KEGG Orthology (KO) [BR:setr00001]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
126031380 (EGLN1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
126031380 (EGLN1)
09162 Cancer: specific types
05211 Renal cell carcinoma
126031380 (EGLN1)
Enzymes [BR:setr01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
1.14.11.29 hypoxia-inducible factor-proline dioxygenase
126031380 (EGLN1)
422 aa
MANDSGGPGGPSASERDRQYCELCGKMENLLRCSRCRSSFYCSKEHQRQDWKKHKLVCQS
SEGPPPPPPTPPGPAPARPSGGALRAPREAKKGPRRRDGAAEPPAEGDATQASKAKAKPS
AEAEPRKAPSGPGFAALETEGKEEPLGRASPYREKANLYPPSNAPGEGLSHGGGPRPNGQ
TKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGMQIGDEVRALHDTGRFTDGQLVSQK
RDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGNYKINGRTKAMVACYP
GNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGVLRIFPEGKAQFADIEPKFDRLL
FFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDSVSKD
IL
