Saxibacter everestensis: LWF01_05945
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Entry
LWF01_05945 CDS
T10942
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sevr Saxibacter everestensis
Pathway
sevr00300
Lysine biosynthesis
sevr00550
Peptidoglycan biosynthesis
sevr01100
Metabolic pathways
sevr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sevr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LWF01_05945 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LWF01_05945 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LWF01_05945 (murF)
Enzymes [BR:
sevr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LWF01_05945 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF5046
Motif
Other DBs
NCBI-ProteinID:
WGW13308
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Position
1230699..1232201
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AA seq
500 aa
AA seq
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MKEFSYKQIAAAVGGEIVGADPELRTAGPVVTDSRDVSPGAVYVARRGESLDGLDFAASA
VQEGAALVIGEEVVHVDGVPLPSIVVEDATVALGLLAHANVTALRAKAPTGSDAGQPAGA
AAVDHGGLKVVAITGSAGKTTTKDLLADFLVSLGQTVWPPNSFNNEVGVPLTALRADEDT
RFLVLEMGAREPGNLSYLTSLVRPDIAVELNVGSAHSGIFGSVEATAKAKAELVQSLDSD
GIAVLNLDDDRVANMASKVADGVGIVWFSLSGRQHSTQPTVWAEDVTSDATGRTSFLLCL
PDGQTAQIQLALLGEHHVANALAAAAAAWRMGVSLTTISTVLATSGAASRWRMELVDSPS
GVTVLNDAYNANPDSMRSALKTLATMGRGDAQNPPRRTWAVLGEMLELGESSVEEHDSIG
RLVVRLNISRLLAVGEGARPIYQAANLEGSWGEEAAWVPDVAAARAFLNESLSPGDLVLF
KSSRDAGLRYLGDDVAGVTQ
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atgaaggaattttcttataagcagatagccgccgcagtcggcggcgaaatcgtaggcgcc
gatcccgagctacgcacggcgggcccggtcgtcaccgactctcgcgatgtcagccctggc
gcggtgtacgttgcccgcaggggcgaatcgctcgatgggctggattttgcagcctccgcg
gtccaggaaggagccgcgctcgtcatcggcgaggaagtggtccacgtcgacggcgtgccg
ttgccgtcgatcgtggttgaagacgcgacggttgcgctggggctgcttgcccacgccaac
gtcaccgcgcttcgtgccaaggcaccaaccgggtcggacgcagggcagcctgccggcgcg
gcagcagtggaccacggaggactcaaggtggtcgccatcaccggttcggccggtaagacg
acgaccaaggatctgctcgcggatttcctggtgtcgctgggacagactgtctggccaccc
aattctttcaacaacgaggtaggggtcccgctcaccgcattgcgggcggacgaggacact
cggttcctggtgctcgaaatgggcgcccgcgagcccggaaacctgagctacctgaccagc
ttggtccggccggacattgcggtggagctcaatgtgggctcggcgcacagcggcatcttc
ggcagcgttgaggcaaccgccaaagccaaagccgagcttgtccagtcactggacagcgac
ggaatagcggtgctgaaccttgacgacgaccgggtggccaacatggcctcgaaggttgct
gacggggtaggaatcgtctggttctcgctcagtggccgtcagcattccacccagccgacc
gtctgggccgaagatgtgacgagtgacgccaccggacggacatcgttcctgctgtgcctt
cccgatggacagacggctcagatccagcttgccctgctcggcgagcatcacgtggccaat
gcgcttgctgccgccgccgccgcgtggcggatgggtgtctcgctgacaacgatcagcact
gtgctggcaacgtccggcgcggcaagccgctggcggatggaactcgtcgactcaccgtcg
ggcgtcaccgtgctcaacgacgcctacaacgccaacccggattcgatgcggtcagctttg
aagacgctggcaaccatgggccgcggcgacgcgcagaacccgccgcggcgaacctgggcg
gtgctcggtgagatgctcgaactgggcgaatcctcggtcgaggagcacgattcgatcggg
cgcctggtcgtccggctcaatatctcccgcctgctggcggtaggcgaaggagcgcggccg
atctaccaggcggcgaatctcgagggttcgtggggcgaggaagctgcctgggtgccggat
gtcgccgctgcccgcgcctttctcaacgagtcactgagccccggcgaccttgtgctgttc
aagtcttcgcgggatgccggcctgcgctacctcggtgacgatgtcgcgggagtcacccag
tga
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