAQGSLFAFR
PTLDEVTADPKLAAHGRKGFAGPLAAGGLSPNSNSPSSFAFSDLSLHSFNDGAGLALKGS
EAAGLSFPGPRAKEGAAEPGPFQNKRQLDGLGGSKGEAGKGKEAAEPGLPPSGAPDKSSL
MHGAKAGRGRDREADFKGGPNLFISAAAVPPGGLLSGQGLSTATSSSAGSAAASAQTHRP
FLGTFAPAPQFSLGPMSLQANLGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFS
GVAGGAVGGRKGSVSSA
NT seq
4554 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgccagtgggagccgagcccgccgtctac
ccgtggccgctgcccgtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaagaaatccctgatctcaagctcgccatggagaattacgtttta
attgactacgatactaaaagctttgaaagcatgcagcggctctgtgacaagtacaaccga
gccattgacagcatccatcagctgtggaagggcaccacgcagcccctgaagctcaacacg
cggccatccacggggctgctccggcacatcctgcagcaggtctacaaccactcggtcacg
gaccccgagaaactcaacaactacgagcccttctcccctgaggtgtatggtgagacctct
ttcgatctggtggcgcagatgattgatgagatcaagatgaccgaggatgacctcttcgtg
gatctgggcagcggtgtgggccaggtggtgctgcaggtcgcggcagccaccaactgccgg
catcactacggcgtggagaaagccgacatcccggccaagtacgcggagaccatggaccga
gagttccggaagtggatgaaatggtacgggaaaaagcatgcagagtacacactggaaaga
ggcgacttcctctcagaagagtggagggaacgtatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaagagcgctttgcaaacatg
aaggaaggtggcagaattgtgtcctcaaagccttttgcccccttaaacttcagaatcaac
agcagaaacttgagcgacattggcaccatcatgcgcgtggtggagctgtccccactgaag
ggctccgtgtcgtggacagggaagccagtctcttactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatcccaaactcagggaggagcaggaggct
gcgcggcggcgacagcagcgggagagcaagagcagcacgtccacccccaccaaggcgccc
gagagcaaggccgccgccgccaacaacaaccctaacgccaacgccgcagccgcagccccc
gtggacgcgcccctggactctggtgctgaggaagagaaagccggggcgaccaccgtcaaa
aagccatctccctccaaagcccgcaagaagaagctgaacaagaaggggcgcaagatggca
ggccggaagcggggccgccccaagaagctgagcgccgcacaccccgagcgcaagccccgc
aaaggccagacgccactggagctgctgcactcgcagacggcgccggacgccgctggcgcc
tcgccctcaccccaggatgcctacaagtcacctcacagccccttttaccagctacctccc
agcgtgcagcgccaaccccccgaccagctgttgctggcccccaccccgcctgcactgcag
aagctgcttgagtccttcaaggttcagtatctgcagttcctggcatacaccaagaccccg
cagtataaagccaacctgcagcagctgctggaccaggagaaggagaagaatgctcggctc
ctgggtgccgcacagcagctgctcggccactgccaggcccagaaagatgagattcggcgg
ctgtttcagcagaagctggacgagctgggtgtgaaagcgctgacctataacgacctgatc
caagcccagaaagagatctcagcgcacaaccggcagctgcgggagcaaactgagcagctg
gagaaggacacgcggacactgcggggccagagcctgcagctgctcaaggctcgatgcgag
gagctgaaactggactgggccacactgtcactggagaagctgctaaaggagaagcaggcg
ctgaggagccagatctctgagaagcagaggcgctgcctagagctacagatcagcatcgtg
gagctggagaagagccagcgacgccaggagctcctacagctcaagtcgtgtgggcccccc
gatgagggcctggggccgcagcccagccggctgccccctgagttggatgcctccaaattc
tccctggctcccttcagcggcctgagccctgagctctccctcaatggtcatgcagctggc
