KEGG   Suncus etruscus (white-toothed pygmy shrew): 126030732
Entry
126030732         CDS       T09902                                 
Symbol
NOS2
Name
(RefSeq) nitric oxide synthase, inducible
  KO
K13241  nitric-oxide synthase, inducible [EC:1.14.13.39]
Organism
setr  Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr00220  Arginine biosynthesis
setr00330  Arginine and proline metabolism
setr01100  Metabolic pathways
setr04020  Calcium signaling pathway
setr04066  HIF-1 signaling pathway
setr04146  Peroxisome
setr04371  Apelin signaling pathway
setr04926  Relaxin signaling pathway
setr05010  Alzheimer disease
setr05014  Amyotrophic lateral sclerosis
setr05022  Pathways of neurodegeneration - multiple diseases
setr05133  Pertussis
setr05140  Leishmaniasis
setr05142  Chagas disease
setr05145  Toxoplasmosis
setr05146  Amoebiasis
setr05152  Tuberculosis
setr05200  Pathways in cancer
setr05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:setr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    126030732 (NOS2)
   00330 Arginine and proline metabolism
    126030732 (NOS2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    126030732 (NOS2)
   04066 HIF-1 signaling pathway
    126030732 (NOS2)
   04020 Calcium signaling pathway
    126030732 (NOS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    126030732 (NOS2)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    126030732 (NOS2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    126030732 (NOS2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    126030732 (NOS2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    126030732 (NOS2)
   05152 Tuberculosis
    126030732 (NOS2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    126030732 (NOS2)
   05145 Toxoplasmosis
    126030732 (NOS2)
   05140 Leishmaniasis
    126030732 (NOS2)
   05142 Chagas disease
    126030732 (NOS2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    126030732 (NOS2)
   05014 Amyotrophic lateral sclerosis
    126030732 (NOS2)
   05022 Pathways of neurodegeneration - multiple diseases
    126030732 (NOS2)
Enzymes [BR:setr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     126030732 (NOS2)
SSDB
Motif
Pfam: NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Dgt5 NAD_binding_6
Other DBs
NCBI-GeneID: 126030732
NCBI-ProteinID: XP_049644964
LinkDB
Position
1:complement(164720937..164759431)
AA seq 1269 aa
MREGLGSACEAARPRLCRLFRRILRSKPACGPHGASIFQECELDFVKSNFNPATQDDPKG
QNSLSHKLRNESPQSHKNTERKSPEPPVKTDVTQVTCPRYMKIKNWGSGTSFQDTLHHKA
KKDLACKSKSCHGAIMNPKSLIIGPKDKPTSPDELLPQAVDFINQYYDSFKEAKIEAYLA
RVEAVTKEIEITGTYQLTGDELIYATKQAWRNAPRCIGRIQWSNLQVFDARSCTTAQEMF
EHICRHIRYATNNGNIRSAITVFPQRSDGKHDFRVWNSQLIRYAGYQMPDGTIRGDPACV
EFTQLCIDLGWKPKYGRFDVVPLVLQADGRDPELFEIPPDLVLEVPMEHPKYEWFQELGL
KWYTLPAVANMLLEAGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETH
KLASLWKDRAVIEVNIAVLHSFQKQNVTIMDHHSASESFMKYMQSEYRARGGCPADWIWL
VPPISGSITPVFHQEMISYVLSPFYYYQVEAWKTHVWTDGKRRPRRNEIHFRVLVKAVLF
SSVLMHKTMAFRVRATILFATETGRSEMLARDLGDLFSCAFNPKVLCMDEYQIDSLEEEQ
LLLVVTSTFGNGDSPSNGQKLKKSLFMLKKLTNKFRYAVFGLGSSMYPQFCAFAQDIDQK
LSLLGASQLTPTGEGDELSGQEEAFRGWAVQTFKAACESFDVRGKNHIEIPKRYSSNVKW
EPQHYRLVQDSQPWDLSKALSSMHAKNVITVNLKSLQPLQGPKSSRSVLLVELSCKNCPS
LSYLPGDHLGVYAGNQPALVQGILERLADGSVPHQPVSLETLDESGSYWVKDRRLPPCSL
SQALTYFLDITTPPSQLLLRKLVLLATDEDEKRRLEELSQPSEYNKWKFTHSPTFLEVLE
EFPSLRVPASFLLSQLPLLKARYYSISSSAARSPSELHLTVAVLTYRTRGGQGPLHHGVC
STWLSTLKPGDPVPCFLRSANNFQLPQDPSQPCILVGPGTGIAPFRSFWQQRLYEAEHKG
LQGGRLTLVFGCRHPEEDHLYREEMLEMVQKGVLHEVHTAYSRLPGQPKVYVQDILRERL
EGEVLRVLLEERGHIYICGGVCMAHDVAHTLRQLVAAALSLSEEQVEDYFFQLKSQERYH
EDIFGAVFPHKARKDEALELPDNPEALVPFTKKCEVETAGMEATVDFLPSLSHYQVGGSH
PHTAGSLPGPNPHINNFPTNIPDPLPIPTFSWMLPQSSASLEARTKLGPSDCPDPSLPSS
LHPSIWQLL
NT seq 3810 nt   +upstreamnt  +downstreamnt
atgcgcgaggggctgggcagcgcctgtgaggccgcccggccccggctgtgccgactcttc
