Salmonella enterica subsp. enterica serovar Schwarzengrund: SeSA_A0129
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Entry
SeSA_A0129 CDS
T00743
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
sew
Salmonella enterica subsp. enterica serovar Schwarzengrund
Pathway
sew00290
Valine, leucine and isoleucine biosynthesis
sew00620
Pyruvate metabolism
sew01100
Metabolic pathways
sew01110
Biosynthesis of secondary metabolites
sew01210
2-Oxocarboxylic acid metabolism
sew01230
Biosynthesis of amino acids
Module
sew_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sew00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SeSA_A0129 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SeSA_A0129 (leuA)
Enzymes [BR:
sew01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SeSA_A0129 (leuA)
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Gene cluster
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
ACF91724
UniProt:
B4TWW1
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Position
complement(132059..133630)
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIE
RAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKA
EAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattatttttgatacgaccttacgcgacggcgaacaagcgttacag
gccagcctgagcgcgaaagagaagctgcagattgccctggcccttgagcgcatgggggtt
gatgtcatggaagtaggcttcccggtctcttctccgggtgattttgaatctgtccaaacc
atcgcccgcaccatcaaaaacagccgcgtttgcgccctggcgcgttgtgtagaaaaagac
atcgacgtcgcggcacaggcgctgaaggtcgccgacgcgtttcgtattcatacttttatc
gccacctcgccaatgcacatcgccaccaagctgcgcagcacgctggatgaggtcatcgaa
cgcgcggtatacatggttaagcgggcgcgtaattacactgatgacgtggagttctcctgc
gaagatgctggccggacgcctgttgacgatctggcgcgcgtggtggaagccgctataaac
gccggcgcgagaaccattaatattcccgataccgtgggctataccatgccgtttgagttc
gcgggaatcatttccggcctgtatgaacgtgtccccaatattgacaaagctatcatctcc
gttcatacccacgacgatttagggatagcagtaggcaactcgctggcggcagtacatgcg
ggcgcgcgtcaggttgaaggcgcgatgaacggtatcggagaacgtgccggtaactgcgcg
ctggaagaagtaatcatggcgattaaagtgcgcaaagacatcatgaacgtacacaccaat
atcaatcaccacgaaatctggcgcaccagccagaccgtcagccagatctgtaacatgccg
atcccggccaacaaagcaattgtcggcagcggcgctttcgcccactcttccggcatccac
caggatggcgtcctcaagaaccgcgaaaactatgaaatcatgacgcctgagtccatcggt
ctgaaccagatacagctgaacctgacctcccgctctggccgtgccgccgtgaaacatcgc
atggaagagatgggttacaaagacacagactacaacatggaccacctgtacgacgcgttc
ctgaagctggcagacaaaaaaggccaggtgttcgactatgacctggaagcgctggcgttt
attaataaacagcaagaagaaccagagcatttccgtctggattacttcagcgtgcagtcc
ggctccagcgatatcgccactgcttccgtgaagctggcctgtggtgaagagatcaaggcc
gaggcggcgaacggcaacggcccggtcgacgccatctatcaggcgattaaccgtatcact
ggctacgacgttgagttggttaaatacgacctgaacgccaaaggccagggcaaagacgcg
ctgggtcaggtcgatatcgtcgtgaaccatcatggtcgccgcttccacggcgtcgggctg
gcgacggatatcgtcgaatcctccgccaaagcgatggtgcacgtactgaacaatatctgg
cgcgcagccgaagttgaaaaagaattgcaacgcaaagctcaaaataaagagaacaacaag
gaaaccgtgtaa
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