Suncus etruscus (white-toothed pygmy shrew): 126030288
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Entry
126030288 CDS
T09902
Symbol
KEAP1
Name
(RefSeq) kelch-like ECH-associated protein 1
KO
K10456
kelch-like protein 19
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr04120
Ubiquitin mediated proteolysis
setr05012
Parkinson disease
setr05200
Pathways in cancer
setr05208
Chemical carcinogenesis - reactive oxygen species
setr05225
Hepatocellular carcinoma
setr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
126030288 (KEAP1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
126030288 (KEAP1)
05208 Chemical carcinogenesis - reactive oxygen species
126030288 (KEAP1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
126030288 (KEAP1)
09164 Neurodegenerative disease
05012 Parkinson disease
126030288 (KEAP1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
126030288 (KEAP1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
setr04121
]
126030288 (KEAP1)
Ubiquitin system [BR:
setr04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
Cul3 complex
Adoptor and target recognizing subunit (BTB)
126030288 (KEAP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Kelch_1
Kelch_6
BACK
Kelch_2
Kelch_3
Kelch_KLHDC2_KLHL20_DRC7
BTB
Kelch_4
Beta-prop_ATRN-LZTR1
BTB_KLHL33
NANM
Motif
Other DBs
NCBI-GeneID:
126030288
NCBI-ProteinID:
XP_049644424
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Position
15:complement(90007265..90024419)
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AA seq
627 aa
AA seq
DB search
MQSKARPSGAGARTRFLPLPPTQTQGHQGPGDAGMFASTECKAEVTPSPHGHRTFSYTLE
DHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLASSSPVFKAMFTNGLRE
QGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQ
QLDPSNAIGIANFAEQIGCAELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDL
NVRCESEVFHACIDWVKYDCEQRRFYVQALLRAVRCHALTPHFLQLQLQKCEILQSDARC
KDYLVQIFQELTLHKPTQVMPCRAPKVGRLIYTAGGYFQQSLSYLEAYNPSDGQWLRLAD
LQVPRSGLAGCVVGGLLYAVGGRNNNPDGNMDSNALDCYNPMTNQWSPCAPMSVPRNRIG
VGVIDGHIYAVGGSHGCVHHNSVERYEPEHDKWYLVAPMLTRRIGVGVGVLNRLLYAIGG
FDGTNRLNSAECYYPERNEWRMITPMNSIRSGAGVCVLHNCIYAAGGYDGQYQLNSVERY
DVETETWTFVAPMRHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDMDTWTEVTRM
TSGRSGVGAAVTMEPCRKQIDQQSCTC
NT seq
1884 nt
NT seq
+upstream
nt +downstream
nt
atgcagtccaaagccaggcctagcggggctggggcccgcacgcgattcctgccgctgcca
ccgacacagacgcagggccaccaggggcctggggacgcggggatgttcgcctccaccgag
tgcaaagccgaggtgacgccgtcaccccacggccaccgcacgttcagctacaccctggaa
gatcacaccaaacaggccttcggcatcatgaacgagctgcgactcagccagcaactgtgc
gacgtgaccttgcaggtgaagtaccaggacgcaccggccgcccagttcatggcgcataag
gtggtgctggcctcgtccagccccgtcttcaaggccatgttcaccaacgggctccgcgag
cagggcatggaggtggtgtccatcgagggcatccaccccaaggtcatggagcggctcatc
gaattcgcctacacggcgtccatctccatgggcgagaagtgtgtcctgcatgtcatgaac
ggggcggtcatgtaccagatcgacagcgtcgtgcgcgcctgcagcgactttctagtgcag
cagctggaccccagcaacgccattggcattgccaacttcgccgaacagattggctgtgct
gagctgcaccagcgtgcccgcgagtacatctacatgcactttggggaggtggccaagcag
gaggagttcttcaacctgtcgcactgccagctggtgacgctcatcagccgcgacgacctg
aacgtgcgctgcgagtcggaggtgttccacgcgtgcatcgactgggtcaagtacgactgc
gagcagcggcgcttctacgtgcaggccctgctgcgggccgtgcgctgccacgcgctcacg
ccgcacttcctgcagctgcagctgcagaagtgcgagatcctgcagtcggacgcgcgctgc
aaggactacctggtgcagatcttccaggagctgacgctgcacaagcccacgcaggtcatg
ccctgccgcgcccccaaggtgggccgcctcatctacacggccggcggctacttccagcag
tcgctcagctacctggaggcctacaaccccagcgacggccagtggctgcgcctggccgac
ctgcaggtgccccgcagcggcctggcgggctgcgtggtcggggggctgctctacgccgtg
gggggccgcaacaacaaccccgacggcaacatggactccaacgcgctcgactgctacaac
cccatgaccaaccagtggtcgccctgcgcccccatgagcgtcccccgcaaccgcatcggc
gtgggggtcatcgacggccacatctacgccgtggggggctcccacggctgcgtccatcac
aacagtgtggagaggtacgagccggagcacgacaagtggtacctggtggcgccgatgctg
acgcggaggatcggcgtgggcgtgggcgtgctgaaccggctgctctacgccatcgggggc
ttcgacggcaccaaccgcctcaactcggccgagtgttactacccggagcgcaacgagtgg
cgcatgatcacgcccatgaacagcatccggagtggggcaggggtctgcgtcctgcacaac
tgcatttacgccgcggggggctacgacggccagtaccagctcaacagcgtggagcgctac
gacgtggagacggagacgtggaccttcgtggcccccatgaggcaccggcgcagcgccttg
gggatcaccgtgcaccagggccggatctacgtcctgggaggctacgacggtcacacgttc
ctggacagcgtggagtgctacgaccctgacatggacacatggaccgaggtgacacgcatg
acttcaggccgcagtggggtgggtgccgcggtcaccatggagccttgtcgaaagcagatc
gaccagcagagctgcacctgctga
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