tacgagttgtgtggggcgctcagccggcccccatccaagcagaacacccctcagtacctg
gcatcgcccctggatcaggaggtggtgccctgcacccccaatcatggcggccgtccacgc
cttgacaagctggcaggcctgtccctgcctgactacacccgcctctcaccagctaagctg
gttctgcggcgacacttgagccaggagcccaccactggtgcaaaggcctcgggtgagctg
caccctcgggccgagcataccaaggagaatggtagtcccagcctggtcaatggcattaag
ctgagcccccaggatccatggcccacatccccaggggccctgcccacagctggggagaag
agcagtgagaagggtctgaaggagcgtggctccagcagcagcggtgaggccatcaccagc
ctgcccgtcagcatcccgctcagcacggtgcagcccagcaagttgcccgtcagcatcccc
ctagccagtgtggtgctgcccagccgtgtcgagaagagaagcactcccagccctgtgccc
caggcccgagaggctaccatgctggacaaagtgggcaccagcacctatggagcaagcagc
aaaggcctggtaccggtgcccacaggtttctacgcaggttcagtagccatcagtggagcc
ctcacaggcagcccagcctccctggcacctggaactgagccccccacctttgatgagtct
tctagctccgggagcctctttggcaccatgggatcccgcagctccaccccgcaacatccc
ccactgctggcacagtcccggggtgcaggctccggctccccagcccaccagctctgtgcc
agccctcggctcaacggggctccccagggcccacttcttgaccccagcaagggggagctg
ccagcggaggccagcagttcggaccccgagagtgacaccaaaaggcggattgtgttcacc
ctgtcaggcagcaccaagcagtctccctctcacaaacacagcaccctgtccacgggcacc
tcaagccatggccccgacagtcgcaagcgtggtcgcaggaagcgggcagcagcaacaggg
acccccagcctaagctcgggggtgtcccctaagcgccgggccttgccagctgtggctggc
ctcttcacaccatcatcgggttccccgctgaacctcaactccatggtcagcaacatcaac
cagcccctggagatcaccgccatctcgtcccctgagagctcactcaagagctcccccgta
ccctaccaggatgaccagccccctgtgctcaagaaggagaagccactgggcccaagtaat
ggtgcccagtactcaccactcacctcggacgaggagccaggctctgaggatgagccagcc
agtgccagaatcgagcggaaaattgctaccatctccttagaaagcaagtctcctccgaaa
gctctggaaaatgggggcagcgtgcctgggaggaaagtgccgctggtgggcgagccagtg
aacagcagcaagtggaaggccaccttctcccccatctcggacctcggcctgcccaaggca
gccgacagccccctgcaggcgggcgcagcactggcccagggctccctgtttgccttccgc
cccaccctggatgaagtgacagctgaccccaagctggctgcgcatgggcgcaaaggcttc
gcgggccctctggcagcaggggggctcagccccaacagcaactcccccagtagcttcgcc
ttttccgacctcagtttacacagcttcaatgacggtgctgggctggccctcaagggttcc
gaggcggctggcttgagttttcccggcccccgggccaaggagggtgctgctgagccaggc
cccttccagaacaagaggcagctggatggactggggggctccaagggcgaggctggcaaa
ggcaaggaggctgcagagccgggcttgccccccagtggggctcctgacaagtcctcgctg
atgcatggggccaaagctggtcgaggtcgagaccgagaggctgacttcaagggcggaccc
aaccttttcatctcggcagccgctgtgccccccgggggccttctcagcggccagggcctc
agcactgcgacttcgtcctctgccggcagcgcggccgcctctgcgcagacgcaccggccc
ttcctgggcacctttgcgccagccccccagttctccctgggccccatgtcccttcaggcc
aacctgggctcatccgtgctccagtccctgttcagctcggtgcccgccgccgcgggcctg
gtgcatgtctcgtccgccgccaccagactgaccaactcgcacgccatgggcagcttctcc
ggggtggccggcggggccgtcggaggtaggaaggggagcgtgtcttccgcctga
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integrated database retrieval system