cgcaggatcctccggtccaagcccgcctgcggcccccacggagccagcattttccaggag
tgtgagctggacttcgttaagtccaacttcaatccggcgacacaggatgatccaaaaggc
caaaacagcctcagccacaagctccggaatgagtccccccaatctcacaaaaacacggaa
aggaaatctccagaacccccagttaagacagatgtgacccaagtgacctgcccacggtac
atgaagatcaaaaactggggcagtgggaccagtttccaagacacacttcaccacaaagct
aaaaaggatcttgcttgcaagtccaagtcttgccatggggccatcatgaacccaaaaagt
ttgatcattggacccaaggacaagcctacctccccagatgagcttctacctcaagcagtt
gactttatcaaccaatattatgactctttcaaagaggcaaaaatagaggcatatctggcc
cgagtggaagcggtaacaaaggagatagaaataacaggaacctaccagctgacaggggat
gagctcatctacgccaccaagcaggcctggcgcaacgccccccgctgcattgggaggatc
cagtggtcaaaccttcaggtcttcgatgcccggagctgtaccactgcccaggaaatgttc
gagcacatctgcagacacatccgttatgccaccaacaatgggaacatcaggtcggccatc
actgtgttcccccagcggagtgatgggaagcatgacttccgagtgtggaactcgcagctc
atccgctatgcaggctaccagatgcccgatggcacgatccgcggggacccggcctgcgtg
gagttcacccagctgtgcatcgacctgggctggaagcctaagtatggacgctttgatgtg
gtgccactggtcctgcaagccgatggccgcgacccagaactctttgaaattcctcctgac
ctggtgcttgaggtgcctatggagcatccaaagtacgagtggttccaggagctggggctg
aagtggtacactctgcctgcagtggccaatatgctgctggaagcaggtggccttgagttc
ccggggtgtcccttcaatggctggtacatgggcacagagattggggtccgggacttctgt
gacgtccagcgctacaatatcctggaggaagtgggccgaaggatgggcctggagacacac
aagctggcctccctctggaaagaccgagctgttattgaagtcaacatcgccgtgcttcat
agtttccagaagcaaaatgtcaccatcatggaccaccactcagcctctgaatctttcatg
aaatacatgcagagcgagtaccgggcccgtgggggttgcccagctgattggatttggctg
gtccccccaatatctgggagcatcacccctgtgttccaccaggagatgataagctacgtc
ttgtcccctttctactactatcaggtggaagcctggaaaactcacgtctggacagatggg
aagcggagacctcgcagaaatgagattcacttcagagtcttggttaaggccgtacttttt
tcctctgtcctgatgcacaagaccatggcattccgagtcagagctacgatcctctttgca
acagagacagggcgatcggaaatgctggcccgggacctaggggacctgttcagctgtgcc
ttcaaccccaaggttctctgcatggacgaataccaaattgacagcctggaggaggagcag
ctgttactggtggtgaccagcacattcgggaatggagattcccccagcaatggtcagaaa
ttgaagaaatccctctttatgttgaaaaagctcaccaacaagttcaggtatgccgtgttt
ggcctcggctccagcatgtaccctcagttctgcgcctttgctcaagacattgaccagaag
ctgtctctcctgggggcatctcagctcaccccgacaggggaaggggatgaactcagtgga
caagaggaggcatttcgtggctgggctgtgcaaaccttcaaggcagcctgtgagagtttt
gatgtccgaggcaagaaccacattgagatccccaaacgctacagctccaacgtgaagtgg
gagccacagcactacaggctagtgcaggactcacagccttgggacctcagtaaagccctc
agcagtatgcacgccaagaatgtgatcactgtgaatctcaaatcgctgcagcctctccag
ggcccaaaatccagccgctctgtcctcctggtagaactttcctgcaaaaactgtcccagc
ctgagctacctgcctggagaccacctcggggtttatgcaggcaaccagccagcactggtc
cagggcatcttggaaagattggcagatggctctgtaccccaccaacccgtgagcttggag
accctcgacgagagtggaagctactgggtgaaggacagacggctgcccccctgctccctc
agccaggccctcacctacttcctggacattaccacaccccccagccagctattgctccgg
aaactagtgctgcttgccacagacgaggatgagaagcgaagactagaggagctgagccag
ccctcggagtacaacaaatggaagttcacccacagtcccaccttcttggaggtgctggag
gaattcccgtcgctgcgggtgccggctagcttcctgctctcgcagctccccctactgaaa
gcccgctactattccatcagctcctctgcggcccgctctccctccgagctccacctcacc
gtggcggtgctcacctatcgcacccgaggtggccagggtcccctgcaccatggcgtctgc
agcacgtggctcagcaccctgaagcctggagaccctgtaccctgctttttgcgaagtgcc
aacaacttccagctgcctcaggacccttcccaaccttgcatccttgtcggccccggcacg
ggcattgccccctttcgcagtttctggcagcagcgtctctatgaagctgaacacaaaggg
ctacagggcggccgtctgaccttggtatttgggtgtcgtcacccagaggaggatcacctc
tatcgggaagagatgctagagatggtccagaagggggtactgcatgaagtgcacacagcc
tattctcgtctgcctggccagcccaaggtctatgtacaggacatcctgcgagagcggctg
gaaggcgaggtgcttcgtgtgttacttgaggagcgaggtcacatctacatctgtgggggc
gtgtgcatggcccatgatgtggcccacaccctgaggcagctggtggctgctgcattgagc
ctgagcgaggagcaggtggaggattatttcttccagcttaagagccaggaacgctaccat
gaggatatcttcggtgctgtgtttccccacaaggcaaggaaggatgaggccttggagctg
cccgataatcctgaagctctggtccctttcacaaagaagtgtgaagtcgaaactgcaggc
atggaagcgactgttgatttcctgccatcactgtcccattaccaggtagggggcagccac
ccccacactgcagggtccctgcccgggccgaacccacacatcaacaactttcccaccaac
atcccagaccccctccccatccccaccttctcctggatgctgcctcagtcatcagcctct
ttagaagcaaggactaaacttgggccttcggactgcccagacccctccctcccatcctca
ttgcaccccagtatttggcaactgctgtag

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